Development Level

Tbio 17 | 11,651
Tchem 9 | 1,388
Tclin 4 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 21 | 11,493
ovarian cancer 17 | 8,520
osteosarcoma 13 | 7,950
glioblastoma 12 | 5,792
Autosomal recessive predisposition 11 | 1,442
psoriasis 11 | 6,694
malignant mesothelioma 9 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
pancreatic cancer 8 | 2,398
adult high grade glioma 7 | 3,801
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
tuberculosis 7 | 2,010
Cancer 6 | 2,499
Glycogen storage disease 6 | 39
Kidney cancer 6 | 2,613
ependymoma 6 | 4,679
Astrocytoma, Pilocytic 5 | 3,081
Diarrhea 5 | 253
Galactosemia 5 | 19
Hepatomegaly 5 | 285
Obesity 5 | 678
Osteoporosis 5 | 363
atypical teratoid / rhabdoid tumor 5 | 5,112
colon cancer 5 | 1,478
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
Cataract 4 | 297
Dull intelligence 4 | 645
Icterus 4 | 82
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Myocardial Ischemia 4 | 169
Neuropathy 4 | 261
Poor school performance 4 | 645
Splenomegaly 4 | 190
Type 2 diabetes mellitus 4 | 272
active ulcerative colitis 4 | 764
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
lung carcinoma 4 | 2,843
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Anemia 3 | 365
Breast cancer 3 | 3,578
Cognitive delay 3 | 608
Diabetes Mellitus, Experimental 3 | 108
Diabetes mellitus type 2 3 | 69
Epilepsy 3 | 792
Fabry disease 3 | 11
Failure to gain weight 3 | 365
Galactosemias 3 | 3
Galactosuria 3 | 4
Global developmental delay 3 | 608
Gout 3 | 104
Hypergalactosemia 3 | 3
Hyperglycemia 3 | 137
Hypoglycemia 3 | 152
Kidney disease 3 | 430
Lens Opacities 3 | 231
Melanoma 3 | 711
Mental and motor retardation 3 | 608
Metabolic acidosis 3 | 90
Muscle hypotonia 3 | 571
Myopathy 3 | 185
Pediatric failure to thrive 3 | 365
Short stature 3 | 531
Vomiting 3 | 116
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
invasive ductal carcinoma 3 | 2,951
primitive neuroectodermal tumor 3 | 3,035
Cerebrovascular disease 2 | 238
Corneal Opacity 2 | 53
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Hemoglobin low 2 | 124
Liver Dysfunction 2 | 99
Liver carcinoma 2 | 240
Nephrolithiasis 2 | 56
Neurodegenerative disease 2 | 414
Neurogenic Muscular Atrophy 2 | 139
Proteinuria 2 | 144
Seizures 2 | 596
Skin cancer 2 | 469
muscle degeneration 2 | 139

Tissue

Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 30 | 17,400
Blood and immune system 29 | 16,909
Male tissues 29 | 17,142
Liver and Pancreas 28 | 16,750
Skin and soft tissues 28 | 17,230
Urinary Tract 27 | 16,678
Nervous System 26 | 16,725
Respiratory system 25 | 16,393
Cardiovascular System 23 | 15,192

Target Family

Enzyme 22 | 4,145
Kinase 9 | 634

KEGG Pathway

Galactose metabolism 31 | 31
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent 6-phosphofructokinase, liver type PFKL Tbio Kinase -2.07015 107.6 240
ATP-dependent 6-phosphofructokinase, platelet type PFKP Tbio Kinase -1.93210 79.7 302
Hexokinase-3 HK3 Tbio Kinase -1.72467 51.4 355
Aldose reductase AKR1B1 Tclin Enzyme -3.27314 1915.8 350
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Lysosomal alpha-glucosidase GAA Tclin Enzyme -3.09870 1217.4 183
Glucokinase GCK Tchem Kinase -2.90428 758.6 336
Alpha-lactalbumin LALBA Tbio Enzyme -3.23301 1695.2 254
UTP--glucose-1-phosphate uridylyltransferase UGP2 Tbio Enzyme -2.53652 342.5 148
Putative hexokinase HKDC1 HKDC1 Tbio Kinase -0.76618 4.81 104