Development Level

Tbio 156 | 10,625
Tchem 57 | 1,890
Tclin 45 | 602
Tdark 4 | 7,003

IMPC Term

preweaning lethality, complete... 8 | 633
preweaning lethality, incomple... 8 | 260
enlarged heart 6 | 111
decreased lean body mass 4 | 195
increased circulating total pr... 4 | 20
abnormal embryo size 3 | 112
decreased circulating insulin ... 3 | 75
decreased fasted circulating g... 3 | 49
decreased monocyte cell number 3 | 28
decreased total body fat amoun... 3 | 186
improved glucose tolerance 3 | 56
increased circulating HDL chol... 3 | 63
increased circulating alkaline... 3 | 119
increased circulating calcium ... 3 | 32
increased circulating serum al... 3 | 25
increased mean corpuscular vol... 3 | 91
abnormal bone structure 2 | 131
abnormal gait 2 | 51
abnormal seminal vesicle morph... 2 | 47
decreased CD8-positive, alpha-... 2 | 26
decreased NK T cell number 2 | 28
decreased T cell number 2 | 31
decreased alpha-beta T cell nu... 2 | 12
decreased bone mineral content 2 | 157
decreased caudal vertebrae num... 2 | 49
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased erythrocyte cell num... 2 | 43
decreased grip strength 2 | 123
decreased leukocyte cell numbe... 2 | 54
decreased lumbar vertebrae num... 2 | 62
enlarged epididymis 2 | 27
hypoactivity 2 | 89
increased circulating choleste... 2 | 53
increased circulating phosphat... 2 | 24
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 93
increased monocyte cell number 2 | 27
increased or absent threshold ... 2 | 128
limb grasping 2 | 35
small superior vagus ganglion 2 | 20
small testis 2 | 37
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal brain morphology 1 | 6
abnormal coat/ hair morphology 1 | 18
abnormal eye morphology 1 | 38
abnormal heart morphology 1 | 51
abnormal sleep behavior 1 | 63
craniofacial phenotype 1 | 9
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased heart rate 1 | 10
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased neutrophil cell numb... 1 | 37
decreased spleen weight 1 | 13
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hydroencephaly 1 | 6
hydrometra 1 | 13
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
lethargy 1 | 5
microphthalmia 1 | 15
prolonged RR interval 1 | 2
small adrenal glands 1 | 15
small seminal vesicle 1 | 6
vertebral fusion 1 | 23

