Development Level

Tbio 41 | 11,445
Tclin 25 | 613
Tchem 17 | 1,598
Tdark 5 | 6,588

Collection

Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal behavior 5 | 298
preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 5 | 499
hyperactivity 3 | 148
abnormal femur morphology 2 | 14
decreased fasted circulating g... 2 | 65
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
prenatal lethality 2 | 28
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal placenta vasculature 1 | 2
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cyanosis 1 | 7
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
hemorrhage 1 | 23
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating creatini... 1 | 38
prolonged PR interval 1 | 15
respiratory system phenotype 1 | 2
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 65 | 11,493
medulloblastoma, large-cell 57 | 6,241
glioblastoma 55 | 5,792
atypical teratoid / rhabdoid tumor 52 | 5,112
ependymoma 49 | 4,679
primitive neuroectodermal tumor 45 | 3,035
adult high grade glioma 43 | 3,801
group 3 medulloblastoma 42 | 4,104
ovarian cancer 41 | 8,520
Astrocytoma, Pilocytic 40 | 3,081
oligodendroglioma 38 | 2,850
osteosarcoma 38 | 7,950
lung carcinoma 34 | 2,843
psoriasis 34 | 6,694
Kidney cancer 31 | 2,613
Schizophrenia 31 | 1,160
subependymal giant cell astrocytoma 31 | 2,287
astrocytic glioma 30 | 2,597
Epilepsy 29 | 792
Breast cancer 23 | 3,578
Pick disease 23 | 1,894
Alcoholic Intoxication, Chronic 22 | 289
Bipolar Disorder 20 | 666
lung cancer 19 | 4,740
Anxiety 18 | 136
Autistic Disorder 18 | 364
invasive ductal carcinoma 18 | 2,951
pituitary cancer 17 | 1,972
General anesthesia 16 | 53
Insomnia 16 | 20
Tonic-clonic epilepsy 16 | 47
Depressive disorder 15 | 409
Mood Disorders 15 | 184
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
interstitial cystitis 14 | 2,312
pancreatic cancer 14 | 2,398
Mental Depression 13 | 333
Sedation as Adjunct to Anesthesia 13 | 15
lung adenocarcinoma 13 | 2,716
astrocytoma 12 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
non-small cell lung cancer 12 | 2,890
ulcerative colitis 12 | 1,819
Intellectual disability 11 | 1,016
Status Epilepticus 11 | 98
breast carcinoma 11 | 1,638
Alcohol dependence 10 | 107
Alcohol withdrawal syndrome 10 | 20
Seizures 10 | 596
group 4 medulloblastoma 10 | 1,855
malignant mesothelioma 10 | 3,232
Liver cancer 9 | 604
Major Depressive Disorder 9 | 301
Tetanus 9 | 68
colon cancer 9 | 1,478
diabetes mellitus 9 | 1,728
ductal carcinoma in situ 9 | 1,745
Alcohol withdrawal delirium 8 | 11
Autosomal recessive predisposition 8 | 1,442
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Generalized anxiety disorder 8 | 29
Induce Anterograde Amnesia 8 | 9
Irritable bowel syndrome 8 | 60
Local anesthesia 8 | 40
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Spasticity 8 | 26
Unipolar Depression 8 | 250
active Crohn's disease 8 | 922
tuberculosis 8 | 2,010
Anxiety associated with Menopause 7 | 7
Cognitive delay 7 | 608
Conscious sedation 7 | 10
Down syndrome 7 | 499
Feeling agitated 7 | 7
Global developmental delay 7 | 608
Liver Cirrhosis, Experimental 7 | 769
Mental and motor retardation 7 | 608
Mixed anxiety and depressive disorder 7 | 12
Panic disorder 7 | 61
Parkinson's disease 7 | 392
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic Ulcer 7 | 27
Pre-Op Apprehension 7 | 10
Rheumatoid arthritis 7 | 1,191
Schizoaffective Disorder 7 | 55
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
juvenile dermatomyositis 7 | 1,187
non primary Sjogren syndrome sicca 7 | 891
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Duchenne muscular dystrophy 6 | 601
Multiple myeloma 6 | 1,332
cutaneous lupus erythematosus 6 | 1,057
dermatomyositis 6 | 966
primary Sjogren syndrome 6 | 735

Tissue

Endocrine System 87 | 18,159
Nervous System 84 | 16,725
Digestive Tract 82 | 17,369
Blood and immune system 81 | 16,909
Male tissues 81 | 17,142
Skin and soft tissues 81 | 17,230
Female tissues 79 | 17,400
Urinary Tract 74 | 16,678
Liver and Pancreas 73 | 16,750
Respiratory system 70 | 16,393
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 27 | 12,091
Ion Channel 26 | 344
Enzyme 17 | 4,145
Transporter 9 | 473
Kinase 7 | 634
GPCR 2 | 408

KEGG Pathway

GABAergic synapse 88 | 88
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Sodium-coupled neutral amino acid transporter 5 SLC38A5 Tbio Transporter -3.03889 1061.8 77
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Sodium-coupled neutral amino acid transporter 3 SLC38A3 Tbio Transporter 0.00000 59
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.14287 1343.1 167
Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 Tbio Ion Channel -1.74365 53.9 92
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.13205 136.0 202
Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1 Tclin Ion Channel -1.79984 58.4 301
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114