Development Level

Tbio 14 | 10,625
Tchem 5 | 1,890

IMPC Term

abnormal bone structure 3 | 131
decreased total body fat amoun... 3 | 186
increased bone mineral content 3 | 92
decreased circulating serum al... 2 | 79
hypoactivity 2 | 89
increased bone mineral density 2 | 52
increased circulating potassiu... 2 | 31
increased lean body mass 2 | 107
abnormal behavior 1 | 226
abnormal coat appearance 1 | 25
abnormal lung morphology 1 | 15
decreased circulating glucose ... 1 | 121
decreased erythrocyte cell num... 1 | 43
enlarged lymph nodes 1 | 27
enlarged urinary bladder 1 | 4
increased blood urea nitrogen ... 1 | 44
increased circulating alkaline... 1 | 119
short tibia 1 | 82
thrombocytosis 1 | 23

Disease

Mucopolysaccharidosis 15 | 24
ovarian cancer 10 | 8,484
glioblastoma 7 | 5,572
psoriasis 7 | 6,685
subependymal giant cell astrocytoma 7 | 2,287
astrocytoma 6 | 1,493
Cancer 5 | 2,346
Multiple myeloma 5 | 1,327
osteosarcoma 5 | 7,933
Gangliosidosis 4 | 17
Metachromatic leukodystrophy 4 | 13
Mucopolysaccharidosis III 4 | 6
atypical teratoid / rhabdoid tumor 4 | 4,369
diabetes mellitus 4 | 1,663
lung cancer 4 | 4,466
malignant mesothelioma 4 | 3,162
medulloblastoma, large-cell 4 | 6,234
pediatric high grade glioma 4 | 2,712
IGA Glomerulonephritis 3 | 454
Kluver-Bucy syndrome 3 | 6
Neurodegenerative disease 3 | 383
dermatomyositis 3 | 933
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
juvenile dermatomyositis 3 | 1,189
pilocytic astrocytoma 3 | 3,086
tuberculosis 3 | 1,557
Breast cancer 2 | 3,094
Duchenne muscular dystrophy 2 | 602
Fucosidosis 2 | 10
Intellectual disability 2 | 573
Krabbe disease 2 | 11
Mucopolysaccharidosis I 2 | 6
Mucopolysaccharidosis IV 2 | 5
Mucosulfatidosis 2 | 5
Niemann-Pick disease 2 | 11
Sandhoff disease 2 | 3
Urofacial syndrome 2 | 7
active Crohn's disease 2 | 918
adrenocortical carcinoma 2 | 1,427
cutaneous lupus erythematosus 2 | 1,056
ependymoma 2 | 2,514
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 2,254
inclusion-cell disease 2 | 15
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,713
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung cancer 2 | 2,798
Acute kidney injury 1 | 65
Bone Diseases, Developmental 1 | 25
Brain disease 1 | 83
Charcot-Marie-Tooth disease 1 | 74
Corneal Opacity 1 | 3
Diabetes Mellitus, Insulin-Dependent 1 | 76
Endometriosis of uterus 1 | 3
Gaucher disease type 1 1 | 171
Gaucher's disease 1 | 24
Glomerulonephritis 1 | 36
Glycoproteinosis 1 | 13
Goldenhar syndrome 1 | 19
Hydrops Fetalis, Non-Immune 1 | 12
Infertility 1 | 163
Inflammation 1 | 109
Laryngotracheitis 1 | 10
Leiomyoma 1 | 25
Leukodystrophy 1 | 30
Liver Cirrhosis, Experimental 1 | 108
Liver cancer 1 | 31
MPS III B 1 | 1
Mammary Neoplasms 1 | 410
Melanoma 1 | 261
Mucopolysaccharidosis VI 1 | 6
Muscular atrophy 1 | 67
Myoma 1 | 12
Neoplasm Invasiveness 1 | 127
Neoplasm Metastasis 1 | 138
Nephrosis 1 | 18
Nephrotic Syndrome 1 | 48
Neurogenic bladder 1 | 16
Neuronal ceroid lipofuscinosis 1 | 28
Neuropathy 1 | 210
Ochoa syndrome 1 | 2
Osteochondrodysplasias 1 | 15
Osteoporosis 1 | 257
Oxyphilic adenoma 1 | 21
Periodontal disease 1 | 37
Proteinuria 1 | 63
Retinitis pigmentosa 1 | 153
Sly syndrome 1 | 4
Spinal cord disease 1 | 22
Spondyloepiphyseal dysplasia with congenital joint dislocations 1 | 12
Tay-Sachs Disease 1 | 3
Thrombocytopenia 1 | 105
Type 1 diabetes mellitus 1 | 101
Uterine fibroid 1 | 29
nervous system disorder 1 | 53
non-inflammatory breast cancer 1 | 208
pseudo-Hurler polydystrophy 1 | 6

Tissue

Cardiovascular System 19 | 17,958
Digestive Tract 19 | 18,473
Endocrine System 19 | 18,512
Female tissues 19 | 18,647
Liver and Pancreas 19 | 18,136
Male tissues 19 | 17,969
Nervous System 19 | 18,561
Respiratory system 19 | 17,484
Skin and soft tissues 19 | 18,115
Urinary Tract 19 | 18,444
Blood and immune system 18 | 17,995

Target Family

Enzyme 19 | 4,146

KEGG Pathway

Glycosaminoglycan degradation 19 | 19
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hyaluronidase-3 HYAL3 Tbio Enzyme -0.90097 7.70 99
N-acetylgalactosamine-6-sulfatase GALNS Tbio Enzyme -2.40411 261.5 203
N-acetylglucosamine-6-sulfatase GNS Tbio Enzyme -2.61169 423.5 144
Hyaluronidase PH-20 SPAM1 Tbio Enzyme -2.18446 166.4 134
Arylsulfatase B ARSB Tbio Enzyme -2.42590 280.1 198
N-sulphoglucosamine sulphohydrolase SGSH Tbio Enzyme -2.13421 143.4 138
Inactive heparanase-2 HPSE2 Tbio Enzyme -2.44770 286.8 122
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.86069 78.6 191
Hyaluronidase-2 HYAL2 Tbio Enzyme -1.99434 102.5 193
Alpha-N-acetylglucosaminidase NAGLU Tbio Enzyme -2.14685 152.0 61