Development Level

Tbio 44 | 11,445
Tchem 20 | 1,598
Tclin 9 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryonic autopod pla... 1 | 2
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal placenta morphology 1 | 5
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
abnormal vibrissa morphology 1 | 25
decreased caudal vertebrae num... 1 | 53
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased vertical activity 1 | 24
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 44 | 11,493
psoriasis 43 | 6,694
Cancer 31 | 2,499
ovarian cancer 31 | 8,520
medulloblastoma, large-cell 24 | 6,241
glioblastoma 23 | 5,792
osteosarcoma 23 | 7,950
lung cancer 21 | 4,740
group 3 medulloblastoma 20 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
ependymoma 17 | 4,679
tuberculosis 17 | 2,010
Prostatic Neoplasms 16 | 495
Breast cancer 15 | 3,578
atypical teratoid / rhabdoid tumor 15 | 5,112
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Anemia 13 | 365
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
oligodendroglioma 12 | 2,850
primitive neuroectodermal tumor 12 | 3,035
ulcerative colitis 12 | 1,819
Autosomal recessive predisposition 11 | 1,442
Chemical and Drug Induced Liver Injury 11 | 195
Schizophrenia 10 | 1,160
colon cancer 10 | 1,478
invasive ductal carcinoma 10 | 2,951
non-small cell lung cancer 10 | 2,890
Carcinoma, Hepatocellular 9 | 228
Colorectal Neoplasms 9 | 243
Epilepsy 9 | 792
Liver carcinoma 9 | 240
Lung Neoplasms 9 | 232
Sickle Cell Anemia 9 | 53
adrenocortical carcinoma 9 | 1,428
adult high grade glioma 9 | 3,801
cystic fibrosis 9 | 1,696
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
lung adenocarcinoma 9 | 2,716
Bladder Neoplasm 8 | 112
Multiple myeloma 8 | 1,332
Urinary Bladder Neoplasms 8 | 114
diabetes mellitus 8 | 1,728
pancreatic cancer 8 | 2,398
Astrocytoma, Pilocytic 7 | 3,081
Bilirubin metabolic disorder 7 | 41
Neurodegenerative Disorders 7 | 79
Pericholangitis 7 | 8
astrocytic glioma 7 | 2,597
cutaneous lupus erythematosus 7 | 1,057
ductal carcinoma in situ 7 | 1,745
Breast Neoplasms 6 | 445
Diarrhea 6 | 253
Dull intelligence 6 | 645
Endometriosis 6 | 540
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Muscle hypotonia 6 | 571
Neurodegenerative Diseases 6 | 38
Neutropenia 6 | 72
Pick disease 6 | 1,894
Poor school performance 6 | 645
Waldenstrons macroglobulinemia 6 | 765
nasopharyngeal carcinoma 6 | 1,058
non-small cell lung carcinoma 6 | 317
pediatric high grade glioma 6 | 1,064
subependymal giant cell astrocytoma 6 | 2,287
Acute kidney injury 5 | 70
Adenocarcinoma of lung 5 | 142
Adverse reaction to drug 5 | 61
Autistic Disorder 5 | 364
Dihydropyrimidine dehydrogenase deficiency 5 | 6
Disease Models, Animal 5 | 155
Drug-Related Side Effects and Adverse Reactions 5 | 62
Hypertension 5 | 396
Kidney cancer 5 | 2,613
Liver Cirrhosis, Experimental 5 | 769
Liver disease 5 | 237
Non-alcoholic Fatty Liver Disease 5 | 42
Seizures 5 | 596
Stomach Neoplasms 5 | 300
acute quadriplegic myopathy 5 | 1,158
aldosterone-producing adenoma 5 | 665
breast carcinoma 5 | 1,638
esophageal adenocarcinoma 5 | 737
primary pancreatic ductal adenocarcinoma 5 | 1,109
Asthma 4 | 385
Atopic dermatitis 4 | 952
Attention deficit hyperactivity disorder 4 | 278
Colonic Neoplasms 4 | 142
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
hepatocellular carcinoma 4 | 547
nephrosclerosis 4 | 333
pituitary cancer 4 | 1,972

Tissue

Liver and Pancreas 73 | 16,750
Digestive Tract 72 | 17,369
Skin and soft tissues 71 | 17,230
Urinary Tract 71 | 16,678
Male tissues 69 | 17,142
Endocrine System 68 | 18,159
Female tissues 68 | 17,400
Blood and immune system 64 | 16,909
Respiratory system 59 | 16,393
Nervous System 58 | 16,725
Cardiovascular System 50 | 15,192

Target Family

Enzyme 64 | 4,145
Kinase 11 | 634
Non-IDG 2 | 12,091

KEGG Pathway

Drug metabolism - other enzyme... 77 | 77
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoside diphosphate kinase 7 NME7 Tbio Enzyme -0.83479 6.29 113
Uridine-cytidine kinase-like 1 UCKL1 Tdark Kinase -0.15970 2.21 110
UDP-glucuronosyltransferase 2A1 UGT2A2 Tdark Enzyme -0.95290 10.2 9
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.31570 219.0 131
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
Dihydropyrimidine dehydrogenase [NADP(+)] DPYD Tclin Enzyme -2.62432 395.0 159
UDP-glucuronosyltransferase 2B28 UGT2B28 Tbio Enzyme -0.88835 8.45 45
Glutathione S-transferase theta-2 GSTT2 Tbio Enzyme -1.25193 16.8 0
Inosine triphosphate pyrophosphatase ITPA Tbio Enzyme -2.54659 339.8 215
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945