Development Level

Tchem 37 | 1,890
Tbio 27 | 10,625
Tclin 25 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 2 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

abnormal bone mineralization 5 | 55
abnormal bone structure 4 | 131
increased heart weight 4 | 37
abnormal behavior 3 | 226
preweaning lethality, complete... 3 | 633
abnormal spleen morphology 2 | 36
decreased body weight 2 | 174
preweaning lethality, incomple... 2 | 260
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal seminal vesicle morph... 1 | 47
abnormal vocalization 1 | 21
cataract 1 | 26
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 24
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
enlarged spleen 1 | 26
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased total body fat amoun... 1 | 57
male infertility 1 | 62
small epididymis 1 | 3
vertebral fusion 1 | 23

Disease

ovarian cancer 54 | 8,484
psoriasis 45 | 6,685
osteosarcoma 44 | 7,933
glioblastoma 43 | 5,572
medulloblastoma, large-cell 43 | 6,234
atypical teratoid / rhabdoid tumor 36 | 4,369
Carcinoma 33 | 2,147
Cancer 32 | 2,346
lung cancer 32 | 4,466
primitive neuroectodermal tumor 31 | 3,031
oligodendroglioma 30 | 2,849
pilocytic astrocytoma 30 | 3,086
Breast cancer 29 | 3,094
pancreatic cancer 28 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
malignant mesothelioma 25 | 3,162
lung carcinoma 24 | 2,844
non-small cell lung cancer 24 | 2,798
ependymoma 23 | 2,514
astrocytic glioma 22 | 2,241
lung adenocarcinoma 22 | 2,713
colon cancer 21 | 1,475
invasive ductal carcinoma 21 | 2,950
adult high grade glioma 20 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
Pick disease 19 | 1,893
ulcerative colitis 19 | 2,087
interstitial cystitis 18 | 2,299
pediatric high grade glioma 18 | 2,712
astrocytoma 17 | 1,493
breast carcinoma 17 | 1,614
group 4 medulloblastoma 17 | 1,875
pituitary cancer 16 | 1,972
subependymal giant cell astrocytoma 16 | 2,287
Obesity 15 | 616
group 3 medulloblastoma 15 | 2,254
medulloblastoma 15 | 1,524
primary pancreatic ductal adenocarcinoma 14 | 1,271
Hypertensive disorder 13 | 58
Neuroblastoma 13 | 78
juvenile dermatomyositis 13 | 1,189
Mammary Neoplasms 11 | 410
Schizophrenia 11 | 501
diabetes mellitus 11 | 1,663
tuberculosis 11 | 1,557
Duchenne muscular dystrophy 10 | 602
Ocular hypertension 10 | 27
Open-angle glaucoma 10 | 26
Parkinson's disease 10 | 364
cystic fibrosis 10 | 1,665
dermatomyositis 10 | 933
gastric carcinoma 10 | 832
Acute lymphoid leukemia 9 | 25
Adenoma 9 | 165
Anaplastic large T-cell systemic malignant lymphoma 9 | 10
Autistic Disorder 9 | 320
Burkitt's lymphoma 9 | 15
Carcinoma of breast 9 | 11
Carcinoma of female breast 9 | 20
Diffuse non-Hodgkin's lymphoma, large cell 9 | 12
Follicular non-Hodgkin's lymphoma 9 | 17
Gestational trophoblastic neoplasia 9 | 14
HER2-positive carcinoma of breast 9 | 10
Hodgkin's disease 9 | 18
Intellectual disability 9 | 573
Kaposi's sarcoma 9 | 20
Kidney disease 9 | 396
Langerhans cell histiocytosis, disseminated 9 | 10
Liposarcoma 9 | 20
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Malignant tumor of prostate 9 | 11
Malignant tumor of stomach 9 | 12
Malignant tumor of testis 9 | 11
Metastatic Breast Carcinoma 9 | 21
Metastatic Prostate Carcinoma 9 | 18
Multiple myeloma 9 | 1,327
Mycosis fungoides 9 | 28
Nephroblastoma 9 | 45
Non-Hodgkin's lymphoma 9 | 22
Noonan Syndrome 9 | 33
Rhabdomyosarcoma 9 | 29
Rheumatoid Arthritis 9 | 1,160
Secondary malignant neoplasm of pancreas 9 | 10
Transitional cell carcinoma 9 | 18
acute quadriplegic myopathy 9 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
posterior fossa group B ependymoma 9 | 1,530
Kidney cancer 8 | 118
Stomach Neoplasms 8 | 282
Substance Withdrawal Syndrome 8 | 52
adrenocortical carcinoma 8 | 1,427
atypical teratoid/rhabdoid tumor 8 | 1,095
ductal carcinoma in situ 8 | 1,745
nasopharyngeal carcinoma 8 | 1,056
pancreatic carcinoma 8 | 567
sonic hedgehog group medulloblastoma 8 | 1,482
spina bifida 8 | 1,064
cutaneous lupus erythematosus 7 | 1,056

Tissue

Cardiovascular System 89 | 17,958
Digestive Tract 89 | 18,473
Endocrine System 89 | 18,512
Female tissues 89 | 18,647
Liver and Pancreas 89 | 18,136
Nervous System 89 | 18,561
Urinary Tract 89 | 18,444
Male tissues 88 | 17,969
Respiratory system 88 | 17,484
Blood and immune system 87 | 17,995
Skin and soft tissues 86 | 18,115

Target Family

Non-IDG 37 | 11,971
Kinase 22 | 634
Enzyme 19 | 4,146
GPCR 9 | 406
Ion Channel 3 | 341

KEGG Pathway

Gap junction 90 | 90
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Tubulin beta-2A chain TUBB2A Tclin Non-IDG -1.58651 36.1 215
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.58202 42.2 123
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -2.99303 933.5 424
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.78634 57.0 688
Tubulin alpha-1A chain TUBA1A Tchem Non-IDG -1.55267 35.2 218
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.66594 47.2 113
Guanine nucleotide-binding protein G(i) subunit alpha-2 GNAI2 Tbio Non-IDG -1.23038 16.6 188
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.60410 3186.8 1232