Development Level

Tbio 21 | 11,445
Tchem 11 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal QT variability 2 | 10
decreased bone mineral density 2 | 126
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal kidney morphology 1 | 65
abnormal retinal vasculature m... 1 | 27
abnormal vocalization 1 | 21
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating magnesiu... 1 | 13
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24

Disease

Carcinoma 20 | 11,493
ovarian cancer 17 | 8,520
psoriasis 15 | 6,694
osteosarcoma 13 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung cancer 11 | 4,740
Autosomal recessive predisposition 10 | 1,442
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
active ulcerative colitis 8 | 764
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
lung adenocarcinoma 8 | 2,716
medulloblastoma, large-cell 8 | 6,241
Cancer 7 | 2,499
ductal carcinoma in situ 7 | 1,745
glioblastoma 7 | 5,792
malignant mesothelioma 7 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
adrenocortical carcinoma 6 | 1,428
ependymoma 6 | 4,679
lung carcinoma 6 | 2,843
Epilepsy 5 | 792
Icterus 5 | 82
Muscle hypotonia 5 | 571
Myocardial Ischemia 5 | 169
Seizures 5 | 596
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
invasive ductal carcinoma 5 | 2,951
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Adenocarcinoma of lung 4 | 142
Atopic dermatitis 4 | 952
Breast cancer 4 | 3,578
Cholelithiasis 4 | 33
Cognitive delay 4 | 608
Galactosemia 4 | 19
Global developmental delay 4 | 608
Glycogen storage disease 4 | 39
Hepatomegaly 4 | 285
Intellectual disability 4 | 1,016
Mental and motor retardation 4 | 608
Schizophrenia 4 | 1,160
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
fructose-1,6-bisphosphatase deficiency 4 | 7
interstitial cystitis 4 | 2,312
nasopharyngeal carcinoma 4 | 1,058
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Astrocytoma, Pilocytic 3 | 3,081
Cataract 3 | 297
Cholecystitis 3 | 18
Congenital disorder of glycosylation 3 | 54
Decreased tendon reflex 3 | 122
Diarrhea 3 | 253
Disease Models, Animal 3 | 155
Dull intelligence 3 | 645
Failure to gain weight 3 | 365
Hypoglycemia 3 | 152
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Muscle Weakness 3 | 170
Myopathy 3 | 185
Neuropathy 3 | 261
Normochromic anemia 3 | 6
Normocytic anemia 3 | 6
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Peripheral Neuropathy 3 | 134
Poor school performance 3 | 645
Splenomegaly 3 | 190
Vomiting 3 | 116
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
nephrosclerosis 3 | 333
primary pancreatic ductal adenocarcinoma 3 | 1,109
Carcinoma, Hepatocellular 2 | 228
Impaired exercise tolerance 2 | 42
Liver carcinoma 2 | 240
Mood Disorders 2 | 184
Neoplasm Invasiveness 2 | 161
Stomach Neoplasms 2 | 300
aldosterone-producing adenoma 2 | 665
fibroadenoma 2 | 559
mucosa-associated lymphoid tissue lymphoma 2 | 484
spina bifida 2 | 1,074

Tissue

Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Enzyme 21 | 4,145
Kinase 12 | 634

KEGG Pathway

Fructose and mannose metabolis... 33 | 33
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hexokinase-2 HK2 Tchem Kinase -2.64934 432.5 446
Sorbitol dehydrogenase SORD Tchem Enzyme -2.18880 132.4 347
Triokinase/FMN cyclase TKFC Tbio Enzyme -2.07992 116.2 109
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 PFKFB4 Tchem Enzyme -1.28108 21.2 110
Mannose-1-phosphate guanyltransferase alpha GMPPA Tbio Enzyme -1.64224 42.1 100
ATP-dependent 6-phosphofructokinase, muscle type PFKM Tbio Kinase -2.50086 308.0 311
Triosephosphate isomerase TPI1 Tbio Enzyme -2.88127 742.8 315
Phosphomannomutase 2 PMM2 Tchem Enzyme -2.12990 128.2 153
Fructose-1,6-bisphosphatase 1 FBP1 Tchem Enzyme -2.06824 111.8 202
Putative hexokinase HKDC1 HKDC1 Tbio Kinase -0.76618 4.81 104