Development Level

Tchem 27 | 1,890
Tbio 26 | 10,625
Tclin 19 | 602
Tdark 4 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

abnormal bone structure 7 | 131
abnormal bone mineralization 5 | 55
increased heart weight 4 | 37
preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
abnormal spleen morphology 2 | 36
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 195
increased circulating alkaline... 2 | 119
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal response to tactile s... 1 | 16
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
decreased NK T cell number 1 | 28
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased startle reflex 1 | 48
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
male infertility 1 | 62
preweaning lethality, incomple... 1 | 260
small epididymis 1 | 3
tremors 1 | 34

Disease

psoriasis 38 | 6,685
medulloblastoma, large-cell 37 | 6,234
ovarian cancer 37 | 8,484
glioblastoma 35 | 5,572
osteosarcoma 29 | 7,933
pilocytic astrocytoma 26 | 3,086
primitive neuroectodermal tumor 25 | 3,031
atypical teratoid / rhabdoid tumor 24 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
lung cancer 23 | 4,466
pancreatic cancer 23 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,956
Breast cancer 21 | 3,094
Carcinoma 21 | 2,147
oligodendroglioma 21 | 2,849
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,988
lung adenocarcinoma 20 | 2,713
lung carcinoma 19 | 2,844
pediatric high grade glioma 19 | 2,712
adult high grade glioma 18 | 2,148
ependymoma 18 | 2,514
subependymal giant cell astrocytoma 18 | 2,287
Cancer 16 | 2,346
malignant mesothelioma 16 | 3,162
Pick disease 15 | 1,893
astrocytoma 15 | 1,493
group 3 medulloblastoma 15 | 2,254
pituitary cancer 15 | 1,972
astrocytic glioma 14 | 2,241
atypical teratoid/rhabdoid tumor 14 | 1,095
interstitial cystitis 14 | 2,299
invasive ductal carcinoma 14 | 2,950
ulcerative colitis 14 | 2,087
colon cancer 13 | 1,475
diabetes mellitus 11 | 1,663
group 4 medulloblastoma 11 | 1,875
non-small cell lung cancer 11 | 2,798
Atrial Fibrillation 10 | 110
Down syndrome 10 | 548
Obesity 10 | 616
cystic fibrosis 10 | 1,665
medulloblastoma 10 | 1,524
posterior fossa group A ependymoma 10 | 1,511
sonic hedgehog group medulloblastoma 10 | 1,482
Adenoma 9 | 165
Duchenne muscular dystrophy 9 | 602
cutaneous lupus erythematosus 9 | 1,056
posterior fossa group B ependymoma 9 | 1,530
primary pancreatic ductal adenocarcinoma 9 | 1,271
Epilepsy 8 | 346
Kidney disease 8 | 396
Rheumatoid Arthritis 8 | 1,160
Acromegaly 7 | 40
Chronic heart failure 7 | 46
Congestive heart failure 7 | 30
Cushing's syndrome 7 | 47
Multiple Endocrine Neoplasia Type 1 7 | 30
Poisoning by digitalis glycoside 7 | 8
Schizophrenia 7 | 501
breast carcinoma 7 | 1,614
ductal carcinoma in situ 7 | 1,745
gastric carcinoma 7 | 832
juvenile dermatomyositis 7 | 1,189
Carney complex 6 | 23
Hypertension 6 | 287
Intellectual disability 6 | 573
Pituitary adenoma 6 | 35
Substance Withdrawal Syndrome 6 | 52
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,157
adrenocortical carcinoma 6 | 1,427
chronic rhinosinusitis 6 | 512
pancreatic carcinoma 6 | 567
tuberculosis 6 | 1,557
tuberculosis and treatment for 3 months 6 | 327
Alzheimer's disease 5 | 644
Beckwith-Wiedemann syndrome 5 | 46
Crohn's disease 5 | 304
Gastric ulcer 5 | 34
Gastritis 5 | 44
Heart disease 5 | 279
Hypertensive disease 5 | 193
Hyperthyroidism 5 | 50
Hypothyroidism 5 | 89
Kidney cancer 5 | 118
McCune Albright syndrome 5 | 19
Parkinson's disease 5 | 364
Peptic ulcer 5 | 22
Zollinger-Ellison Syndrome 5 | 14
dermatomyositis 5 | 933
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 532
Degenerative polyarthritis 4 | 93
Gastroesophageal reflux disease 4 | 37
Polycystic Ovary Syndrome 4 | 332
aldosterone-producing adenoma 4 | 664
head and neck cancer 4 | 270
mucosa-associated lymphoid tissue lymphoma 4 | 480
nephrosclerosis 4 | 329
spina bifida 4 | 1,064

Tissue

Blood and immune system 75 | 17,995
Digestive Tract 75 | 18,473
Endocrine System 75 | 18,512
Female tissues 75 | 18,647
Liver and Pancreas 75 | 18,136
Nervous System 75 | 18,561
Urinary Tract 75 | 18,444
Cardiovascular System 74 | 17,958
Male tissues 74 | 17,969
Respiratory system 74 | 17,484
Skin and soft tissues 73 | 18,115

Target Family

Non-IDG 17 | 11,971
Enzyme 14 | 4,146
Kinase 14 | 634
Transporter 14 | 473
Ion Channel 13 | 341
GPCR 4 | 406

KEGG Pathway

Gastric acid secretion 76 | 76
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/hydrogen exchanger 4 SLC9A4 Tdark Transporter -1.25841 17.4 6
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.76384 47.5 542
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Potassium-transporting ATPase subunit beta ATP4B Tclin Transporter -0.76953 6.01 159
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.58202 42.2 123
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.04732 117.9 108
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.09703 131.9 103
Somatostatin SST Tchem Non-IDG -4.13259 13272.3 348
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.66594 47.2 113
Cystic fibrosis transmembrane conductance regulator CFTR Tclin Ion Channel -3.74904 5988.4 267