Development Level

Tchem 27 | 1,885
Tbio 26 | 11,178
Tclin 21 | 612
Tdark 4 | 6,569

Collection

Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal bone structure 6 | 187
increased heart weight 4 | 62
increased startle reflex 4 | 112
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged gallbladder 1 | 2
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 62 | 11,192
ovarian cancer 41 | 8,297
psoriasis 39 | 6,514
glioblastoma 38 | 5,635
medulloblastoma, large-cell 38 | 6,086
atypical teratoid / rhabdoid tumor 35 | 4,971
adult high grade glioma 34 | 3,701
ependymoma 33 | 4,559
osteosarcoma 30 | 7,766
group 3 medulloblastoma 29 | 4,002
Astrocytoma, Pilocytic 27 | 3,006
lung cancer 27 | 4,607
primitive neuroectodermal tumor 26 | 2,957
Breast cancer 25 | 3,469
Kidney cancer 25 | 2,548
pancreatic cancer 24 | 2,322
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,204
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,872
oligodendroglioma 22 | 2,768
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,902
lung adenocarcinoma 20 | 2,627
astrocytic glioma 19 | 2,530
lung carcinoma 19 | 2,755
subependymal giant cell astrocytoma 19 | 2,230
Cancer 18 | 2,388
Epilepsy 16 | 775
Pick disease 16 | 1,856
malignant mesothelioma 16 | 3,135
Autosomal recessive predisposition 15 | 1,407
diabetes mellitus 15 | 1,683
pituitary cancer 15 | 1,915
Schizophrenia 14 | 1,136
interstitial cystitis 14 | 2,237
invasive ductal carcinoma 14 | 2,867
colon cancer 13 | 1,428
group 4 medulloblastoma 13 | 1,806
tuberculosis 13 | 1,963
ulcerative colitis 13 | 1,765
Bipolar Disorder 12 | 646
non-small cell lung cancer 12 | 2,799
Atrial Fibrillation 11 | 120
Hypertension 11 | 372
Liver cancer 11 | 589
Depressive disorder 10 | 401
Melanoma 10 | 689
astrocytoma 10 | 1,113
cystic fibrosis 10 | 1,629
Adenoma 9 | 159
Down syndrome 9 | 480
Duchenne muscular dystrophy 9 | 587
Intellectual disability 9 | 998
Skin cancer 9 | 451
Substance Withdrawal Syndrome 9 | 53
cutaneous lupus erythematosus 9 | 1,016
Dull intelligence 8 | 634
Kidney disease 8 | 411
Low intelligence 8 | 634
Mental Retardation 8 | 634
Mental deficiency 8 | 634
Obesity 8 | 655
Poor school performance 8 | 634
Rheumatoid arthritis 8 | 1,156
Seizures 8 | 584
primary pancreatic ductal adenocarcinoma 8 | 1,071
Acromegaly 7 | 48
Alzheimer's disease 7 | 640
Chronic heart failure 7 | 44
Congestive heart failure 7 | 109
Cushing's syndrome 7 | 47
Hypertensive disease 7 | 278
Major Depressive Disorder 7 | 293
Mental Depression 7 | 325
Multiple Endocrine Neoplasia Type 1 7 | 29
Poisoning by digitalis glycoside 7 | 8
Polycystic ovary syndrome 7 | 348
Unipolar Depression 7 | 244
breast carcinoma 7 | 1,589
ductal carcinoma in situ 7 | 1,686
gastric carcinoma 7 | 781
juvenile dermatomyositis 7 | 1,147
Carney complex 6 | 24
Cognitive delay 6 | 596
Constipation 6 | 174
Diarrhea 6 | 245
Gastritis 6 | 44
Global developmental delay 6 | 596
Heart disease 6 | 288
Hypothyroidism 6 | 115
Mental and motor retardation 6 | 596
Osteoporosis 6 | 348
Pituitary adenoma 6 | 37
Waldenstrons macroglobulinemia 6 | 742
acute quadriplegic myopathy 6 | 1,133
adrenocortical carcinoma 6 | 1,385
chronic rhinosinusitis 6 | 505
pancreatic carcinoma 6 | 555
Asthma 5 | 370
Crohn's disease 5 | 311
dermatomyositis 5 | 941
esophageal adenocarcinoma 5 | 696

Tissue

Endocrine System 75 | 18,159
Digestive Tract 74 | 17,369
Male tissues 74 | 17,142
Nervous System 73 | 16,725
Female tissues 72 | 17,400
Blood and immune system 71 | 16,909
Liver and Pancreas 71 | 16,750
Skin and soft tissues 71 | 17,230
Respiratory system 67 | 16,393
Urinary Tract 67 | 16,678
Cardiovascular System 61 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 14 | 4,145
Kinase 14 | 634
Transporter 14 | 473
Ion Channel 13 | 344
GPCR 4 | 408

KEGG Pathway

Gastric acid secretion 78 | 78
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 3 ADCY3 Tbio Enzyme -2.31593 204.4 82
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 PLCB4 Tbio Enzyme -1.77110 57.7 19
Potassium channel subfamily K member 2 KCNK2 Tclin Ion Channel -2.75349 578.2 86
Anion exchange transporter SLC26A7 Tbio Transporter -1.26445 19.4 41
Calmodulin-like protein 4 CALML4 Tdark Non-IDG 0.19 0.59 96
Inositol 1,4,5-trisphosphate receptor type 1 ITPR1 Tchem Ion Channel -2.75840 565.6 230
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.53936 363.5 246
Potassium channel subfamily K member 10 KCNK10 Tclin Ion Channel -1.75471 55.1 141
Calmodulin-like protein 6 CALML6 Tdark Non-IDG -0.42597 2.11 88