Development Level
Tbio | 68 | 11,445 | |
Tchem | 60 | 1,598 | |
Tclin | 13 | 613 | |
Tdark | 2 | 6,588 |
IMPC Phenotype
preweaning lethality, incomple... | 8 | 499 | |
preweaning lethality, complete... | 7 | 979 | |
edema | 4 | 59 | |
abnormal embryo size | 3 | 220 | |
decreased body weight | 3 | 161 | |
enlarged lymph nodes | 3 | 37 | |
increased circulating alkaline... | 3 | 122 | |
short tibia | 3 | 97 | |
small superior vagus ganglion | 3 | 74 | |
abnormal gait | 2 | 69 | |
abnormal heart morphology | 2 | 162 | |
abnormal neural tube closure | 2 | 46 | |
abnormal retina morphology | 2 | 71 | |
abnormal testis morphology | 2 | 43 | |
decreased circulating creatini... | 2 | 39 | |
decreased circulating sodium l... | 2 | 22 | |
decreased mean corpuscular vol... | 2 | 79 | |
embryonic lethality prior to t... | 2 | 278 | |
increased circulating choleste... | 2 | 66 | |
increased circulating free fat... | 2 | 20 | |
increased neutrophil cell numb... | 2 | 46 | |
abnormal behavior | 1 | 298 | |
abnormal bone mineralization | 1 | 38 | |
abnormal bone structure | 1 | 187 | |
abnormal cecum morphology | 1 | 7 | |
abnormal coat appearance | 1 | 31 | |
abnormal cornea morphology | 1 | 31 | |
abnormal epididymis morphology | 1 | 42 | |
abnormal eye morphology | 1 | 68 | |
abnormal femur morphology | 1 | 14 | |
abnormal forebrain development | 1 | 20 | |
abnormal glucose homeostasis | 1 | 4 | |
abnormal hindbrain development | 1 | 16 | |
abnormal lens morphology | 1 | 81 | |
abnormal lung morphology | 1 | 26 | |
abnormal midbrain development | 1 | 20 | |
abnormal pericardium morpholog... | 1 | 26 | |
abnormal seminal vesicle morph... | 1 | 114 | |
abnormal skin coloration | 1 | 25 | |
abnormal skin condition | 1 | 6 | |
abnormal skin morphology | 1 | 50 | |
abnormal spleen morphology | 1 | 55 | |
abnormal startle reflex | 1 | 15 | |
abnormal vibrissa morphology | 1 | 25 | |
cataract | 1 | 92 | |
decreased bone mineral content | 1 | 151 | |
decreased circulating LDL chol... | 1 | 38 | |
decreased circulating amylase ... | 1 | 28 | |
decreased circulating aspartat... | 1 | 34 | |
decreased circulating choleste... | 1 | 93 | |
decreased circulating fructosa... | 1 | 30 | |
decreased circulating insulin ... | 1 | 76 | |
decreased circulating triglyce... | 1 | 79 | |
decreased eosinophil cell numb... | 1 | 24 | |
decreased fasted circulating g... | 1 | 65 | |
decreased heart left ventricle... | 1 | 28 | |
decreased heart weight | 1 | 27 | |
decreased lymphocyte cell numb... | 1 | 83 | |
decreased mean corpuscular hem... | 1 | 31 | |
decreased thermal nociceptive ... | 1 | 2 | |
decreased total body fat amoun... | 1 | 207 | |
embryonic growth retardation | 1 | 106 | |
embryonic lethality prior to o... | 1 | 239 | |
enlarged cecum | 1 | 5 | |
enlarged epididymis | 1 | 31 | |
enlarged heart | 1 | 210 | |
enlarged heart atrium | 1 | 4 | |
enlarged spleen | 1 | 41 | |
enlarged uterus | 1 | 11 | |
female infertility | 1 | 60 | |
hyperactivity | 1 | 148 | |
impaired righting response | 1 | 26 | |
increased bone mineral content | 1 | 108 | |
increased bone mineral density | 1 | 72 | |
increased circulating HDL chol... | 1 | 80 | |
increased circulating LDL chol... | 1 | 13 | |
increased circulating glucose ... | 1 | 24 | |
increased eosinophil cell numb... | 1 | 11 | |
increased erythrocyte cell num... | 1 | 39 | |
increased hematocrit | 1 | 46 | |
increased hemoglobin content | 1 | 45 | |
increased lean body mass | 1 | 172 | |
increased leukocyte cell numbe... | 1 | 47 | |
increased lymphocyte cell numb... | 1 | 32 | |
increased mean corpuscular hem... | 1 | 96 | |
increased mean corpuscular vol... | 1 | 92 | |
increased or absent threshold ... | 1 | 101 | |
increased thermal nociceptive ... | 1 | 9 | |
increased total body fat amoun... | 1 | 134 | |
male infertility | 1 | 123 | |
microphthalmia | 1 | 26 | |
prenatal lethality | 1 | 28 | |
small seminal vesicle | 1 | 10 | |
small testis | 1 | 58 | |
thrombocytosis | 1 | 27 |
Disease
Tissue
Blood and immune system | 132 | 16,909 | |
Male tissues | 130 | 17,142 | |
Nervous System | 130 | 16,725 | |
Digestive Tract | 129 | 17,369 | |
Endocrine System | 129 | 18,159 | |
Female tissues | 129 | 17,400 | |
Liver and Pancreas | 129 | 16,750 | |
