Development Level

Tbio 31 | 11,445
Tchem 14 | 1,598
Tclin 5 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 3 | 239
abnormal heart morphology 2 | 162
decreased body length 2 | 101
decreased lean body mass 2 | 135
increased monocyte cell number 2 | 63
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent optic nerve 1 | 2
absent testes 1 | 6
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased heart rate 1 | 18
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
long tibia 1 | 25
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
small testis 1 | 58

Disease

ovarian cancer 26 | 8,520
Carcinoma 25 | 11,493
psoriasis 25 | 6,694
Cancer 23 | 2,499
glioblastoma 21 | 5,792
lung cancer 20 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
medulloblastoma, large-cell 16 | 6,241
osteosarcoma 16 | 7,950
atypical teratoid / rhabdoid tumor 15 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
non-small cell lung cancer 14 | 2,890
tuberculosis 14 | 2,010
Breast cancer 13 | 3,578
invasive ductal carcinoma 13 | 2,951
lung carcinoma 13 | 2,843
Schizophrenia 12 | 1,160
group 3 medulloblastoma 12 | 4,104
lung adenocarcinoma 12 | 2,716
Multiple myeloma 11 | 1,332
colon cancer 11 | 1,478
diabetes mellitus 11 | 1,728
interstitial cystitis 11 | 2,312
primitive neuroectodermal tumor 11 | 3,035
subependymal giant cell astrocytoma 11 | 2,287
ductal carcinoma in situ 10 | 1,745
ependymoma 10 | 4,679
malignant mesothelioma 10 | 3,232
pancreatic cancer 10 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Prostatic Neoplasms 9 | 495
adrenocortical carcinoma 9 | 1,428
oligodendroglioma 9 | 2,850
Chemical and Drug Induced Liver Injury 8 | 195
Neurodegenerative Diseases 8 | 38
Neurodegenerative Disorders 8 | 79
cystic fibrosis 8 | 1,696
primary pancreatic ductal adenocarcinoma 8 | 1,109
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
Hypertension 7 | 396
adult high grade glioma 7 | 3,801
breast carcinoma 7 | 1,638
nasopharyngeal carcinoma 7 | 1,058
Autosomal recessive predisposition 6 | 1,442
Carcinoma, Hepatocellular 6 | 228
Epilepsy 6 | 792
Liver Cirrhosis, Experimental 6 | 769
Liver carcinoma 6 | 240
Lung Neoplasms 6 | 232
acute quadriplegic myopathy 6 | 1,158
astrocytic glioma 6 | 2,597
esophageal adenocarcinoma 6 | 737
Bipolar Disorder 5 | 666
Bladder Neoplasm 5 | 112
Colorectal Neoplasms 5 | 243
Contact Dermatitis 5 | 81
Dermatitis, Contact 5 | 71
Endometriosis 5 | 540
Hypertensive disease 5 | 292
Toxic encephalopathy 5 | 141
Urinary Bladder Neoplasms 5 | 114
Vascular disease 5 | 319
Xeroderma pigmentosum group D 5 | 33
active Crohn's disease 5 | 922
cutaneous lupus erythematosus 5 | 1,057
group 4 medulloblastoma 5 | 1,855
juvenile dermatomyositis 5 | 1,187
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
Anemia 4 | 365
Anemia, Hemolytic 4 | 55
Asthma 4 | 385
Breast Neoplasms 4 | 445
Carcinoma, Non-Small-Cell Lung 4 | 107
Depressive disorder 4 | 409
Disease Models, Animal 4 | 155
Keshan disease 4 | 17
Mammary Neoplasms 4 | 425
Muscle hypotonia 4 | 571
Myocardial Ischemia 4 | 169
Non-alcoholic Fatty Liver Disease 4 | 42
Osteoarthritis 4 | 184
Parkinson Disease 4 | 64
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
hepatocellular carcinoma 4 | 547
nephrosclerosis 4 | 333
non-small cell lung carcinoma 4 | 317
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074
Pick disease 3 | 1,894

Tissue

Endocrine System 50 | 18,159
Male tissues 50 | 17,142
Blood and immune system 48 | 16,909
Digestive Tract 48 | 17,369
Female tissues 48 | 17,400
Skin and soft tissues 48 | 17,230
Liver and Pancreas 47 | 16,750
Nervous System 47 | 16,725
Respiratory system 47 | 16,393
Urinary Tract 47 | 16,678
Cardiovascular System 43 | 15,192

Target Family

Enzyme 53 | 4,145
Non-IDG 1 | 12,091

KEGG Pathway

Glutathione metabolism 54 | 54
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
6-phosphogluconate dehydrogenase, decarboxylating PGD Tchem Enzyme -2.56683 355.7 211
N-acetyltransferase 8 NAT8 Tbio Enzyme -1.74418 54.5 143
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Glutathione S-transferase theta-2 GSTT2 Tbio Enzyme -1.25193 16.8 0
Spermine synthase SMS Tchem Enzyme -1.50353 28.6 215
Cytosol aminopeptidase LAP3 Tchem Enzyme -2.59176 385.7 172
Glutathione S-transferase A5 GSTA5 Tdark Enzyme -0.93224 8.65 46
Glutathione synthetase GSS Tbio Enzyme -2.78139 592.8 229
Glutathione reductase, mitochondrial GSR Tclin Enzyme -3.00773 863.8 276
Gamma-glutamylcyclotransferase GGCT Tbio Enzyme -2.20495 142.5 128