Development Level

Tbio 64 | 11,445
Tclin 14 | 613
Tchem 10 | 1,598
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 14 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

increased startle reflex 7 | 112
preweaning lethality, complete... 7 | 979
increased heart weight 5 | 62
abnormal bone structure 4 | 187
decreased circulating glucose ... 3 | 126
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased eosinophil cell numb... 2 | 24
edema 2 | 59
hemorrhage 2 | 23
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
preweaning lethality, incomple... 2 | 499
prolonged PR interval 2 | 15
abnormal facial morphology 1 | 17
abnormal heart morphology 1 | 162
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal sensory capabilities-... 1 | 8
abnormal testis morphology 1 | 43
cyanosis 1 | 7
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating chloride... 1 | 41
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
respiratory system phenotype 1 | 2
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 76 | 11,493
glioblastoma 48 | 5,792
osteosarcoma 44 | 7,950
ovarian cancer 42 | 8,520
psoriasis 42 | 6,694
atypical teratoid / rhabdoid tumor 40 | 5,112
medulloblastoma, large-cell 36 | 6,241
adult high grade glioma 35 | 3,801
ependymoma 34 | 4,679
Astrocytoma, Pilocytic 33 | 3,081
Kidney cancer 33 | 2,613
lung carcinoma 31 | 2,843
lung cancer 30 | 4,740
pancreatic cancer 29 | 2,398
Autosomal recessive predisposition 28 | 1,442
Breast cancer 24 | 3,578
primitive neuroectodermal tumor 24 | 3,035
lung adenocarcinoma 23 | 2,716
non-small cell lung cancer 23 | 2,890
Cancer 22 | 2,499
group 3 medulloblastoma 22 | 4,104
invasive ductal carcinoma 22 | 2,951
Cardiomyopathy 21 | 116
oligodendroglioma 21 | 2,850
colon cancer 20 | 1,478
astrocytic glioma 19 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
malignant mesothelioma 19 | 3,232
Cardiomyopathy, Dilated 18 | 83
interstitial cystitis 18 | 2,312
Myopathy 17 | 185
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
pituitary cancer 17 | 1,972
Dilated cardiomyopathy 16 | 56
Liver cancer 16 | 604
Schizophrenia 16 | 1,160
diabetes mellitus 16 | 1,728
group 4 medulloblastoma 16 | 1,855
Bipolar Disorder 15 | 666
Hypertensive disease 15 | 292
Hypertrophic Cardiomyopathy 14 | 117
acute quadriplegic myopathy 14 | 1,158
cystic fibrosis 14 | 1,696
Familial isolated dilated cardiomyopathy 13 | 41
LEFT VENTRICULAR NONCOMPACTION 10 13 | 40
LEFT VENTRICULAR NONCOMPACTION 8 13 | 40
ductal carcinoma in situ 13 | 1,745
subependymal giant cell astrocytoma 13 | 2,287
tuberculosis 13 | 2,010
ulcerative colitis 13 | 1,819
Coronary artery disease 12 | 268
Heart disease 12 | 306
Heart failure 12 | 162
Hypertension 12 | 396
Liver Cirrhosis, Experimental 12 | 769
Pick disease 12 | 1,894
primary pancreatic ductal adenocarcinoma 12 | 1,109
Cardiomyopathies 11 | 110
Creatine phosphokinase serum increased 11 | 110
Depressive disorder 11 | 409
Elevated creatine kinase 11 | 110
Melanoma 11 | 711
Mental Depression 11 | 333
Muscle hypotonia 11 | 571
Muscular dystrophy 11 | 75
Myocardial Infarction 11 | 151
Skin cancer 11 | 469
Acquired scoliosis 10 | 281
Acute coronary syndrome 10 | 39
Cerebrovascular disease 10 | 238
Congestive heart failure 10 | 113
Curvature of spine 10 | 282
Duchenne muscular dystrophy 10 | 601
Epilepsy 10 | 792
Intellectual disability 10 | 1,016
Obesity 10 | 678
Osteoporosis 10 | 363
Prenatal onset 10 | 139
pediatric high grade glioma 10 | 1,064
Mood Disorders 9 | 184
Muscle biopsy shows dystrophic changes 9 | 39
Polycystic ovary syndrome 9 | 360
breast carcinoma 9 | 1,638
dermatomyositis 9 | 966
medulloblastoma 9 | 720
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Atrial Fibrillation 8 | 124
Dull intelligence 8 | 645
Endometrial cancer 8 | 311
Kidney disease 8 | 430
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Short stature 8 | 531
astrocytoma 8 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
cutaneous lupus erythematosus 8 | 1,057
limb-girdle muscular dystrophy 8 | 37

Tissue

Endocrine System 89 | 18,159
Digestive Tract 86 | 17,369
Male tissues 86 | 17,142
Nervous System 86 | 16,725
Blood and immune system 84 | 16,909
Female tissues 84 | 17,400
Skin and soft tissues 84 | 17,230
Urinary Tract 82 | 16,678
Liver and Pancreas 81 | 16,750
Respiratory system 80 | 16,393
Cardiovascular System 77 | 15,192

Target Family

Non-IDG 54 | 12,091
Ion Channel 21 | 344
Enzyme 10 | 4,145
Kinase 4 | 634
Transporter 2 | 473
GPCR 1 | 408

KEGG Pathway

Dilated cardiomyopathy (DCM) 92 | 92
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tbio Ion Channel -1.46356 25.4 471
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Emerin EMD Tbio Non-IDG -2.80459 640.6 299
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Titin TTN Tbio Kinase -3.24415 1743.0 123