Development Level

Tbio 17 | 11,445
Tchem 17 | 1,598
Tclin 6 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 2 | 220
cataract 2 | 92
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
abnormal body wall morphology 1 | 9
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased heart rate 1 | 18
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
hydrometra 1 | 53
increased body length 1 | 32
increased body weight 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased heart rate variabili... 1 | 7
microphthalmia 1 | 26
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small superior vagus ganglion 1 | 74

Disease

psoriasis 22 | 6,694
Carcinoma 19 | 11,493
diabetes mellitus 17 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Coronary artery disease 16 | 268
ovarian cancer 16 | 8,520
Atherosclerosis 15 | 291
Obesity 15 | 678
Lipid metabolism disorder 13 | 114
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
invasive ductal carcinoma 11 | 2,951
lung cancer 11 | 4,740
ductal carcinoma in situ 10 | 1,745
osteosarcoma 10 | 7,950
pancreatic cancer 10 | 2,398
Fatty liver disease 8 | 103
malignant mesothelioma 8 | 3,232
Autosomal recessive predisposition 7 | 1,442
Cancer 7 | 2,499
Cardiovascular system disease 7 | 246
Liver Cirrhosis, Experimental 7 | 769
non-small cell lung cancer 7 | 2,890
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
cystic fibrosis 6 | 1,696
interstitial cystitis 6 | 2,312
medulloblastoma, large-cell 6 | 6,241
ulcerative colitis 6 | 1,819
Breast cancer 5 | 3,578
Hypercholesterolemia 5 | 44
Hyperlipidemia 5 | 43
Sitosterolemia 5 | 9
Toxic encephalopathy 5 | 141
Xanthomatosis 5 | 12
adult high grade glioma 5 | 3,801
colon cancer 5 | 1,478
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
lung adenocarcinoma 5 | 2,716
pituitary cancer 5 | 1,972
Arthritis 4 | 290
Astrocytoma, Pilocytic 4 | 3,081
Cerebrovascular disease 4 | 238
Cholestasis 4 | 155
Kidney cancer 4 | 2,613
Kidney disease 4 | 430
Steatorrhea 4 | 34
Vascular disease 4 | 319
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
ependymoma 4 | 4,679
lung carcinoma 4 | 2,843
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Acute pancreatitis 3 | 10
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Coronary Disease 3 | 25
Coronary heart disease 3 | 16
Down syndrome 3 | 499
Familial hypercholesterolemia - homozygous 3 | 7
Gas gangrene 3 | 17
Heart disease 3 | 306
Hepatomegaly 3 | 285
Hypercholesterolemia, Familial 3 | 23
Hyperlipoproteinemia Type II 3 | 12
Hypertension 3 | 396
Hypertensive disease 3 | 292
Hypertriglyceridemia 3 | 17
Kidney Failure, Chronic 3 | 46
Liver disease 3 | 237
Membranous glomerulonephritis 3 | 13
Pancreatitis 3 | 123
Schizophrenia 3 | 1,160
Splenomegaly 3 | 190
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
cutaneous lupus erythematosus 3 | 1,057
group 4 medulloblastoma 3 | 1,855
oligodendroglioma 3 | 2,850
posterior fossa group B ependymoma 3 | 416
Anemia 2 | 365
Corneal Opacity 2 | 53
Electromyogram abnormal 2 | 49
Hemoglobin low 2 | 124
Liver cancer 2 | 604
Myocardial Ischemia 2 | 169
Polycystic ovary syndrome 2 | 360
Proteinuria 2 | 144
Reperfusion Injury 2 | 86
Stomach Neoplasms 2 | 300
Type 2 diabetes mellitus 2 | 272
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
fibroadenoma 2 | 559
head and neck cancer 2 | 271
pancreatic carcinoma 2 | 562
pterygium 2 | 76

Tissue

Digestive Tract 40 | 17,369
Female tissues 38 | 17,400
Endocrine System 37 | 18,159
Liver and Pancreas 37 | 16,750
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Blood and immune system 36 | 16,909
Male tissues 36 | 17,142
Nervous System 32 | 16,725
Respiratory system 31 | 16,393
Cardiovascular System 28 | 15,192

Target Family

Enzyme 28 | 4,145
Non-IDG 9 | 12,091
Transporter 4 | 473

KEGG Pathway

Fat digestion and absorption 41 | 41
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Diacylglycerol O-acyltransferase 2 DGAT2 Tchem Enzyme -2.07482 112.0 230
2-acylglycerol O-acyltransferase 3 MOGAT3 Tbio Enzyme -1.00860 10.7 81
Fatty acid-binding protein, intestinal FABP2 Tchem Non-IDG -2.54500 414.9 369
Group IIE secretory phospholipase A2 PLA2G2E Tchem Enzyme -0.44734 2.04 30
Phospholipase A2, membrane associated PLA2G2A Tchem Enzyme -2.83666 743.3 137
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.23630 1435.0 450
Group IIF secretory phospholipase A2 PLA2G2F Tchem Enzyme -0.17609 1.39 2
Calcium-dependent phospholipase A2 PLA2G5 Tchem Enzyme -1.38065 26.2 137