Development Level

Tbio 192 | 10,625
Tchem 48 | 1,890
Tclin 12 | 602
Tdark 10 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 7 | 633
increased circulating alkaline... 3 | 119
abnormal coat/hair pigmentatio... 2 | 54
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
decreased monocyte cell number 2 | 28
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
increased leukocyte cell numbe... 2 | 37
preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal skin condition 1 | 6
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased circulating amylase ... 1 | 24
decreased circulating sodium l... 1 | 18
decreased grip strength 1 | 123
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased thermal nociceptive ... 1 | 4
enlarged lymph nodes 1 | 27
hypoactivity 1 | 89
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased body weight 1 | 42
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased lymphocyte cell numb... 1 | 9
increased mature B cell number 1 | 12
increased neutrophil cell numb... 1 | 15
increased thermal nociceptive ... 1 | 9
limb grasping 1 | 35
polydactyly 1 | 22
small superior vagus ganglion 1 | 20
vertebral fusion 1 | 23

Disease

Cancer 145 | 2,346
psoriasis 130 | 6,685
ovarian cancer 99 | 8,492
diabetes mellitus 93 | 1,663
osteosarcoma 93 | 7,933
Rheumatoid Arthritis 86 | 1,171
Hypersensitivity reaction type II disease 83 | 235
lung cancer 80 | 4,473
Arthritis 78 | 248
glioblastoma 74 | 5,572
Ankylosing spondylitis 73 | 138
Juvenile rheumatoid arthritis 65 | 105
dermatomyositis 64 | 967
Acquired immunodeficiency syndrome 63 | 164
Multiple Sclerosis 63 | 498
Uveitis 60 | 103
Human immunodeficiency virus infectious disease 57 | 129
Stevens-Johnson syndrome 57 | 91
Behcet's disease 56 | 74
Psoriatic arthritis 56 | 85
medulloblastoma, large-cell 53 | 6,234
pilocytic astrocytoma 45 | 3,086
Dermatitis 44 | 141
lung carcinoma 43 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
subependymal giant cell astrocytoma 41 | 2,287
non-small cell lung cancer 40 | 2,798
Synovitis 39 | 72
Takayasu's arteritis 39 | 54
invasive ductal carcinoma 39 | 2,950
Behcet's syndrome 38 | 50
Kidney disease 38 | 397
malignant mesothelioma 38 | 3,163
Liver disease 37 | 219
Nephritis 37 | 63
Hepatitis B 36 | 103
tuberculosis 36 | 1,563
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
atypical teratoid / rhabdoid tumor 35 | 4,369
cutaneous lupus erythematosus 35 | 1,056
drug-induced hepatitis 35 | 44
juvenile dermatomyositis 35 | 1,189
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,988
Anemia 32 | 252
Breast cancer 32 | 3,099
astrocytoma 32 | 1,493
lung adenocarcinoma 32 | 2,714
Multiple myeloma 30 | 1,328
ulcerative colitis 30 | 2,087
cystic fibrosis 29 | 1,670
interstitial cystitis 29 | 2,299
posterior fossa group A ependymoma 29 | 1,511
systemic lupus erythematosus 29 | 172
Leprosy 28 | 77
pancreatic cancer 28 | 2,300
pediatric high grade glioma 28 | 2,712
primary Sjogren syndrome 28 | 789
Primary immunodeficiency disease 27 | 52
Influenza 26 | 142
Skin disease 26 | 65
breast carcinoma 25 | 1,614
adult high grade glioma 24 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
Asthma 23 | 349
Hemochromatosis 23 | 55
group 4 medulloblastoma 23 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,795
sarcoidosis 23 | 368
Birdshot chorioretinopathy 21 | 23
Carcinoma 20 | 2,147
active Crohn's disease 20 | 918
colon cancer 20 | 1,475
ependymoma 20 | 2,514
pituitary cancer 20 | 1,972
Waldenstrons macroglobulinemia 19 | 765
Narcolepsy 18 | 69
adrenocortical carcinoma 18 | 1,427
hepatocellular carcinoma 18 | 550
primitive neuroectodermal tumor 18 | 3,031
Berylliosis 17 | 28
Human immunodeficiency virus type 1, susceptibility to 17 | 26
Endometriosis 16 | 535
Mammary Neoplasms 16 | 410
nasopharyngeal carcinoma 16 | 1,056
oligodendroglioma 16 | 2,849
Inflammatory bowel disease 15 | 142
Lung disease 15 | 136
Obesity 15 | 616
Reperfusion Injury 15 | 84
pre-eclampsia 15 | 67
Brain Ischemia 14 | 87
Hepatitis C 14 | 90
Intellectual disability 14 | 573
Narcolepsy-cataplexy 14 | 21
Rheumatoid Arthritis, Systemic Juvenile 14 | 16
Vascular disease 14 | 281
esophageal adenocarcinoma 14 | 737
pancreatic carcinoma 14 | 567

Tissue

Nervous System 188 | 18,561
Digestive Tract 187 | 18,473
Female tissues 187 | 18,647
Urinary Tract 187 | 18,444
Blood and immune system 184 | 17,995
Endocrine System 181 | 18,512
Liver and Pancreas 181 | 18,136
Cardiovascular System 178 | 17,958
Respiratory system 177 | 17,484
Male tissues 176 | 17,969
Skin and soft tissues 169 | 18,115

Target Family

Non-IDG 199 | 11,969
Kinase 25 | 634
Enzyme 19 | 4,146
Transcription Factor 14 | 1,400
Epigenetic 3 | 242
TF/Epigenetic 2 | 38

KEGG Pathway

Herpes simplex infection 262 | 262
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.07995 1275.9 729
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.22244 1606.1 561
THO complex subunit 4 ALYREF Tbio Non-IDG -2.43751 263.2 0
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.67984 438.1 349
2'-5'-oligoadenylate synthase 2 OAS2 Tbio Enzyme -1.36819 16.7 185
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274
Serine/threonine-protein kinase TBK1 TBK1 Tchem Kinase -2.73611 447.9 420
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -2.40709 4042.7 585
General transcription factor II-I repeat domain-containing protein 1 GTF2IRD1 Tbio Transcription Factor -1.68816 0.00000 253
Caspase-8 CASP8 Tchem Enzyme -3.51864 2954.7 930