Development Level

Tbio 19 | 11,445
Tchem 3 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 5 | 278
abnormal behavior 2 | 298
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased heart rate variabili... 1 | 7
increased or absent threshold ... 1 | 101
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 15 | 11,493
ovarian cancer 12 | 8,520
psoriasis 12 | 6,694
ependymoma 10 | 4,679
osteosarcoma 10 | 7,950
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
oligodendroglioma 8 | 2,850
Autosomal recessive predisposition 7 | 1,442
Osteopetrosis 7 | 43
astrocytic glioma 7 | 2,597
lung carcinoma 7 | 2,843
Failure to gain weight 6 | 365
Pediatric failure to thrive 6 | 365
Pick disease 6 | 1,894
primitive neuroectodermal tumor 6 | 3,035
Breast cancer 5 | 3,578
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
tuberculosis 5 | 2,010
Anemia 4 | 365
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
Metabolic acidosis 4 | 90
Nephrocalcinosis 4 | 35
Renal tubular acidosis 4 | 24
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Cutis Laxa 3 | 39
Dental caries 3 | 164
Distal Renal Tubular Acidosis 3 | 3
Dull intelligence 3 | 645
Epilepsy 3 | 792
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Osteoporosis 3 | 363
Poor school performance 3 | 645
RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE 3 | 3
Rotting teeth 3 | 73
Sensorineural Hearing Loss (disorder) 3 | 284
Sensorineural hearing loss 3 | 106
Short stature 3 | 531
Splenomegaly 3 | 190
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
malignant mesothelioma 3 | 3,232
mucosa-associated lymphoid tissue lymphoma 3 | 484
Barrett's esophagus 2 | 182
Bone pain 2 | 42
Broad flat nasal bridge 2 | 236
Cancer 2 | 2,499
Cerebrovascular disease 2 | 238
Compression of optic nerve 2 | 7
Dementia 2 | 175
Down syndrome 2 | 499
Frequent fractures 2 | 53
Frontal bossing 2 | 157
Gastroesophageal reflux disease 2 | 110
Gaucher disease type 1 2 | 180
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hemoglobin low 2 | 124
Hemolytic anemia 2 | 77
Hepatomegaly 2 | 285
Increased fracture rate 2 | 53
Kidney disease 2 | 430
Late tooth eruption 2 | 61
Motor delay 2 | 147
Nasal bridge wide 2 | 236
Nephrolithiasis 2 | 56
No development of motor milestones 2 | 147
Osteomalacia 2 | 35
Parkinson's disease 2 | 392
Poor growth 2 | 114
Prenatal onset 2 | 139
Pseudohypoaldosteronism 2 | 23
Rickets 2 | 49
Seizures 2 | 596
Stomach Neoplasms 2 | 300
Varying degree of multiple fractures 2 | 53
Very poor growth 2 | 114
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
lung adenocarcinoma 2 | 2,716
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 27 | 16,909
Male tissues 27 | 17,142
Urinary Tract 27 | 16,678
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Nervous System 26 | 16,725
Female tissues 25 | 17,400
Liver and Pancreas 24 | 16,750
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Cardiovascular System 23 | 15,192

Target Family

Enzyme 22 | 4,145
Transporter 4 | 473
Ion Channel 1 | 344

KEGG Pathway

Collecting duct acid secretion 27 | 27
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.23613 1628.1 165
Potassium-transporting ATPase subunit beta ATP4B Tclin Transporter -0.89031 7.06 189
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -1.04091 10.7 137
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.83801 66.4 144
V-type proton ATPase subunit E 2 ATP6V1E2 Tbio Enzyme -0.78312 6.53 60
V-type proton ATPase subunit F ATP6V1F Tbio Enzyme -0.91914 8.76 118
V-type proton ATPase subunit C 1 ATP6V1C1 Tbio Enzyme -1.31659 21.7 102
V-type proton ATPase subunit B, brain isoform ATP6V1B2 Tchem Enzyme -1.39933 24.1 157