Development Level

Tbio 22 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased circulating creatine... 1 | 4
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 22 | 8,520
osteosarcoma 20 | 7,950
Carcinoma 19 | 11,493
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 13 | 5,792
medulloblastoma, large-cell 13 | 6,241
ependymoma 12 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
group 3 medulloblastoma 11 | 4,104
primitive neuroectodermal tumor 11 | 3,035
Breast cancer 10 | 3,578
pancreatic cancer 10 | 2,398
psoriasis 10 | 6,694
spina bifida 10 | 1,074
Cancer 9 | 2,499
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
subependymal giant cell astrocytoma 9 | 2,287
Astrocytoma, Pilocytic 8 | 3,081
breast carcinoma 8 | 1,638
lung cancer 8 | 4,740
adult high grade glioma 7 | 3,801
interstitial cystitis 7 | 2,312
juvenile dermatomyositis 7 | 1,187
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Pick disease 6 | 1,894
astrocytoma 6 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
Kidney cancer 5 | 2,613
gastric carcinoma 5 | 807
lung adenocarcinoma 5 | 2,716
primary pancreatic ductal adenocarcinoma 5 | 1,109
tuberculosis 5 | 2,010
Liver cancer 4 | 604
Wilson-Turner syndrome 4 | 14
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
pediatric high grade glioma 4 | 1,064
ulcerative colitis 4 | 1,819
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Intellectual disability 3 | 1,016
Polycystic ovary syndrome 3 | 360
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Sensorineural Hearing Loss (disorder) 3 | 284
Van Maldergem syndrome 3 | 5
medulloblastoma 3 | 720
Adenocarcinoma 2 | 122
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Carcinoma, Renal Cell 2 | 124
Cerebro-facio-articular syndrome 2 | 2
Duchenne muscular dystrophy 2 | 601
Dull intelligence 2 | 645
Epithelioid hemangioendothelioma 2 | 5
Esophageal Squamous Cell Carcinoma 2 | 77
Hennekam syndrome 2 | 7
Heterotopia, Periventricular, Autosomal Recessive 2 | 3
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Mesothelioma 2 | 38
Mesothelioma, Malignant 2 | 105
Nonorganic psychosis 2 | 84
Poor school performance 2 | 645
Psychotic Disorders 2 | 151
Skin cancer 2 | 469
Squamous cell carcinoma of esophagus 2 | 77
Van Maldergem Wetzburger Verloes syndrome 2 | 2
active ulcerative colitis 2 | 764
astrocytic glioma 2 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
Carcinoma, Non-Small-Cell Lung 1 | 107
Congenital hypoplasia of kidney 1 | 32
Decreased projection of midface 1 | 105
Hypospadias 1 | 53
Hypotrophic midface 1 | 105
Inflammatory Bowel Diseases 1 | 35
Meningioma 1 | 41
Midface retrusion 1 | 105
Mitral valve insufficiency 1 | 49
Nephroblastoma 1 | 51
Ovarian Neoplasms 1 | 102
Peripheral Neuropathy 1 | 134
Small midface 1 | 105
Squamous cell carcinoma of the head and neck 1 | 29
non-syndromic X-linked intellectual disability 1 | 20
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Cardiovascular System 26 | 15,192

Target Family

Non-IDG 17 | 12,091
Kinase 5 | 634
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145

KEGG Pathway

Hippo signaling pathway - mult... 28 | 28
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein KIBRA WWC1 Tbio Non-IDG -1.96854 92.8 130
LIM domain-containing protein ajuba AJUBA Tbio Non-IDG -1.15520 13.9 65
Protocadherin Fat 4 FAT4 Tbio Non-IDG -1.70369 49.6 50
Ras association domain-containing protein 4 RASSF4 Tbio Non-IDG -0.08831 1.60 110
Protocadherin-23 DCHS2 Tdark Non-IDG -0.44734 2.79 3
Wilms tumor protein 1-interacting protein WTIP Tbio Non-IDG -1.82042 59.4 59
LIM domain-containing protein 1 LIMD1 Tbio Non-IDG -1.18859 16.4 149
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Serine/threonine-protein kinase 3 STK3 Tchem Kinase -1.13339 11.3 303
MOB kinase activator 1B MOB1B Tbio Enzyme -0.76662 5.02 235