Development Level

Tbio 50 | 11,651
Tchem 18 | 1,388
Tclin 11 | 612

IMPC Phenotype

abnormal behavior 3 | 298
abnormal seminal vesicle morph... 3 | 114
enlarged heart 3 | 210
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased mean corpuscular vol... 2 | 79
hyperactivity 2 | 148
increased circulating sodium l... 2 | 71
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal placement of pupils 1 | 6
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
pale yolk sac 1 | 25
polycystic kidney 1 | 15
shortened PQ interval 1 | 7
shortened RR interval 1 | 17
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 64 | 11,493
ovarian cancer 45 | 8,520
lung cancer 44 | 4,740
lung carcinoma 42 | 2,843
Autosomal recessive predisposition 38 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,962
invasive ductal carcinoma 35 | 2,951
non-small cell lung cancer 34 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
Cancer 32 | 2,499
lung adenocarcinoma 31 | 2,716
psoriasis 31 | 6,694
glioblastoma 30 | 5,792
malignant mesothelioma 30 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
interstitial cystitis 26 | 2,312
Astrocytoma, Pilocytic 25 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
tuberculosis 25 | 2,010
ulcerative colitis 25 | 1,819
Kidney disease 23 | 430
pancreatic cancer 23 | 2,398
Breast cancer 21 | 3,578
Vascular disease 21 | 319
Thrombophilia 20 | 38
adult high grade glioma 20 | 3,801
osteosarcoma 20 | 7,950
Atherosclerosis 19 | 291
Cerebrovascular disease 19 | 238
cystic fibrosis 19 | 1,696
diabetes mellitus 19 | 1,728
ependymoma 19 | 4,679
adrenocortical carcinoma 18 | 1,428
medulloblastoma, large-cell 18 | 6,241
Coronary artery disease 17 | 268
Disseminated intravascular coagulation 17 | 38
Kidney cancer 17 | 2,613
Liver Cirrhosis, Experimental 17 | 769
Pulmonary embolism 17 | 55
atypical teratoid / rhabdoid tumor 17 | 5,112
Duchenne muscular dystrophy 16 | 601
Thrombosis 16 | 46
Venous Thrombosis 16 | 47
group 3 medulloblastoma 16 | 4,104
subependymal giant cell astrocytoma 16 | 2,287
Hypertension 15 | 396
breast carcinoma 15 | 1,638
colon cancer 15 | 1,478
ductal carcinoma in situ 15 | 1,745
Atopic dermatitis 14 | 952
Thrombocytopenia 14 | 197
esophageal adenocarcinoma 14 | 737
Anemia 13 | 365
Liver disease 13 | 237
Systemic lupus erythematosus 13 | 194
gastric carcinoma 13 | 807
Complement deficiency 12 | 14
pituitary cancer 12 | 1,972
Congenital afibrinogenemia 11 | 11
Liver Cirrhosis 11 | 181
Melanoma 11 | 711
Protein C deficiency 11 | 19
Rheumatoid arthritis 11 | 1,191
Schizophrenia 11 | 1,160
acute quadriplegic myopathy 11 | 1,158
dermatomyositis 11 | 966
limb girdle muscular dystrophy 2A 11 | 213
mucosa-associated lymphoid tissue lymphoma 11 | 484
oligodendroglioma 11 | 2,850
Age related macular degeneration 10 | 72
Epistaxis 10 | 43
Hemarthrosis 10 | 12
Hypersensitivity reaction type II disease 10 | 253
Hypertensive disease 10 | 292
Lupus Erythematosus, Systemic 10 | 67
Skin cancer 10 | 469
astrocytic glioma 10 | 2,597
astrocytoma 10 | 1,146
cutaneous lupus erythematosus 10 | 1,057
juvenile dermatomyositis 10 | 1,187
primary Sjogren syndrome 10 | 735
Angioedema 9 | 38
Arthritis 9 | 290
Chemical and Drug Induced Liver Injury 9 | 195
Ecchymosis 9 | 66
Heart disease 9 | 306
Hemophilia B 9 | 11
Immunologic Deficiency Syndromes 9 | 113
Increased tendency to bruise 9 | 66
fibroadenoma 9 | 559
head and neck cancer and chronic obstructive pulmonary disease 9 | 239
nasopharyngeal carcinoma 9 | 1,058
primary pancreatic ductal adenocarcinoma 9 | 1,109
Asthma 8 | 385
Becker muscular dystrophy 8 | 191
Lung disease 8 | 142
Peripheral vascular disease 8 | 87
Purpura 8 | 43
active ulcerative colitis 8 | 764
periodontitis 8 | 293

Tissue

Liver and Pancreas 79 | 16,750
Urinary Tract 78 | 16,678
Endocrine System 76 | 18,159
Digestive Tract 75 | 17,369
Female tissues 73 | 17,400
Male tissues 73 | 17,142
Skin and soft tissues 73 | 17,230
Blood and immune system 71 | 16,909
Respiratory system 71 | 16,393
Nervous System 68 | 16,725
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 19 | 4,145
GPCR 7 | 408
Transcription Factor 1 | 1,400

KEGG Pathway

Complement and coagulation cas... 79 | 79
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C4b-binding protein alpha chain C4BPA Tbio Non-IDG -2.43425 244.7 172
Complement component C9 C9 Tbio Non-IDG -1.88910 74.6 285
Complement C1q subcomponent subunit C C1QC Tbio Non-IDG -1.31972 17.9 168
Complement C1q subcomponent subunit B C1QB Tbio Non-IDG -1.66860 42.5 189
Complement C5 C5 Tclin Non-IDG -2.26690 170.8 448
Complement C3 C3 Tbio Non-IDG -3.55963 3446.1 1079
Alpha-2-macroglobulin A2M Tbio Non-IDG -2.96073 801.9 642
Antithrombin-III SERPINC1 Tclin Non-IDG -3.98451 9678.9 580
Kininogen-1 KNG1 Tchem Non-IDG -4.06379 11365.4 439
Mannose-binding protein C MBL2 Tbio Non-IDG -2.78880 522.8 359