Development Level

Tbio 193 | 11,178
Tchem 48 | 1,885
Tclin 12 | 612
Tdark 9 | 6,569

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
enlarged heart 5 | 210
abnormal heart morphology 3 | 162
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
increased erythrocyte cell num... 3 | 39
increased leukocyte cell numbe... 3 | 47
increased lymphocyte cell numb... 3 | 32
increased neutrophil cell numb... 3 | 46
preweaning lethality, incomple... 3 | 499
abnormal coat-hair pigmentatio... 2 | 64
abnormal seminal vesicle morph... 2 | 114
decreased mean corpuscular vol... 2 | 79
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal skin condition 1 | 6
abnormal vibrissa morphology 1 | 25
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hypoactivity 1 | 132
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
limb grasping 1 | 41
male infertility 1 | 123
mammalian phenotype 1 | 17
short tibia 1 | 97
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Cancer 142 | 2,388
Carcinoma 138 | 11,192
psoriasis 130 | 6,514
ovarian cancer 96 | 8,297
diabetes mellitus 93 | 1,683
osteosarcoma 92 | 7,766
Rheumatoid arthritis 86 | 1,156
Hypersensitivity reaction type II disease 84 | 245
Arthritis 82 | 276
lung cancer 79 | 4,607
glioblastoma 75 | 5,635
Ankylosing spondylitis 73 | 134
Behcet's disease 70 | 87
Juvenile rheumatoid arthritis 68 | 110
Acquired immunodeficiency syndrome 63 | 192
Multiple Sclerosis 63 | 527
Uveitis 62 | 102
tuberculosis 62 | 1,963
dermatomyositis 61 | 941
Human immunodeficiency virus infectious disease 60 | 136
Herpes zoster 58 | 68
Stevens-Johnson syndrome 57 | 92
Psoriatic arthritis 55 | 84
medulloblastoma, large-cell 52 | 6,086
Dermatitis 44 | 154
adult high grade glioma 43 | 3,701
Astrocytoma, Pilocytic 42 | 3,006
ependymoma 42 | 4,559
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,204
lung carcinoma 41 | 2,755
Liver disease 40 | 227
Synovitis 40 | 75
malignant mesothelioma 40 | 3,135
Takayasu's arteritis 39 | 53
subependymal giant cell astrocytoma 39 | 2,230
Behcet's syndrome 38 | 49
Breast cancer 38 | 3,469
Hepatitis B 38 | 105
atypical teratoid / rhabdoid tumor 38 | 4,971
invasive ductal carcinoma 38 | 2,867
non-small cell lung cancer 38 | 2,799
Kidney disease 37 | 411
Nephritis 36 | 51
Schizophrenia 36 | 1,136
Congenital adrenal hyperplasia 35 | 71
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
cutaneous lupus erythematosus 35 | 1,016
drug-induced hepatitis 35 | 44
Anemia 34 | 353
juvenile dermatomyositis 34 | 1,147
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,902
lung adenocarcinoma 31 | 2,627
Multiple myeloma 30 | 1,296
Systemic lupus erythematosus 30 | 191
Leprosy 29 | 72
cystic fibrosis 29 | 1,629
interstitial cystitis 28 | 2,237
pancreatic cancer 28 | 2,322
Primary immunodeficiency disease 27 | 54
Asthma 26 | 370
Skin disease 26 | 64
Influenza 25 | 136
Kidney cancer 25 | 2,548
breast carcinoma 25 | 1,589
astrocytoma 24 | 1,113
Hemochromatosis 23 | 52
group 4 medulloblastoma 23 | 1,806
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,872
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,911
primary Sjogren syndrome 23 | 710
sarcoidosis 23 | 357
Birdshot chorioretinopathy 21 | 22
group 3 medulloblastoma 21 | 4,002
ulcerative colitis 21 | 1,765
Bipolar Disorder 19 | 646
Inflammatory bowel disease 19 | 148
Obesity 19 | 655
active Crohn's disease 19 | 882
colon cancer 19 | 1,428
pituitary cancer 19 | 1,915
Brain Ischemia 18 | 107
Waldenstrons macroglobulinemia 18 | 742
active ulcerative colitis 18 | 736
Autosomal recessive predisposition 17 | 1,407
Berylliosis 17 | 26
Human immunodeficiency virus type 1, susceptibility to 17 | 26
Narcolepsy 17 | 70
Vasculitis 17 | 76
hepatocellular carcinoma 17 | 536
primitive neuroectodermal tumor 17 | 2,957
Intellectual disability 16 | 998
Vascular disease 16 | 294
nasopharyngeal carcinoma 16 | 1,024
oligodendroglioma 16 | 2,768
Arthritis, Rheumatoid 15 | 169
Endometriosis 15 | 521
Liver Cirrhosis, Experimental 15 | 733
Lung disease 15 | 135
adrenocortical carcinoma 15 | 1,385

Tissue

Blood and immune system 166 | 16,909
Male tissues 164 | 17,142
Respiratory system 164 | 16,393
Digestive Tract 163 | 17,369
Endocrine System 163 | 18,159
Female tissues 163 | 17,400
Urinary Tract 162 | 16,678
Liver and Pancreas 161 | 16,750
Skin and soft tissues 161 | 17,230
Nervous System 159 | 16,725
Cardiovascular System 154 | 15,192

Target Family

Non-IDG 199 | 12,091
Kinase 25 | 634
Enzyme 19 | 4,145
Transcription Factor 14 | 1,400
Epigenetic 3 | 242
TF/Epigenetic 2 | 38

KEGG Pathway

Herpes simplex infection 262 | 262
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, B-67 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 362
2-5A-dependent ribonuclease RNASEL Tchem Kinase -2.71673 525.8 127
Microspherule protein 1 MCRS1 Tbio Non-IDG -1.40659 32.1 99
Interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2 Tbio Kinase -1.96184 89.9 894
HLA class I histocompatibility antigen, Cw-16 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0
HLA class I histocompatibility antigen, B-59 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Serine/arginine-rich splicing factor 7 SRSF7 Tbio Non-IDG -1.19691 12.9 177