Development Level

Tbio 34 | 10,625
Tchem 4 | 1,890
Tclin 2 | 602

IMPC Term

abnormal behavior 3 | 226
hypoactivity 3 | 89
decreased circulating HDL chol... 2 | 77
preweaning lethality, complete... 2 | 633
thrombocytopenia 2 | 46
abnormal bone structure 1 | 131
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal retina morphology 1 | 100
abnormal skin appearance 1 | 8
anophthalmia 1 | 20
craniofacial phenotype 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating thyroxin... 1 | 5
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased circulating unsatura... 1 | 1
decreased food intake 1 | 6
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased mean platelet volume 1 | 12
decreased red blood cell distr... 1 | 11
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
female infertility 1 | 34
herniated abdominal wall 1 | 4
hydrops fetalis 1 | 22
increased body weight 1 | 42
increased circulating bilirubi... 1 | 16
increased heart rate variabili... 1 | 4
increased lean body mass 1 | 107
increased rib number 1 | 41
male infertility 1 | 62
microphthalmia 1 | 15
pale yolk sac 1 | 12
prenatal lethality prior to he... 1 | 64
small adrenal glands 1 | 15

Disease

psoriasis 19 | 6,685
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
osteosarcoma 16 | 7,933
ovarian cancer 14 | 8,484
pancreatic cancer 12 | 2,300
lung cancer 11 | 4,466
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
medulloblastoma, large-cell 9 | 6,234
non-small cell lung cancer 9 | 2,798
posterior fossa group B ependymoma 9 | 1,530
atypical teratoid / rhabdoid tumor 8 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
lung adenocarcinoma 8 | 2,713
malignant mesothelioma 8 | 3,162
pituitary cancer 8 | 1,972
glioblastoma 7 | 5,572
group 3 medulloblastoma 7 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
Breast cancer 6 | 3,094
Cancer 6 | 2,346
adrenocortical carcinoma 6 | 1,427
breast carcinoma 6 | 1,614
colon cancer 6 | 1,475
invasive ductal carcinoma 6 | 2,950
Hyperhomocysteinemia 5 | 34
Schizophrenia 5 | 501
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,875
interstitial cystitis 5 | 2,299
nephrosclerosis 5 | 329
oligodendroglioma 5 | 2,849
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
primary pancreatic ductal adenocarcinoma 5 | 1,271
Dementia 4 | 129
Down syndrome 4 | 548
Homocystinuria 4 | 23
Hypermethioninemia 4 | 12
Multiple myeloma 4 | 1,327
Prostatic Neoplasms 4 | 471
adult high grade glioma 4 | 2,148
aldosterone-producing adenoma 4 | 664
atypical teratoid/rhabdoid tumor 4 | 1,095
cystic fibrosis 4 | 1,665
inflammatory breast cancer 4 | 404
lung carcinoma 4 | 2,844
nasopharyngeal carcinoma 4 | 1,056
non primary Sjogren syndrome sicca 4 | 840
non-small cell lung carcinoma 4 | 413
sonic hedgehog group medulloblastoma 4 | 1,482
subependymal giant cell astrocytoma 4 | 2,287
Aphasia 3 | 22
Atherosclerosis 3 | 275
Autistic Disorder 3 | 320
Depressive disorder 3 | 48
Diabetes Mellitus, Non-Insulin-Dependent 3 | 157
Glycine encephalopathy 3 | 28
Intellectual disability 3 | 573
Lymphoma, Non-Hodgkin 3 | 22
Nonketotic Hyperglycinemia 3 | 3
Primary hyperoxaluria 3 | 15
Serine deficiency 3 | 9
acute myeloid leukemia 3 | 780
dermatomyositis 3 | 933
diabetes mellitus 3 | 1,663
fibroadenoma 3 | 557
gastric carcinoma 3 | 832
pancreatic carcinoma 3 | 567
spina bifida 3 | 1,064
tuberculosis 3 | 1,557
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Atopic dermatitis 2 | 944
Bipolar Disorder 2 | 266
Endometriosis 2 | 535
Epilepsy 2 | 346
Huntington Disease 2 | 12
Hypertension 2 | 287
Hypertensive disease 2 | 193
Kidney disease 2 | 396
Major Depressive Disorder 2 | 106
Mammary Neoplasms 2 | 410
Microcephaly 2 | 149
Neurodegenerative disease 2 | 383
Parkinson Disease 2 | 102
Parkinson's disease 2 | 364
Polycystic Ovary Syndrome 2 | 332
Prostate cancer 2 | 172
Stomach Neoplasms 2 | 282
Tinea corporis 2 | 25
Toxic encephalopathy 2 | 131
Vascular disease 2 | 281
X-linked cerebral adrenoleukodystrophy 2 | 115
acute quadriplegic myopathy 2 | 1,157
astrocytoma 2 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic rhinosinusitis 2 | 512
hepatocellular carcinoma 2 | 532
mucosa-associated lymphoid tissue lymphoma 2 | 480
progressive supranuclear palsy 2 | 674

Tissue

Blood and immune system 40 | 17,995
Cardiovascular System 40 | 17,958
Digestive Tract 40 | 18,473
Female tissues 40 | 18,647
Liver and Pancreas 40 | 18,136
Male tissues 40 | 17,969
Nervous System 40 | 18,561
Endocrine System 39 | 18,512
Skin and soft tissues 39 | 18,115
Urinary Tract 39 | 18,444
Respiratory system 38 | 17,484

Target Family

Enzyme 37 | 4,146
Non-IDG 2 | 11,971
Kinase 1 | 634

KEGG Pathway

Glycine, serine and threonine ... 40 | 40
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.31313 210.4 193
Choline dehydrogenase, mitochondrial CHDH Tbio Enzyme -1.38953 24.8 68
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.11277 1238.0 122
Glycine dehydrogenase (decarboxylating), mitochondrial GLDC Tbio Enzyme -1.68278 53.7 117
Retina-specific copper amine oxidase AOC2 Tchem Enzyme -2.24632 179.3 53
Cystathionine beta-synthase-like protein CBS Tbio Non-IDG -3.45921 2982.0 0
Glycerate kinase GLYCTK Tbio Kinase -1.27397 19.4 162
D-3-phosphoglycerate dehydrogenase PHGDH Tbio Enzyme -3.12793 1317.4 261
Phosphoserine aminotransferase PSAT1 Tbio Enzyme -2.22389 167.4 113
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.37979 2431.7 224