Development Level

Tbio 41 | 11,651
Tchem 11 | 1,388
Tclin 6 | 612
Tdark 3 | 6,593

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased bone mineral content 2 | 151
decreased mean corpuscular vol... 2 | 79
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hypoactivity 1 | 132
increased heart rate variabili... 1 | 7
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 43 | 11,493
psoriasis 28 | 6,694
osteosarcoma 25 | 7,950
ovarian cancer 22 | 8,520
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
medulloblastoma, large-cell 21 | 6,241
glioblastoma 18 | 5,792
lung cancer 18 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 15 | 2,951
malignant mesothelioma 15 | 3,232
ductal carcinoma in situ 14 | 1,745
Breast cancer 13 | 3,578
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
adult high grade glioma 12 | 3,801
atypical teratoid / rhabdoid tumor 12 | 5,112
Obesity 11 | 678
diabetes mellitus 11 | 1,728
non-small cell lung cancer 11 | 2,890
pancreatic cancer 11 | 2,398
breast carcinoma 10 | 1,638
primitive neuroectodermal tumor 10 | 3,035
Astrocytoma, Pilocytic 9 | 3,081
Atopic dermatitis 9 | 952
Autosomal recessive predisposition 9 | 1,442
lung carcinoma 9 | 2,843
tuberculosis 9 | 2,010
Liver Cirrhosis, Experimental 8 | 769
Pick disease 8 | 1,894
active Crohn's disease 8 | 922
cystic fibrosis 7 | 1,696
ependymoma 7 | 4,679
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
Lipid metabolism disorder 6 | 114
active ulcerative colitis 6 | 764
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 1,819
Cancer 5 | 2,499
Coronary artery disease 5 | 268
Fatty liver disease 5 | 103
Kidney cancer 5 | 2,613
Lipodystrophy 5 | 40
Rheumatoid arthritis 5 | 1,191
Succinic semialdehyde dehydrogenase deficiency 5 | 16
acute quadriplegic myopathy 5 | 1,158
esophageal adenocarcinoma 5 | 737
fibroadenoma 5 | 559
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
posterior fossa group B ependymoma 5 | 416
Atherosclerosis 4 | 291
Cardiovascular system disease 4 | 246
Dull intelligence 4 | 645
Epilepsy 4 | 792
Hepatomegaly 4 | 285
Hyperlipidemia 4 | 43
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Osteoporosis 4 | 363
Poor school performance 4 | 645
Sengers syndrome 4 | 18
Type 2 diabetes mellitus 4 | 272
astrocytoma 4 | 1,146
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
nasopharyngeal carcinoma 4 | 1,058
Alcoholic Intoxication, Chronic 3 | 289
Bipolar Disorder 3 | 666
Cardiomyopathy 3 | 116
Cataract 3 | 297
Cholestasis 3 | 155
Chronic Lymphocytic Leukemia 3 | 262
Diabetic complication 3 | 3
Hypertriglyceridemia result 3 | 37
Kidney disease 3 | 430
Melanoma 3 | 711
Myalgia 3 | 54
Myocardial Infarction 3 | 151
Pancreatitis 3 | 123
Schizophrenia 3 | 1,160
Seizures 3 | 596
Short stature 3 | 531
Splenomegaly 3 | 190
Vascular disease 3 | 319
Vomiting 3 | 116
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
gastric carcinoma 3 | 807
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064

Tissue

Endocrine System 59 | 18,159
Digestive Tract 58 | 17,369
Female tissues 58 | 17,400
Male tissues 57 | 17,142
Skin and soft tissues 57 | 17,230
Liver and Pancreas 56 | 16,750
Nervous System 56 | 16,725
Urinary Tract 56 | 16,678
Respiratory system 55 | 16,393
Blood and immune system 54 | 16,909
Cardiovascular System 54 | 15,192

Target Family

Enzyme 55 | 4,145
Kinase 6 | 634

KEGG Pathway

Glycerolipid metabolism 61 | 61
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelial lipase LIPG Tchem Enzyme -2.28530 192.2 712
Aldehyde dehydrogenase X, mitochondrial ALDH1B1 Tbio Enzyme -1.73034 52.5 194
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha AGPAT1 Tbio Enzyme -1.04175 10.1 88
Aldose reductase AKR1B1 Tclin Enzyme -3.27314 1915.8 350
Diacylglycerol kinase zeta DGKZ Tbio Enzyme -1.89662 90.6 157
Monoglyceride lipase MGLL Tchem Enzyme -2.48367 314.7 296
Glycerol-3-phosphate acyltransferase 4 GPAT4 Tbio Enzyme -1.61972 41.3 205
Glycerol-3-phosphate acyltransferase 2, mitochondrial GPAT2 Tbio Enzyme -0.97159 8.93 38
1-acyl-sn-glycerol-3-phosphate acyltransferase beta AGPAT2 Tchem Enzyme -1.95996 90.8 127
Acylglycerol kinase, mitochondrial AGK Tbio Enzyme -1.87891 75.3 137