Development Level

Tbio 202 | 11,651
Tchem 39 | 1,388
Tclin 12 | 612
Tdark 9 | 6,593

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
enlarged heart 5 | 210
abnormal heart morphology 3 | 162
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
increased erythrocyte cell num... 3 | 39
increased leukocyte cell numbe... 3 | 47
increased lymphocyte cell numb... 3 | 32
increased neutrophil cell numb... 3 | 46
preweaning lethality, incomple... 3 | 499
abnormal coat-hair pigmentatio... 2 | 64
abnormal seminal vesicle morph... 2 | 114
decreased mean corpuscular vol... 2 | 79
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal skin condition 1 | 6
abnormal vibrissa morphology 1 | 25
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hypoactivity 1 | 132
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
limb grasping 1 | 41
male infertility 1 | 123
mammalian phenotype 1 | 17
short tibia 1 | 97
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Cancer 146 | 2,499
Carcinoma 140 | 11,493
psoriasis 132 | 6,694
ovarian cancer 99 | 8,520
diabetes mellitus 95 | 1,728
osteosarcoma 93 | 7,950
Rheumatoid arthritis 88 | 1,191
Hypersensitivity reaction type II disease 84 | 253
Arthritis 83 | 290
lung cancer 82 | 4,740
glioblastoma 77 | 5,792
Ankylosing spondylitis 73 | 140
Behcet's disease 70 | 89
Juvenile rheumatoid arthritis 68 | 111
Acquired immunodeficiency syndrome 63 | 197
Multiple Sclerosis 63 | 540
Uveitis 62 | 103
tuberculosis 62 | 2,010
dermatomyositis 61 | 966
Human immunodeficiency virus infectious disease 60 | 138
Herpes zoster 58 | 68
Stevens-Johnson syndrome 57 | 92
Psoriatic arthritis 55 | 86
medulloblastoma, large-cell 53 | 6,241
Astrocytoma, Pilocytic 44 | 3,081
Dermatitis 44 | 157
adult high grade glioma 44 | 3,801
ependymoma 43 | 4,679
lung carcinoma 43 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
malignant mesothelioma 41 | 3,232
subependymal giant cell astrocytoma 41 | 2,287
Breast cancer 40 | 3,578
Liver disease 40 | 237
Synovitis 40 | 78
atypical teratoid / rhabdoid tumor 40 | 5,112
non-small cell lung cancer 40 | 2,890
Takayasu's arteritis 39 | 53
invasive ductal carcinoma 39 | 2,951
Behcet's syndrome 38 | 50
Hepatitis B 38 | 108
Kidney disease 38 | 430
Schizophrenia 38 | 1,160
Nephritis 36 | 51
Congenital adrenal hyperplasia 35 | 73
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
cutaneous lupus erythematosus 35 | 1,057
drug-induced hepatitis 35 | 44
juvenile dermatomyositis 35 | 1,187
Anemia 34 | 365
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
lung adenocarcinoma 32 | 2,716
Multiple myeloma 30 | 1,332
Systemic lupus erythematosus 30 | 194
Leprosy 29 | 73
cystic fibrosis 29 | 1,696
interstitial cystitis 29 | 2,312
pancreatic cancer 28 | 2,398
Kidney cancer 27 | 2,613
Primary immunodeficiency disease 27 | 54
Asthma 26 | 385
Skin disease 26 | 66
breast carcinoma 26 | 1,638
Influenza 25 | 142
astrocytoma 25 | 1,146
group 4 medulloblastoma 25 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
primary Sjogren syndrome 24 | 735
Hemochromatosis 23 | 54
sarcoidosis 23 | 370
ulcerative colitis 22 | 1,819
Birdshot chorioretinopathy 21 | 23
Obesity 21 | 678
group 3 medulloblastoma 21 | 4,104
Bipolar Disorder 20 | 666
active Crohn's disease 20 | 922
colon cancer 20 | 1,478
pituitary cancer 20 | 1,972
Inflammatory bowel disease 19 | 151
Waldenstrons macroglobulinemia 19 | 765
active ulcerative colitis 19 | 764
Brain Ischemia 18 | 110
Narcolepsy 18 | 72
adrenocortical carcinoma 18 | 1,428
hepatocellular carcinoma 18 | 547
primitive neuroectodermal tumor 18 | 3,035
Autosomal recessive predisposition 17 | 1,442
Berylliosis 17 | 28
Human immunodeficiency virus type 1, susceptibility to 17 | 26
Intellectual disability 17 | 1,016
Liver Cirrhosis, Experimental 17 | 769
Vasculitis 17 | 80
Depressive disorder 16 | 409
Endometriosis 16 | 540
Mammary Neoplasms 16 | 425
Vascular disease 16 | 319
nasopharyngeal carcinoma 16 | 1,058
oligodendroglioma 16 | 2,850

Tissue

Blood and immune system 166 | 16,909
Male tissues 164 | 17,142
Respiratory system 164 | 16,393
Digestive Tract 163 | 17,369
Endocrine System 163 | 18,159
Female tissues 163 | 17,400
Urinary Tract 162 | 16,678
Liver and Pancreas 161 | 16,750
Skin and soft tissues 161 | 17,230
Nervous System 159 | 16,725
Cardiovascular System 154 | 15,192

Target Family

Non-IDG 199 | 12,091
Kinase 25 | 634
Enzyme 19 | 4,145
Transcription Factor 14 | 1,400
Epigenetic 3 | 242
TF/Epigenetic 2 | 38

KEGG Pathway

Herpes simplex infection 262 | 262
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tbio Non-IDG -2.81111 643.5 577
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L TAF6L Tdark Enzyme 0.55 0.23 173
HLA class I histocompatibility antigen, B-37 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Paired immunoglobulin-like type 2 receptor alpha PILRA Tbio Non-IDG -1.07300 11.4 105
Host cell factor 2 HCFC2 Tbio Non-IDG -0.75967 5.45 102
Interferon gamma receptor 1 IFNGR1 Tbio Non-IDG -2.23009 172.7 518