Development Level

Tbio 22 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased grip strength 1 | 116
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
increased circulating triglyce... 1 | 42
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 13 | 8,520
Carcinoma 11 | 11,493
osteosarcoma 10 | 7,950
psoriasis 9 | 6,694
ependymoma 8 | 4,679
medulloblastoma, large-cell 8 | 6,241
oligodendroglioma 8 | 2,850
Multiple myeloma 7 | 1,332
atypical teratoid / rhabdoid tumor 7 | 5,112
group 3 medulloblastoma 7 | 4,104
interstitial cystitis 7 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Autosomal recessive predisposition 6 | 1,442
Muscle hypotonia 6 | 571
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
tuberculosis 6 | 2,010
Breast cancer 5 | 3,578
Pick disease 5 | 1,894
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
Astrocytoma, Pilocytic 4 | 3,081
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Mental and motor retardation 4 | 608
Neurodegenerative disease 4 | 414
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
glioblastoma 4 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Cardiomyopathy, Dilated 3 | 83
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Heart failure 3 | 162
Hypoketotic hypoglycemia 3 | 11
Low intelligence 3 | 645
Medium chain acyl-CoA dehydrogenase deficiency 3 | 13
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Myoglobinuria 3 | 15
Obesity 3 | 678
Poor school performance 3 | 645
Very long chain acyl-CoA dehydrogenase deficiency 3 | 10
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
primitive neuroectodermal tumor 3 | 3,035
progressive supranuclear palsy 3 | 676
Acidosis, Lactic 2 | 97
Degenerative polyarthritis 2 | 115
Elevated hepatic transaminases 2 | 81
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Generalized muscle weakness 2 | 57
Hepatic enzyme increased 2 | 81
Hepatomegaly 2 | 285
Hypoglycemia 2 | 152
Ichthyosis 2 | 56
Lactic acidemia 2 | 95
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Low Birth Weights 2 | 69
Muscle Spasticity 2 | 195
Myocardial Ischemia 2 | 169
Neuropathy 2 | 261
Osteoarthritis 2 | 184
Pediatric failure to thrive 2 | 365
Retinal Degeneration 2 | 106
Rhabdomyolysis 2 | 15
Small for gestational age (disorder) 2 | 69
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
active ulcerative colitis 2 | 764
dermatomyositis 2 | 966
gastric cancer 2 | 459
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Enzyme 17 | 4,145
Non-IDG 8 | 12,091

KEGG Pathway

Fatty acid elongation 25 | 25
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acyl-coenzyme A thioesterase 4 ACOT4 Tbio Enzyme -0.53787 2.87 58
Acyl-coenzyme A thioesterase 1 ACOT1 Tdark Enzyme -2.14311 129.6 43
Very-long-chain 3-oxoacyl-CoA reductase HSD17B12 Tbio Enzyme -1.58879 36.7 136
Elongation of very long chain fatty acids protein 1 ELOVL1 Tbio Non-IDG -1.29305 16.7 156
Elongation of very long chain fatty acids protein 5 ELOVL5 Tbio Non-IDG -1.90493 83.7 237
Very-long-chain enoyl-CoA reductase TECR Tbio Enzyme -2.64230 415.5 102
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Palmitoyl-protein thioesterase 1 PPT1 Tbio Enzyme -2.63966 433.8 305
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 HACD2 Tbio Enzyme -0.37107 1.41 68
Elongation of very long chain fatty acids protein 7 ELOVL7 Tbio Non-IDG -0.75735 5.80 112