Skin and soft tissues | 129 | 17,230 | |
Urinary Tract | 129 | 16,678 | |
Respiratory system | 127 | 16,393 | |
Cardiovascular System | 125 | 15,192 |
Target Family
Non-IDG | 52 | 12,091 | |
Transcription Factor | 37 | 1,400 | |
Kinase | 32 | 634 | |
Enzyme | 20 | 4,145 | |
Epigenetic | 2 | 242 |
KEGG Pathway
Hepatitis B | 143 | 143 | |
Metabolic pathways | 1,263 | 1,263 | |
Pathways in cancer | 530 | 530 | |
Olfactory transduction | 414 | 414 | |
Human papillomavirus infection | 388 | 388 | |
PI3K-Akt signaling pathway | 349 | 349 | |
HTLV-I infection | 336 | 336 | |
Endocytosis | 310 | 310 | |
MAPK signaling pathway | 295 | 295 | |
Epstein-Barr virus infection | 280 | 280 | |
Neuroactive ligand-receptor in... | 276 | 276 | |
Cytokine-cytokine receptor int... | 267 | 267 | |
Herpes simplex infection | 262 | 262 | |
Kaposi's sarcoma-associated he... | 252 | 252 | |
Viral carcinogenesis | 251 | 251 | |
Thermogenesis | 232 | 232 | |
Ras signaling pathway | 230 | 230 | |
Phagosome | 229 | 229 | |
Cellular senescence | 228 | 228 | |
Cell adhesion molecules (CAMs) | 225 | 225 | |
Rap1 signaling pathway | 209 | 209 | |
Regulation of actin cytoskelet... | 207 | 207 | |
cAMP signaling pathway | 201 | 201 | |
Focal adhesion | 198 | 198 | |
Proteoglycans in cancer | 198 | 198 | |
Natural killer cell mediated c... | 197 | 197 | |
Huntington's disease | 194 | 194 | |
Tuberculosis | 189 | 189 | |
Calcium signaling pathway | 183 | 183 | |
Chemokine signaling pathway | 183 | 183 | |
Influenza A | 182 | 182 | |
Axon guidance | 174 | 174 | |
Purine metabolism | 172 | 172 | |
Alzheimer's disease | 171 | 171 | |
Transcriptional misregulation ... | 171 | 171 | |
Tight junction | 169 | 169 | |
Hepatocellular carcinoma | 168 | 168 | |
NOD-like receptor signaling pa... | 166 | 166 | |
Protein processing in endoplas... | 164 | 164 | |
RNA transport | 163 | 163 | |
cGMP-PKG signaling pathway | 162 | 162 | |
Jak-STAT signaling pathway | 161 | 161 | |
Cushing's syndrome | 158 | 158 | |
Antigen processing and present... | 156 | 156 | |
Hippo signaling pathway | 154 | 154 | |
Necroptosis | 154 | 154 | |
Oxytocin signaling pathway | 154 | 154 | |
MicroRNAs in cancer | 150 | 150 | |
mTOR signaling pathway | 150 | 150 | |
Non-alcoholic fatty liver dise... | 149 | 149 | |
Gastric cancer | 148 | 148 | |
Retrograde endocannabinoid sig... | 148 | 148 | |
Adrenergic signaling in cardio... | 147 | 147 | |
Alcoholism | 147 | 147 | |
Breast cancer | 147 | 147 | |
Phospholipase D signaling path... | 147 | 147 | |
Wnt signaling pathway | 145 | 145 | |
Parkinson's disease | 142 | 142 | |
Estrogen signaling pathway | 139 | 139 | |
Apoptosis | 138 | 138 | |
Fluid shear stress and atheros... | 138 | 138 | |
Signaling pathways regulating ... | 138 | 138 | |
Insulin signaling pathway | 137 | 137 | |
Ubiquitin mediated proteolysis | 137 | 137 | |
Viral myocarditis | 137 | 137 | |
Apelin signaling pathway | 136 | 136 | |
Dopaminergic synapse | 135 | 135 | |
Ribosome | 134 | 134 | |
Measles | 133 | 133 | |
Oxidative phosphorylation | 133 | 133 | |
Relaxin signaling pathway | 133 | 133 | |
Spliceosome | 132 | 132 | |
Autoimmune thyroid disease | 130 | 130 | |
FoxO signaling pathway | 130 | 130 | |
Hepatitis C | 130 | 130 | |
Autophagy - animal | 128 | 128 | |
Osteoclast differentiation | 127 | 127 | |
Cell cycle | 125 | 125 | |
Platelet activation | 125 | 125 | |
Toxoplasmosis | 125 | 125 | |
Lysosome | 123 | 123 | |
Vascular smooth muscle contrac... | 123 | 123 | |
Type I diabetes mellitus | 122 | 122 | |
Oocyte meiosis | 121 | 121 | |
AMPK signaling pathway | 120 | 120 | |
Graft-versus-host disease | 120 | 120 | |
Neurotrophin signaling pathway | 119 | 119 | |
Th17 cell differentiation | 119 | 119 | |
Sphingolipid signaling pathway | 118 | 118 | |
Allograft rejection | 116 | 116 | |
Carbon metabolism | 116 | 116 | |
Glutamatergic synapse | 116 | 116 | |
Thyroid hormone signaling path... | 116 | 116 | |
Serotonergic synapse | 114 | 114 | |
Leukocyte transendothelial mig... | 112 | 112 | |
Cholinergic synapse | 111 | 111 | |
Hematopoietic cell lineage | 108 | 108 | |
Systemic lupus erythematosus | 108 | 108 | |
TNF signaling pathway | 108 | 108 | |
Insulin resistance | 107 | 107 |
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