Development Level

Tbio 33 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal lens morphology 2 | 81
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal tibia morphology 1 | 14
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased body length 1 | 32
increased circulating bilirubi... 1 | 16
increased circulating phosphat... 1 | 26
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 35 | 11,493
ovarian cancer 24 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
psoriasis 21 | 6,694
Autosomal recessive predisposition 15 | 1,442
Muscle hypotonia 15 | 571
osteosarcoma 15 | 7,950
medulloblastoma, large-cell 14 | 6,241
lung cancer 13 | 4,740
ulcerative colitis 12 | 1,819
colon cancer 11 | 1,478
ductal carcinoma in situ 11 | 1,745
invasive ductal carcinoma 11 | 2,951
Alcohol dependence 9 | 107
Alcoholic Intoxication, Chronic 9 | 289
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Hypoglycemia 9 | 152
Mental and motor retardation 9 | 608
Obesity 9 | 678
astrocytoma 9 | 1,146
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
Epilepsy 8 | 792
Hepatomegaly 8 | 285
Seizures 8 | 596
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung adenocarcinoma 8 | 2,716
Multiple myeloma 7 | 1,332
glioblastoma 7 | 5,792
group 3 medulloblastoma 7 | 4,104
Alcohol abuse 6 | 50
Breast cancer 6 | 3,578
Elevated hepatic transaminases 6 | 81
Hepatic enzyme increased 6 | 81
Kidney cancer 6 | 2,613
Lethargy 6 | 77
Liver Dysfunction 6 | 99
Liver disease 6 | 237
Liver enzymes abnormal 6 | 81
Liver function test increased 6 | 81
Liver function tests abnormal finding 6 | 81
Medium chain acyl-CoA dehydrogenase deficiency 6 | 13
Subclinical abnormal liver function tests 6 | 81
Succinic semialdehyde dehydrogenase deficiency 6 | 16
Transaminases increased 6 | 81
Very long chain acyl-CoA dehydrogenase deficiency 6 | 10
acute myeloid leukemia 6 | 783
adult high grade glioma 6 | 3,801
beta-ketothiolase deficiency 6 | 13
lung carcinoma 6 | 2,843
non-small cell lung cancer 6 | 2,890
Atopic dermatitis 5 | 952
Carnitine palmitoyltransferase II deficiency 5 | 14
Dull intelligence 5 | 645
Failure to gain weight 5 | 365
Feeding difficulties in infancy 5 | 175
Hypoketotic hypoglycemia 5 | 11
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Pediatric failure to thrive 5 | 365
Poor school performance 5 | 645
Vomiting 5 | 116
Waldenstrons macroglobulinemia 5 | 765
active ulcerative colitis 5 | 764
adrenocortical carcinoma 5 | 1,428
tuberculosis 5 | 2,010
Cancer 4 | 2,499
Cardiomyopathy, Dilated 4 | 83
Coronary artery disease 4 | 268
Diabetes Mellitus, Experimental 4 | 108
Hyperammonemia 4 | 30
Lipid metabolism disorder 4 | 114
Multiple acyl-CoA dehydrogenase deficiency 4 | 25
Myoglobinuria 4 | 15
Pancreatitis 4 | 123
Rheumatoid arthritis 4 | 1,191
Short chain acyl-CoA dehydrogenase deficiency 4 | 9
Steatohepatitis 4 | 44
Zellweger syndrome 4 | 37
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
cystic fibrosis 4 | 1,696
esophageal adenocarcinoma 4 | 737
esophageal cancer 4 | 22
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
primitive neuroectodermal tumor 4 | 3,035
Bipolar Disorder 3 | 666
Pick disease 3 | 1,894
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Digestive Tract 44 | 17,369
Female tissues 44 | 17,400
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Endocrine System 43 | 18,159
Liver and Pancreas 43 | 16,750
Respiratory system 43 | 16,393
Blood and immune system 42 | 16,909
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Cardiovascular System 40 | 15,192

Target Family

Enzyme 40 | 4,145
Non-IDG 4 | 12,091

KEGG Pathway

Fatty acid degradation 44 | 44
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.98202 97.3 170
4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 Tbio Enzyme -1.43954 27.0 162
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Alcohol dehydrogenase class 4 mu/sigma chain ADH7 Tchem Enzyme -2.18765 159.0 243
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.97180 93.7 142
Alcohol dehydrogenase 6 ADH6 Tbio Enzyme -1.84121 71.7 117
Long-chain-fatty-acid--CoA ligase 6 ACSL6 Tbio Enzyme -1.86749 73.8 139
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM Tbio Enzyme -2.01557 101.4 321
Carnitine O-palmitoyltransferase 1, muscle isoform CPT1B Tchem Enzyme -2.33657 211.9 299
Alcohol dehydrogenase 4 ADH4 Tbio Enzyme -2.30746 247.9 210