Disease

psoriasis 143 | 6,685
Cancer 140 | 2,346
lung cancer 105 | 4,466
osteosarcoma 101 | 7,933
ovarian cancer 101 | 8,484
interstitial cystitis 89 | 2,299
ulcerative colitis 84 | 2,087
glioblastoma 81 | 5,572
lung carcinoma 79 | 2,844
tuberculosis 78 | 1,557
malignant mesothelioma 73 | 3,162
medulloblastoma, large-cell 64 | 6,234
Asthma 63 | 349
Rheumatoid Arthritis 62 | 1,160
lung adenocarcinoma 62 | 2,713
invasive ductal carcinoma 60 | 2,950
pilocytic astrocytoma 60 | 3,086
non-small cell lung cancer 59 | 2,798
Breast cancer 58 | 3,094
Hypersensitivity reaction type II disease 58 | 235
pancreatic cancer 58 | 2,300
Multiple Sclerosis 56 | 498
cutaneous lupus erythematosus 55 | 1,056
cystic fibrosis 55 | 1,665
Arthritis 46 | 248
atypical teratoid / rhabdoid tumor 45 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,988
adult high grade glioma 42 | 2,148
diabetes mellitus 42 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,956
pituitary cancer 42 | 1,972
Inflammatory bowel disease 41 | 142
Pneumonia 41 | 133
Kidney disease 40 | 396
Hypersensitivity 38 | 63
breast carcinoma 37 | 1,614
colon cancer 36 | 1,475
posterior fossa group A ependymoma 36 | 1,511
Atherosclerosis 32 | 275
Lung disease 32 | 132
Mammary Neoplasms 32 | 410
ductal carcinoma in situ 32 | 1,745
primary Sjogren syndrome 32 | 789
subependymal giant cell astrocytoma 32 | 2,287
Eosinophilia 31 | 65
Dermatitis 30 | 107
Influenza 30 | 142
Atopic dermatitis 29 | 944
Allergic hypersensitivity disease 28 | 123
nasopharyngeal carcinoma 28 | 1,056
periodontitis 28 | 269
sarcoidosis 28 | 358
active Crohn's disease 27 | 918
Liver disease 26 | 219
Pulmonary Fibrosis 26 | 66
gastric carcinoma 26 | 832
pediatric high grade glioma 26 | 2,712
group 4 medulloblastoma 25 | 1,875
hepatocellular carcinoma 25 | 532
oligodendroglioma 25 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,795
Carcinoma 24 | 2,147
Endometriosis 24 | 535
Anemia 23 | 252
Coronary artery disease 23 | 240
Hepatitis C 23 | 90
Human immunodeficiency virus infectious disease 23 | 92
Prostatic Neoplasms 23 | 471
mucosa-associated lymphoid tissue lymphoma 23 | 480
non-small cell lung carcinoma 23 | 413
primary pancreatic ductal adenocarcinoma 23 | 1,271
Crohn's disease 22 | 304
Heart disease 22 | 279
Inflammation 22 | 109
Obesity 22 | 616
Allergic rhinitis 21 | 91
Hepatitis B 21 | 103
juvenile dermatomyositis 21 | 1,189
Acquired immunodeficiency syndrome 20 | 164
Neoplasm Metastasis 20 | 138
Thrombocytopenia 20 | 105
Vascular disease 20 | 281
group 3 medulloblastoma 20 | 2,254
pancreatic carcinoma 20 | 567
Dermatitis, Atopic 19 | 45
Hypertension 19 | 287
adrenocortical carcinoma 19 | 1,427
Cerebrovascular disease 18 | 231
Diarrhea 18 | 155
Drug-Induced Liver Injury 18 | 118
Liver Cirrhosis, Experimental 18 | 108
Malaria 18 | 140
Peripheral Neuropathy 18 | 303
Brain Ischemia 17 | 87
Leishmaniasis 17 | 49
Myocardial Ischemia 17 | 169
Spontaneous abortion 17 | 108
astrocytoma 17 | 1,493
primitive neuroectodermal tumor 17 | 3,031

Tissue

Digestive Tract 253 | 18,473
Nervous System 251 | 18,561
Female tissues 250 | 18,647
Urinary Tract 247 | 18,444
Blood and immune system 245 | 17,995
Skin and soft tissues 245 | 18,115
Endocrine System 244 | 18,512
Liver and Pancreas 239 | 18,136
Cardiovascular System 237 | 17,958
Respiratory system 236 | 17,484
Male tissues 229 | 17,969

Target Family

Non-IDG 221 | 11,971
Kinase 20 | 634
GPCR 19 | 406
Enzyme 2 | 4,146

KEGG Pathway

Cytokine-cytokine receptor int... 262 | 262
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.34520 2413.2 212
Interferon lambda receptor 1 IFNLR1 Tchem Non-IDG -1.48464 33.1 128
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Interferon lambda-1 IFNL1 Tbio Non-IDG -1.90881 86.4 137
Lymphotoxin-alpha LTA Tbio Non-IDG -2.84770 612.8 461
Interleukin-1 receptor type 2 IL1R2 Tbio Non-IDG -1.85724 72.1 361
Interleukin-10 receptor subunit beta IL10RB Tbio Non-IDG -1.82576 55.5 177
Tumor necrosis factor receptor superfamily member 9 TNFRSF9 Tbio Non-IDG -2.71753 714.2 490