Development Level

Tbio 232 | 10,625
Tchem 82 | 1,890
Tclin 22 | 602
Tdark 3 | 7,003

Collection

Eligible Kinase Proteins 3 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 17 | 633
embryonic lethality prior to t... 7 | 187
preweaning lethality, incomple... 7 | 260
increased circulating alkaline... 6 | 119
abnormal embryo size 5 | 112
embryonic lethality prior to o... 5 | 148
abnormal bone mineralization 4 | 55
decreased grip strength 4 | 123
enlarged heart 4 | 111
hydrops fetalis 4 | 22
abnormal cornea morphology 3 | 24
abnormal lens morphology 3 | 73
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased circulating chloride... 3 | 32
decreased circulating choleste... 3 | 85
decreased circulating sodium l... 3 | 18
decreased circulating triglyce... 3 | 83
decreased lean body mass 3 | 195
increased bone mineral density 3 | 52
increased grip strength 3 | 83
male infertility 3 | 62
short tibia 3 | 82
abnormal bone structure 2 | 131
abnormal eye morphology 2 | 38
abnormal forebrain development 2 | 18
abnormal heart morphology 2 | 51
abnormal hindbrain development 2 | 24
abnormal neural tube closure 2 | 37
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
abnormal startle reflex 2 | 14
cataract 2 | 26
decreased T cell number 2 | 31
decreased body length 2 | 108
decreased caudal vertebrae num... 2 | 49
decreased circulating alanine ... 2 | 53
decreased circulating aspartat... 2 | 27
decreased circulating creatini... 2 | 31
decreased circulating fructosa... 2 | 31
decreased circulating glucose ... 2 | 121
decreased circulating glycerol... 2 | 19
decreased lumbar vertebrae num... 2 | 62
decreased monocyte cell number 2 | 28
decreased startle reflex 2 | 48
female infertility 2 | 34
immune system phenotype 2 | 17
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased circulating choleste... 2 | 53
increased circulating triglyce... 2 | 24
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular vol... 2 | 91
microphthalmia 2 | 15
prenatal lethality prior to he... 2 | 64
abnormal epididymis morphology 1 | 31
abnormal eye size 1 | 11
abnormal facial morphology 1 | 9
abnormal head morphology 1 | 10
abnormal optic disc morphology 1 | 10
abnormal respiratory quotient 1 | 9
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
cleft palate 1 | 6
corneal opacity 1 | 25
cyanosis 1 | 6
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased IgG1 level 1 | 4
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating serum al... 1 | 79
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased hematocrit 1 | 25
decreased mean corpuscular hem... 1 | 19
embryonic growth retardation 1 | 28
enlarged spleen 1 | 26
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased caudal vertebrae num... 1 | 8
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased effector memory CD4-... 1 | 15
increased eosinophil cell numb... 1 | 9
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107
increased startle reflex 1 | 38
limb grasping 1 | 35
prenatal lethality 1 | 16
small testis 1 | 37
thrombocytosis 1 | 23
vertebral fusion 1 | 23

