Development Level

Tbio 50 | 10,625
Tchem 39 | 1,890
Tclin 18 | 602
Tdark 9 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

abnormal bone mineralization 5 | 55
abnormal bone structure 5 | 131
increased heart weight 5 | 37
preweaning lethality, incomple... 5 | 260
abnormal behavior 4 | 226
decreased lean body mass 3 | 195
hyperactivity 3 | 108
abnormal spleen morphology 2 | 36
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating choleste... 2 | 85
decreased total body fat amoun... 2 | 186
hypoactivity 2 | 89
increased bone mineral content 2 | 92
male infertility 2 | 62
preweaning lethality, complete... 2 | 633
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal vocalization 1 | 21
cataract 1 | 26
decreased CD4-positive, CD25-p... 1 | 24
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating insulin ... 1 | 75
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased neutrophil cell numb... 1 | 37
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged heart 1 | 111
enlarged spleen 1 | 26
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 107
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
small epididymis 1 | 3
small kidney 1 | 10
small superior vagus ganglion 1 | 20
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

medulloblastoma, large-cell 70 | 6,234
glioblastoma 69 | 5,572
atypical teratoid / rhabdoid tumor 56 | 4,369
ovarian cancer 54 | 8,484
psoriasis 53 | 6,685
primitive neuroectodermal tumor 52 | 3,031
pilocytic astrocytoma 51 | 3,086
osteosarcoma 50 | 7,933
oligodendroglioma 46 | 2,849
lung carcinoma 42 | 2,844
Carcinoma 41 | 2,147
Schizophrenia 40 | 501
ependymoma 37 | 2,514
subependymal giant cell astrocytoma 37 | 2,287
pediatric high grade glioma 35 | 2,712
astrocytic glioma 32 | 2,241
Pick disease 30 | 1,893
adult high grade glioma 30 | 2,148
lung cancer 29 | 4,466
Breast cancer 28 | 3,094
Epilepsy 27 | 346
medulloblastoma 27 | 1,524
pituitary cancer 24 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
astrocytoma 22 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,956
invasive ductal carcinoma 22 | 2,950
posterior fossa group A ependymoma 22 | 1,511
malignant mesothelioma 21 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
lung adenocarcinoma 20 | 2,713
non-small cell lung cancer 19 | 2,798
pancreatic cancer 19 | 2,300
group 4 medulloblastoma 18 | 1,875
Autistic Disorder 17 | 320
Parkinson's disease 17 | 364
interstitial cystitis 17 | 2,299
Toxic encephalopathy 16 | 131
group 3 medulloblastoma 16 | 2,254
Intellectual disability 15 | 573
ulcerative colitis 15 | 2,087
Bipolar Disorder 14 | 266
colon cancer 14 | 1,475
Cancer 13 | 2,346
Obesity 13 | 616
Rheumatoid Arthritis 13 | 1,160
breast carcinoma 13 | 1,614
ductal carcinoma in situ 13 | 1,745
Alzheimer's disease 12 | 644
General anesthesia 11 | 53
Lennox-Gastaut syndrome 11 | 34
Local anesthesia 11 | 40
Simple partial seizure 11 | 26
atypical teratoid/rhabdoid tumor 11 | 1,095
cystic fibrosis 11 | 1,665
sonic hedgehog group medulloblastoma 11 | 1,482
Amyotrophic Lateral Sclerosis 10 | 431
Substance Withdrawal Syndrome 10 | 52
adrenocortical carcinoma 10 | 1,427
juvenile dermatomyositis 10 | 1,189
non primary Sjogren syndrome sicca 10 | 840
Alcohol dependence 9 | 107
Cocaine-Related Disorders 9 | 88
Epilepsy characterized by intractable complex partial seizures 9 | 28
Major Depressive Disorder 9 | 106
Migraine Prevention 9 | 22
Tonic-clonic epilepsy 9 | 47
active Crohn's disease 9 | 918
cutaneous lupus erythematosus 9 | 1,056
gastric carcinoma 9 | 832
Neurodegenerative disease 8 | 383
diabetes mellitus 8 | 1,663
posterior fossa group B ependymoma 8 | 1,530
Alcoholism 7 | 14
Arteriosclerotic Parkinsonism 7 | 8
Cardiomegaly 7 | 66
Down syndrome 7 | 548
Duchenne muscular dystrophy 7 | 602
Extrapyramidal disease 7 | 8
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Multiple myeloma 7 | 1,327
Parkinsonism 7 | 19
Postencephalitic parkinsonism 7 | 12
primary Sjogren syndrome 7 | 789
primary pancreatic ductal adenocarcinoma 7 | 1,271
progressive supranuclear palsy 7 | 674
tuberculosis 7 | 1,557
Adenoma 6 | 165
Atopic dermatitis 6 | 944
Attention deficit hyperactivity disorder 6 | 156
Brain Ischemia 6 | 87
Carney complex 6 | 23
Epilepsy, Temporal Lobe 6 | 23
Heart disease 6 | 279
Huntington's disease 6 | 72
Kidney disease 6 | 396
Waldenstrons macroglobulinemia 6 | 765
esophageal adenocarcinoma 6 | 737
sarcoidosis 6 | 358

Tissue

Digestive Tract 115 | 18,473
Endocrine System 115 | 18,512
Female tissues 115 | 18,647
Liver and Pancreas 115 | 18,136
Nervous System 115 | 18,561
Male tissues 114 | 17,969
Urinary Tract 114 | 18,444
Blood and immune system 113 | 17,995
Cardiovascular System 113 | 17,958
Skin and soft tissues 112 | 18,115
Respiratory system 111 | 17,484

Target Family

Non-IDG 36 | 11,971
Enzyme 27 | 4,146
Ion Channel 24 | 341
Transporter 11 | 473
Kinase 10 | 634
GPCR 8 | 406

KEGG Pathway

Glutamatergic synapse 116 | 116
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.97274 103.1 38
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.58202 42.2 123
Excitatory amino acid transporter 4 SLC1A6 Tbio Transporter -1.83815 70.5 92
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.31340 205.5 237
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 GNB2 Tbio Non-IDG -0.43889 2.98 102
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 Tbio Non-IDG -1.15715 18.1 144
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA Tchem Enzyme -2.95943 932.4 290
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.66594 47.2 113
Guanine nucleotide-binding protein G(i) subunit alpha-2 GNAI2 Tbio Non-IDG -1.23038 16.6 188