Development Level

Tbio 12 | 11,178
Tchem 9 | 1,885
Tclin 5 | 612
Tdark 1 | 6,569

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased body length 2 | 101
decreased body weight 1 | 161
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278

Disease

Carcinoma 15 | 11,192
Autosomal recessive predisposition 12 | 1,407
malignant mesothelioma 12 | 3,135
medulloblastoma, large-cell 12 | 6,086
lung cancer 11 | 4,607
ovarian cancer 10 | 8,297
glioblastoma 9 | 5,635
osteosarcoma 9 | 7,766
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,911
Epilepsy 8 | 775
Seizures 8 | 584
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,204
non-small cell lung cancer 8 | 2,799
Bipolar Disorder 7 | 646
Cancer 7 | 2,388
Tremor 7 | 112
atypical teratoid / rhabdoid tumor 7 | 4,971
group 3 medulloblastoma 7 | 4,002
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,902
lung carcinoma 7 | 2,755
psoriasis 7 | 6,514
Cognitive delay 6 | 596
Global developmental delay 6 | 596
Infantile onset 6 | 236
Intellectual disability 6 | 998
Mental and motor retardation 6 | 596
Phenylketonuria 6 | 20
Rheumatoid arthritis 6 | 1,156
Small head 6 | 366
ependymoma 6 | 4,559
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,872
oligodendroglioma 6 | 2,768
Alcoholic Intoxication, Chronic 5 | 283
Dystonia 5 | 163
Highly variable severity 5 | 149
Hyperphenylalaninaemia 5 | 5
Irritation - emotion 5 | 67
Mood Disorders 5 | 181
Schizophrenia 5 | 1,136
Variable expressivity 5 | 149
adult high grade glioma 5 | 3,701
cystic fibrosis 5 | 1,629
ductal carcinoma in situ 5 | 1,686
interstitial cystitis 5 | 2,237
invasive ductal carcinoma 5 | 2,867
tuberculosis 5 | 1,963
Attention deficit hyperactivity disorder 4 | 272
Axial hypotonia 4 | 46
Choreoathetoid movements 4 | 32
Choreoathetosis 4 | 32
Colorectal Neoplasms 4 | 235
Depressive disorder 4 | 401
Dull intelligence 4 | 634
Dystonic disease 4 | 105
Endometriosis 4 | 521
Growth delay 4 | 112
Growth failure 4 | 112
Growth retardation 4 | 113
Hyperreflexia 4 | 208
Low intelligence 4 | 634
Major Depressive Disorder 4 | 293
Mental Retardation 4 | 634
Mental deficiency 4 | 634
Molybdenum Cofactor Deficiency, Complementation Group A 4 | 4
Muscle Hypertonia 4 | 88
Muscle hypotonia 4 | 562
Poor growth 4 | 112
Poor school performance 4 | 634
Unipolar Depression 4 | 244
Very poor growth 4 | 112
adrenocortical carcinoma 4 | 1,385
colon cancer 4 | 1,428
pituitary cancer 4 | 1,915
primitive neuroectodermal tumor 4 | 2,957
subependymal giant cell astrocytoma 4 | 2,230
Arthritis, Rheumatoid 3 | 169
Autistic Disorder 3 | 358
Carcinoma, Hepatocellular 3 | 217
Cerebral atrophy 3 | 175
Fever 3 | 136
Frontal bossing 3 | 154
Hypertension 3 | 372
Hypokinesia 3 | 19
Liver Cirrhosis, Experimental 3 | 733
Liver carcinoma 3 | 229
Mental Depression 3 | 325
Pick disease 3 | 1,856
Psychotic Disorders 3 | 150
Spontaneous abortion 3 | 97
active Crohn's disease 3 | 882
active ulcerative colitis 3 | 736
aldosterone-producing adenoma 3 | 646
astrocytic glioma 3 | 2,530
breast carcinoma 3 | 1,589
lung adenocarcinoma 3 | 2,627
nasopharyngeal carcinoma 3 | 1,024
nephrosclerosis 3 | 314
pancreatic cancer 3 | 2,322
posterior fossa group B ependymoma 3 | 406
ulcerative colitis 3 | 1,765

Tissue

Endocrine System 26 | 18,159
Digestive Tract 25 | 17,369
Female tissues 25 | 17,400
Blood and immune system 24 | 16,909
Nervous System 24 | 16,725
Skin and soft tissues 24 | 17,230
Liver and Pancreas 23 | 16,750
Urinary Tract 23 | 16,678
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Cardiovascular System 19 | 15,192

Target Family

Enzyme 25 | 4,145
Non-IDG 2 | 12,091

KEGG Pathway

Folate biosynthesis 27 | 27
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Folylpolyglutamate synthase, mitochondrial FPGS Tchem Enzyme -1.90018 79.8 131
Gephyrin GPHN Tbio Non-IDG -2.56617 383.9 235
Carbonyl reductase [NADPH] 1 CBR1 Tchem Enzyme -2.00623 106.8 274
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.80099 639.3 247
Sepiapterin reductase SPR Tbio Enzyme -1.58814 36.9 174
Molybdenum cofactor biosynthesis protein 1 MOCS1 Tbio Non-IDG -1.28570 20.9 138
Dihydrofolate reductase DHFR Tclin Enzyme -2.99192 972.8 202
Phenylalanine-4-hydroxylase PAH Tclin Enzyme -2.84378 662.6 193
Molybdopterin synthase catalytic subunit MOCS2 Tbio Enzyme -2.05483 207.6 92
Molybdenum cofactor sulfurase MOCOS Tbio Enzyme -1.10485 13.1 28