Development Level

Tbio 36 | 10,625
Tchem 13 | 1,890
Tclin 6 | 602
Tdark 4 | 7,003

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

decreased bone mineral content 2 | 157
decreased mean corpuscular vol... 2 | 50
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal response to tactile s... 1 | 16
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
hydrometra 1 | 13
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart rate variabili... 1 | 4
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased monocyte cell number 1 | 27
increased red blood cell distr... 1 | 21
increased total body fat amoun... 1 | 57
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
thrombocytosis 1 | 23

Disease

psoriasis 28 | 6,685
osteosarcoma 25 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
medulloblastoma, large-cell 21 | 6,234
ovarian cancer 20 | 8,484
glioblastoma 17 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
malignant mesothelioma 15 | 3,162
lung cancer 14 | 4,466
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
invasive ductal carcinoma 13 | 2,950
ductal carcinoma in situ 12 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Breast cancer 11 | 3,094
atypical teratoid / rhabdoid tumor 11 | 4,369
diabetes mellitus 11 | 1,663
ulcerative colitis 11 | 2,087
non-small cell lung cancer 10 | 2,798
Atopic dermatitis 9 | 944
Obesity 9 | 616
breast carcinoma 9 | 1,614
lung carcinoma 9 | 2,844
pancreatic cancer 9 | 2,300
primitive neuroectodermal tumor 9 | 3,031
Pick disease 8 | 1,893
active Crohn's disease 8 | 918
pediatric high grade glioma 8 | 2,712
pilocytic astrocytoma 8 | 3,086
group 4 medulloblastoma 7 | 1,875
pituitary cancer 7 | 1,972
tuberculosis 7 | 1,557
adult high grade glioma 6 | 2,148
colon cancer 6 | 1,475
cystic fibrosis 6 | 1,665
interstitial cystitis 6 | 2,299
primary pancreatic ductal adenocarcinoma 6 | 1,271
subependymal giant cell astrocytoma 6 | 2,287
Cancer 5 | 2,346
Coronary artery disease 5 | 240
Fatty liver disease 5 | 84
Lipid metabolism disorder 5 | 102
Rheumatoid Arthritis 5 | 1,160
Succinic semialdehyde dehydrogenase deficiency 5 | 16
acute quadriplegic myopathy 5 | 1,157
astrocytic glioma 5 | 2,241
astrocytoma 5 | 1,493
esophageal adenocarcinoma 5 | 737
fibroadenoma 5 | 557
lung adenocarcinoma 5 | 2,713
oligodendroglioma 5 | 2,849
posterior fossa group B ependymoma 5 | 1,530
sonic hedgehog group medulloblastoma 5 | 1,482
Atherosclerosis 4 | 275
Lipodystrophy 4 | 32
Metabolic syndrome X 4 | 155
Neutral lipid storage disease 4 | 14
Sengers syndrome 4 | 17
cutaneous lupus erythematosus 4 | 1,056
dermatomyositis 4 | 933
ependymoma 4 | 2,514
group 3 medulloblastoma 4 | 2,254
medulloblastoma 4 | 1,524
nasopharyngeal carcinoma 4 | 1,056
Cardiovascular system disease 3 | 194
Chronic Lymphocytic Leukemia 3 | 242
Coronary heart disease 3 | 59
Diabetic complication 3 | 3
Kidney disease 3 | 396
Pancreatitis 3 | 97
Vascular disease 3 | 281
acute myeloid leukemia 3 | 780
adrenocortical carcinoma 3 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group A ependymoma 3 | 1,511
Barth syndrome 2 | 23
Becker muscular dystrophy 2 | 187
Carcinoma 2 | 2,147
Cardiomyopathy 2 | 110
Cataract 2 | 104
Colonic Neoplasms 2 | 126
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Disease Progression 2 | 125
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Hypertension 2 | 287
Osteoporosis 2 | 257
Steatorrhea 2 | 20
Stomach Neoplasms 2 | 282
Type 2 diabetes mellitus 2 | 189
aldosterone-producing adenoma 2 | 664
chronic lymphosyte leukemia 2 | 232
gastric carcinoma 2 | 832
juvenile dermatomyositis 2 | 1,189
limb girdle muscular dystrophy 2B 2 | 74
mucosa-associated lymphoid tissue lymphoma 2 | 480
nephrosclerosis 2 | 329
non diabetic and post-ischemic heart failure 2 | 200
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686

Tissue

Liver and Pancreas 59 | 18,136
Nervous System 59 | 18,561
Blood and immune system 58 | 17,995
Digestive Tract 58 | 18,473
Cardiovascular System 57 | 17,958
Endocrine System 57 | 18,512
Female tissues 57 | 18,647
Male tissues 57 | 17,969
Skin and soft tissues 57 | 18,115
Urinary Tract 57 | 18,444
Respiratory system 56 | 17,484

Target Family

Enzyme 53 | 4,146
Kinase 6 | 634

KEGG Pathway

Glycerolipid metabolism 59 | 59
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.11277 1238.0 122
Lysophospholipid acyltransferase 2 MBOAT2 Tbio Enzyme -1.34198 18.9 57
Diacylglycerol kinase gamma DGKG Tbio Enzyme -1.22622 18.8 58
Glycerol-3-phosphate acyltransferase 2, mitochondrial GPAT2 Tdark Enzyme -0.79239 6.58 36
Acylglycerol kinase, mitochondrial AGK Tbio Enzyme -1.82132 67.8 115
Diacylglycerol kinase beta DGKB Tbio Enzyme -1.49580 35.3 115
Diacylglycerol kinase eta DGKH Tbio Kinase -1.39310 28.9 73
Glycerate kinase GLYCTK Tbio Kinase -1.27397 19.4 162
Alcohol dehydrogenase [NADP(+)] AKR1A1 Tchem Enzyme -2.11529 128.8 337
Diacylglycerol kinase theta DGKQ Tbio Kinase -1.55970 34.2 153