Development Level

Tbio 19 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal eye morphology 2 | 68
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
absent startle reflex 1 | 24
decreased body length 1 | 101
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
thick skin 1 | 4

Disease

Carcinoma 14 | 11,493
ovarian cancer 12 | 8,520
glioblastoma 11 | 5,792
atypical teratoid / rhabdoid tumor 9 | 5,112
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 8 | 7,950
ependymoma 7 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pituitary cancer 6 | 1,972
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
Radioulnar synostosis 5 | 35
group 3 medulloblastoma 5 | 4,104
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
ulcerative colitis 5 | 1,819
Congenital clubfoot 4 | 109
Desbuquois dysplasia 4 | 13
Ehlers-Danlos syndrome 4 | 43
active Crohn's disease 4 | 922
cystic fibrosis 4 | 1,696
gastric carcinoma 4 | 807
interstitial cystitis 4 | 2,312
Acquired flat foot 3 | 72
Amblyopia 3 | 38
Brachycephaly 3 | 88
Broad cranium shape 3 | 88
Chronic Lymphocytic Leukemia 3 | 262
Craniofacial Abnormalities 3 | 151
Cutis Laxa 3 | 39
Decreased size of teeth 3 | 62
Decreased width of tooth 3 | 59
Downward slant of palpebral fissure 3 | 158
Flatfoot 3 | 73
Foramen Ovale, Patent 3 | 10
Frontal bossing 3 | 157
Generalized elastolysis 3 | 24
Generalized osteopenia 3 | 99
Hanging skin 3 | 24
Hyperopia 3 | 70
Joint laxity 3 | 54
MULTIPLE JOINT DISLOCATIONS, SHORT STATURE, CRANIOFACIAL DYSMORPHISM, AND CONGENITAL HEART DEFECTS 3 | 3
Microdontia (disorder) 3 | 59
Microstomia 3 | 78
Narrow thorax 3 | 53
Osteopenia 3 | 99
Short stature 3 | 531
Small face 3 | 10
Wide skull shape 3 | 88
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Advanced bone age 2 | 35
Arachnodactyly 2 | 49
Brachydactyly 2 | 156
Bulging forehead 2 | 66
Byzanthine arch palate 2 | 194
Cardiomegaly 2 | 116
Clubfoot 2 | 39
Concave bridge of nose 2 | 195
Congenital small ears 2 | 48
Curvature of spine 2 | 282
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
EHLERS-DANLOS SYNDROME, MUSCULOCONTRACTURAL TYPE 1 2 | 2
Eastern equine encephalitis 2 | 16
Ehlers-Danlos syndrome, musculocontractural type 2 | 2
Esotropia 2 | 31
Globe of eye large 2 | 20
Gross motor development delay 2 | 21
Hydrophthalmos 2 | 19
Left Ventricular Hypertrophy 2 | 47
Liver Cirrhosis, Experimental 2 | 769
Low posterior hairline 2 | 52
Osteoarthritis 2 | 184
Prominent forehead 2 | 66
Pseudoxanthoma elasticum 2 | 18
Pulmonary Stenosis 2 | 45
Short metacarpal 2 | 43
Telecanthus 2 | 62
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678
Cardiovascular System 19 | 15,192

Target Family

Enzyme 20 | 4,145

KEGG Pathway

Glycosaminoglycan biosynthesis... 20 | 20
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dermatan-sulfate epimerase DSE Tbio Enzyme -2.57112 360.0 44
Xylosyltransferase 1 XYLT1 Tbio Enzyme -2.10436 129.4 88
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
Carbohydrate sulfotransferase 11 CHST11 Tbio Enzyme -1.44765 27.4 112
Chondroitin sulfate synthase 2 CHPF Tbio Enzyme -1.31542 17.3 129
Carbohydrate sulfotransferase 3 CHST3 Tbio Enzyme -2.32897 204.3 128
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
Xylosyltransferase 2 XYLT2 Tbio Enzyme -2.61071 412.3 78
Chondroitin sulfate glucuronyltransferase CHPF2 Tbio Enzyme -0.51521 3.67 74
Carbohydrate sulfotransferase 7 CHST7 Tbio Enzyme -0.48328 2.73 33