Disease

Cancer 213 | 2,346
psoriasis 160 | 6,685
ovarian cancer 151 | 8,484
osteosarcoma 129 | 7,933
lung cancer 110 | 4,466
glioblastoma 108 | 5,572
diabetes mellitus 105 | 1,663
medulloblastoma, large-cell 98 | 6,234
Rheumatoid Arthritis 80 | 1,160
malignant mesothelioma 76 | 3,162
Ankylosing spondylitis 75 | 138
Hypersensitivity reaction type II disease 75 | 235
Breast cancer 74 | 3,094
Arthritis 71 | 248
atypical teratoid / rhabdoid tumor 68 | 4,369
Juvenile rheumatoid arthritis 66 | 104
Acquired immunodeficiency syndrome 65 | 164
invasive ductal carcinoma 64 | 2,950
lung carcinoma 63 | 2,844
non-small cell lung cancer 63 | 2,798
pilocytic astrocytoma 63 | 3,086
Uveitis 60 | 103
Behcet's disease 56 | 74
lung adenocarcinoma 56 | 2,713
oligodendroglioma 56 | 2,849
Psoriatic arthritis 54 | 83
primitive neuroectodermal tumor 54 | 3,031
interstitial cystitis 53 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 53 | 2,988
subependymal giant cell astrocytoma 53 | 2,287
astrocytoma 52 | 1,493
pediatric high grade glioma 52 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,289
ulcerative colitis 51 | 2,087
Multiple Sclerosis 49 | 498
pancreatic cancer 49 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,956
Carcinoma 45 | 2,147
posterior fossa group A ependymoma 44 | 1,511
breast carcinoma 43 | 1,614
adrenocortical carcinoma 42 | 1,427
ependymoma 42 | 2,514
ductal carcinoma in situ 41 | 1,745
group 3 medulloblastoma 41 | 2,254
tuberculosis 41 | 1,557
Kidney disease 40 | 396
Stevens-Johnson syndrome 40 | 78
Takayasu's arteritis 37 | 52
colon cancer 37 | 1,475
juvenile dermatomyositis 36 | 1,189
Congenital adrenal hyperplasia 35 | 74
Liver disease 35 | 219
Retinal vasculitis 35 | 36
cystic fibrosis 35 | 1,665
adult high grade glioma 33 | 2,148
group 4 medulloblastoma 33 | 1,875
pituitary cancer 33 | 1,972
Mammary Neoplasms 32 | 410
cutaneous lupus erythematosus 32 | 1,056
dermatomyositis 32 | 933
Multiple myeloma 31 | 1,327
astrocytic glioma 31 | 2,241
primary Sjogren syndrome 31 | 789
Anemia 30 | 252
acute quadriplegic myopathy 30 | 1,157
sonic hedgehog group medulloblastoma 30 | 1,482
Hepatitis B 29 | 103
Prostatic Neoplasms 29 | 471
Waldenstrons macroglobulinemia 29 | 765
Leprosy 27 | 77
medulloblastoma 27 | 1,524
primary pancreatic ductal adenocarcinoma 27 | 1,271
Lung Neoplasms 25 | 171
Primary immunodeficiency disease 25 | 52
Skin disease 25 | 65
acute myeloid leukemia 25 | 780
nasopharyngeal carcinoma 24 | 1,056
Asthma 23 | 349
Endometriosis 23 | 535
Hemochromatosis 23 | 55
gastric carcinoma 23 | 832
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,795
Liver carcinoma 22 | 217
Schizophrenia 22 | 501
Vascular disease 22 | 281
Colorectal Neoplasms 21 | 217
Duchenne muscular dystrophy 21 | 602
Pick disease 21 | 1,893
active Crohn's disease 21 | 918
non primary Sjogren syndrome sicca 20 | 840
Adenoma 19 | 165
Obesity 19 | 616
Peripheral Neuropathy 19 | 303
Stomach Neoplasms 19 | 282
Alzheimer's disease 18 | 644
Colonic Neoplasms 18 | 126
IGA Glomerulonephritis 18 | 454
atypical teratoid/rhabdoid tumor 18 | 1,095
Atopic dermatitis 17 | 944
Inflammatory bowel disease 17 | 142

Tissue

Endocrine System 267 | 18,512
Digestive Tract 266 | 18,473
Female tissues 266 | 18,647
Nervous System 266 | 18,561
Urinary Tract 266 | 18,444
Blood and immune system 265 | 17,995
Male tissues 265 | 17,969
Respiratory system 265 | 17,484
Liver and Pancreas 264 | 18,136
Cardiovascular System 263 | 17,958
Skin and soft tissues 253 | 18,115

Target Family

Non-IDG 196 | 11,971
Enzyme 47 | 4,146
Transcription Factor 43 | 1,400
Kinase 33 | 634
GPCR 10 | 406
Epigenetic 5 | 242
Transporter 5 | 473

KEGG Pathway

HTLV-I infection 339 | 339
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
HLA class II histocompatibility antigen, DRB1-14 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 337
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
HLA class I histocompatibility antigen, Cw-5 alpha chain HLA-C Tbio Non-IDG 777.4 0
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.38153 220.3 0
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612