Development Level

Tbio 61 | 10,625
Tchem 50 | 1,890
Tclin 12 | 602
Tdark 9 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
decreased lean body mass 3 | 195
decreased body weight 2 | 174
decreased circulating creatini... 2 | 31
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
enlarged heart 2 | 111
enlarged spleen 2 | 26
increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased hematocrit 2 | 36
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal glucose homeostasis 1 | 5
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal respiratory quotient 1 | 9
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 5
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased thermal nociceptive ... 1 | 4
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
enlarged lymph nodes 1 | 27
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased circulating LDL chol... 1 | 15
increased circulating free fat... 1 | 17
increased erythrocyte cell num... 1 | 26
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased neutrophil cell numb... 1 | 15
increased thermal nociceptive ... 1 | 9
male infertility 1 | 62
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
shortened RR interval 1 | 19
small testis 1 | 37
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

ovarian cancer 79 | 8,484
Cancer 70 | 2,346
psoriasis 65 | 6,685
osteosarcoma 64 | 7,933
glioblastoma 53 | 5,572
medulloblastoma, large-cell 47 | 6,234
atypical teratoid / rhabdoid tumor 45 | 4,369
lung cancer 44 | 4,466
Breast cancer 34 | 3,094
invasive ductal carcinoma 32 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
pilocytic astrocytoma 31 | 3,086
pancreatic cancer 30 | 2,300
subependymal giant cell astrocytoma 29 | 2,287
lung adenocarcinoma 26 | 2,713
ependymoma 25 | 2,514
interstitial cystitis 25 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
juvenile dermatomyositis 24 | 1,189
cystic fibrosis 23 | 1,665
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
Multiple Sclerosis 22 | 498
ductal carcinoma in situ 22 | 1,745
ulcerative colitis 22 | 2,087
Carcinoma 21 | 2,147
Rheumatoid Arthritis 21 | 1,160
malignant mesothelioma 21 | 3,162
pediatric high grade glioma 21 | 2,712
diabetes mellitus 20 | 1,663
lung carcinoma 20 | 2,844
non-small cell lung cancer 20 | 2,798
Mammary Neoplasms 19 | 410
Prostatic Neoplasms 19 | 471
medulloblastoma 19 | 1,524
oligodendroglioma 19 | 2,849
Influenza 18 | 142
pituitary cancer 18 | 1,972
Hepatitis C 17 | 90
astrocytoma 17 | 1,493
tuberculosis 17 | 1,557
Lung Neoplasms 16 | 171
Multiple myeloma 16 | 1,327
Vascular disease 16 | 281
cutaneous lupus erythematosus 16 | 1,056
group 4 medulloblastoma 16 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
Arthritis 15 | 248
Stomach Neoplasms 15 | 282
adult high grade glioma 15 | 2,148
breast carcinoma 15 | 1,614
dermatomyositis 15 | 933
primary pancreatic ductal adenocarcinoma 14 | 1,271
primitive neuroectodermal tumor 14 | 3,031
Inflammatory bowel disease 13 | 142
Pick disease 13 | 1,893
pancreatic carcinoma 13 | 567
primary Sjogren syndrome 13 | 789
Atopic dermatitis 12 | 944
Brain Ischemia 12 | 87
Lung disease 12 | 132
active Crohn's disease 12 | 918
astrocytic glioma 12 | 2,241
nasopharyngeal carcinoma 12 | 1,056
Asthma 11 | 349
Liver disease 11 | 219
Obesity 11 | 616
Squamous cell carcinoma 11 | 94
non-small cell lung carcinoma 11 | 413
Colorectal Neoplasms 10 | 217
Kidney disease 10 | 396
Liver carcinoma 10 | 217
Renal Cell Carcinoma 10 | 199
Reperfusion Injury 10 | 84
Schizophrenia 10 | 501
adrenocortical carcinoma 10 | 1,427
spina bifida 10 | 1,064
systemic lupus erythematosus 10 | 156
Adenocarcinoma 9 | 115
Alzheimer's disease 9 | 644
Atherosclerosis 9 | 275
Diarrhea 9 | 155
Heart disease 9 | 279
Hepatitis 9 | 61
Hepatitis B 9 | 103
Hypersensitivity reaction type II disease 9 | 235
Liver neoplasms 9 | 109
Melanoma 9 | 261
Neoplasm Metastasis 9 | 138
Neoplastic Cell Transformation 9 | 81
group 3 medulloblastoma 9 | 2,254
hepatocellular carcinoma 9 | 532
posterior fossa group A ependymoma 9 | 1,511
tuberculosis and treatment for 6 months 9 | 686
Adenoma 8 | 165
Colonic Neoplasms 8 | 126
Endometriosis 8 | 535
Pancreatic Neoplasm 8 | 79
acute myeloid leukemia 8 | 780
colon cancer 8 | 1,475
gastric carcinoma 8 | 832

Tissue

Nervous System 131 | 18,561
Digestive Tract 129 | 18,473
Female tissues 129 | 18,647
Urinary Tract 128 | 18,444
Skin and soft tissues 126 | 18,115
Endocrine System 125 | 18,512
Blood and immune system 123 | 17,995
Liver and Pancreas 122 | 18,136
Cardiovascular System 121 | 17,958
Respiratory system 119 | 17,484
Male tissues 116 | 17,969

Target Family

Non-IDG 63 | 11,971
Kinase 36 | 634
Enzyme 19 | 4,146
Transcription Factor 11 | 1,400
Nuclear Receptor 3 | 48

KEGG Pathway

Hepatitis C 132 | 132
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Interferon regulatory factor 9 IRF9 Tbio Transcription Factor -1.79340 61.7 168
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform PPP2R2A Tchem Enzyme -1.29353 14.5 115
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
Eukaryotic translation initiation factor 3 subunit E EIF3E Tbio Non-IDG -1.39943 28.0 202
Interferon alpha/beta receptor 2 IFNAR2 Tclin Non-IDG -1.87993 74.0 225
Claudin-3 CLDN3 Tbio Non-IDG -2.30333 205.5 260
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181