Development Level

Tbio 51 | 10,625
Tchem 27 | 1,890
Tdark 15 | 7,003
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal lens morphology 2 | 73
decreased bone mineral content 2 | 157
decreased circulating glucose ... 2 | 121
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
increased red blood cell distr... 2 | 21
preweaning lethality, incomple... 2 | 260
abnormal QRS complex 1 | 25
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
decreased NK T cell number 1 | 28
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating lactate ... 1 | 1
decreased eosinophil cell numb... 1 | 41
decreased lactate dehydrogenas... 1 | 14
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
hydrometra 1 | 13
increased B cell number 1 | 23
increased body weight 1 | 42
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased heart rate variabili... 1 | 4
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased mean platelet volume 1 | 19
increased monocyte cell number 1 | 27
increased prepulse inhibition 1 | 21
increased total body fat amoun... 1 | 57
male infertility 1 | 62
oligodactyly 1 | 14
small seminal vesicle 1 | 6
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

osteosarcoma 51 | 7,933
ovarian cancer 42 | 8,484
psoriasis 37 | 6,685
medulloblastoma, large-cell 35 | 6,234
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,289
invasive ductal carcinoma 24 | 2,950
atypical teratoid / rhabdoid tumor 23 | 4,369
glioblastoma 23 | 5,572
lung cancer 22 | 4,466
non-small cell lung cancer 22 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
group 4 medulloblastoma 18 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
lung carcinoma 18 | 2,844
ulcerative colitis 18 | 2,087
Breast cancer 17 | 3,094
Pick disease 17 | 1,893
malignant mesothelioma 16 | 3,162
pilocytic astrocytoma 16 | 3,086
oligodendroglioma 15 | 2,849
primitive neuroectodermal tumor 15 | 3,031
ductal carcinoma in situ 14 | 1,745
ependymoma 14 | 2,514
lung adenocarcinoma 14 | 2,713
pancreatic cancer 14 | 2,300
adult high grade glioma 13 | 2,148
active Crohn's disease 12 | 918
breast carcinoma 12 | 1,614
pediatric high grade glioma 12 | 2,712
subependymal giant cell astrocytoma 12 | 2,287
astrocytic glioma 11 | 2,241
interstitial cystitis 11 | 2,299
sonic hedgehog group medulloblastoma 11 | 1,482
group 3 medulloblastoma 10 | 2,254
pituitary cancer 10 | 1,972
posterior fossa group B ependymoma 10 | 1,530
Rheumatoid Arthritis 9 | 1,160
esophageal adenocarcinoma 9 | 737
tuberculosis 9 | 1,557
Sengers syndrome 7 | 17
Toxic encephalopathy 7 | 131
diabetes mellitus 7 | 1,663
primary pancreatic ductal adenocarcinoma 7 | 1,271
spina bifida 7 | 1,064
Multiple myeloma 6 | 1,327
acute quadriplegic myopathy 6 | 1,157
adrenocortical carcinoma 6 | 1,427
colon cancer 6 | 1,475
gastric carcinoma 6 | 832
non primary Sjogren syndrome sicca 6 | 840
Atopic dermatitis 5 | 944
Coronary artery disease 5 | 240
Down syndrome 5 | 548
Lipodystrophy 5 | 32
cystic fibrosis 5 | 1,665
dermatomyositis 5 | 933
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
Alzheimer's disease 4 | 644
Amyotrophic Lateral Sclerosis 4 | 431
Atherosclerosis 4 | 275
Barth syndrome 4 | 23
Cancer 4 | 2,346
Carcinoma 4 | 2,147
Newborn respiratory distress syndrome 4 | 8
Parkinson's disease 4 | 364
Waldenstrons macroglobulinemia 4 | 765
astrocytoma 4 | 1,493
juvenile dermatomyositis 4 | 1,189
nephrosclerosis 4 | 329
posterior fossa group A ependymoma 4 | 1,511
progressive supranuclear palsy 4 | 674
Amnestic disorder 3 | 37
Arthritis 3 | 248
Duchenne muscular dystrophy 3 | 602
IGA Glomerulonephritis 3 | 454
Ileocolitis 3 | 6
Intellectual disability 3 | 573
Lipid metabolism disorder 3 | 102
Schizophrenia 3 | 501
aldosterone-producing adenoma 3 | 664
atypical teratoid/rhabdoid tumor 3 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
fibroadenoma 3 | 557
glioblastoma multiforme 3 | 347
hereditary spastic paraplegia 3 | 313
inflammatory breast cancer 3 | 404
pancreatic carcinoma 3 | 567
Becker muscular dystrophy 2 | 187
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Juvenile arthritis 2 | 124
Neurodegenerative disease 2 | 383
Reperfusion Injury 2 | 84
Seizures 2 | 95
hepatocellular carcinoma 2 | 532
mucosa-associated lymphoid tissue lymphoma 2 | 480
non diabetic and post-ischemic heart failure 2 | 200
tuberculosis and treatment for 3 months 2 | 327

Tissue

Nervous System 94 | 18,561
Cardiovascular System 93 | 17,958
Digestive Tract 93 | 18,473
Endocrine System 93 | 18,512
Female tissues 93 | 18,647
Skin and soft tissues 93 | 18,115
Urinary Tract 93 | 18,444
Blood and immune system 92 | 17,995
Liver and Pancreas 92 | 18,136
Male tissues 90 | 17,969
Respiratory system 90 | 17,484

Target Family

Enzyme 85 | 4,146
Kinase 7 | 634
Non-IDG 2 | 11,971

KEGG Pathway

Glycerophospholipid metabolism 94 | 94
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial PGS1 Tdark Enzyme -0.35218 2.20 100
Phosphatidylserine synthase 2 PTDSS2 Tbio Enzyme -0.74689 6.34 68
Group 10 secretory phospholipase A2 PLA2G10 Tchem Enzyme -2.39398 288.4 31
Lysophospholipid acyltransferase 2 MBOAT2 Tbio Enzyme -1.34198 18.9 57
Phosphatidylserine synthase 1 PTDSS1 Tbio Enzyme -1.84361 76.0 90
Diacylglycerol kinase gamma DGKG Tbio Enzyme -1.22622 18.8 58
Glycerol-3-phosphate acyltransferase 2, mitochondrial GPAT2 Tdark Enzyme -0.79239 6.58 36
Choline-phosphate cytidylyltransferase A PCYT1A Tbio Enzyme -2.35478 227.3 176
Diacylglycerol kinase beta DGKB Tbio Enzyme -1.49580 35.3 115
Group 3 secretory phospholipase A2 PLA2G3 Tchem Enzyme -0.81753 7.31 117