Development Level

Tbio 23 | 10,625
Tclin 16 | 602
Tchem 13 | 1,890

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

abnormal bone mineralization 5 | 55
abnormal bone structure 5 | 131
increased heart weight 4 | 37
decreased lean body mass 3 | 195
abnormal behavior 2 | 226
decreased body weight 2 | 174
decreased circulating sodium l... 2 | 18
increased circulating alkaline... 2 | 119
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal neural tube closure 1 | 37
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 36
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased thermal nociceptive ... 1 | 4
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 260
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

glioblastoma 27 | 5,572
psoriasis 26 | 6,685
Parkinson's disease 24 | 364
Schizophrenia 24 | 501
medulloblastoma, large-cell 24 | 6,234
atypical teratoid / rhabdoid tumor 20 | 4,369
ovarian cancer 20 | 8,484
pilocytic astrocytoma 20 | 3,086
osteosarcoma 19 | 7,933
oligodendroglioma 18 | 2,849
pediatric high grade glioma 18 | 2,712
Toxic encephalopathy 17 | 131
primitive neuroectodermal tumor 17 | 3,031
Cancer 15 | 2,346
lung carcinoma 14 | 2,844
Bipolar Disorder 13 | 266
astrocytoma 13 | 1,493
pituitary cancer 13 | 1,972
Alzheimer's disease 12 | 644
lung cancer 12 | 4,466
Epilepsy 11 | 346
Obesity 11 | 616
ependymoma 11 | 2,514
ulcerative colitis 11 | 2,087
Alcohol dependence 10 | 107
Carcinoma 10 | 2,147
Cocaine-Related Disorders 10 | 88
Huntington's disease 10 | 72
Parkinsonism 10 | 19
Postencephalitic parkinsonism 10 | 12
group 4 medulloblastoma 10 | 1,875
invasive ductal carcinoma 10 | 2,950
medulloblastoma 10 | 1,524
pancreatic cancer 10 | 2,300
posterior fossa group A ependymoma 10 | 1,511
General anesthesia 9 | 53
Local anesthesia 9 | 40
Major Depressive Disorder 9 | 106
Pick disease 9 | 1,893
Substance abuse 9 | 55
breast carcinoma 9 | 1,614
colon cancer 9 | 1,475
Dementia 8 | 129
Parkinson Disease 8 | 102
astrocytic glioma 8 | 2,241
atypical teratoid/rhabdoid tumor 8 | 1,095
diabetes mellitus 8 | 1,663
subependymal giant cell astrocytoma 8 | 2,287
Alcoholism 7 | 14
Amphetamine-Related Disorders 7 | 74
Arteriosclerotic Parkinsonism 7 | 8
Attention deficit hyperactivity disorder 7 | 156
Autistic Disorder 7 | 320
Extrapyramidal disease 7 | 8
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Intellectual disability 7 | 573
Substance Withdrawal Syndrome 7 | 52
adult high grade glioma 7 | 2,148
lung adenocarcinoma 7 | 2,713
non-small cell lung cancer 7 | 2,798
Amyotrophic Lateral Sclerosis 6 | 431
Brain Ischemia 6 | 87
Brain disease 6 | 83
Breast cancer 6 | 3,094
Carney complex 6 | 23
Cocaine dependence 6 | 24
Dyskinesia, Drug-Induced 6 | 15
Heroin dependence 6 | 30
Hypotension 6 | 53
Nerve Degeneration 6 | 73
Rheumatoid Arthritis 6 | 1,160
aldosterone-producing adenoma 6 | 664
ductal carcinoma in situ 6 | 1,745
group 3 medulloblastoma 6 | 2,254
interstitial cystitis 6 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
malignant mesothelioma 6 | 3,162
Acromegaly 5 | 40
Adenoma 5 | 165
Cerebrovascular disease 5 | 231
Cushing's syndrome 5 | 47
Hyperactive behavior 5 | 31
Kidney disease 5 | 396
Opiate dependence 5 | 12
Parkinsonian Disorders 5 | 23
Pituitary adenoma 5 | 35
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
non primary Sjogren syndrome sicca 5 | 840
posterior fossa group B ependymoma 5 | 1,530
sonic hedgehog group medulloblastoma 5 | 1,482
Diabetes Mellitus, Non-Insulin-Dependent 4 | 157
Hypertensive disease 4 | 193
Hypothyroidism 4 | 89
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
nephrosclerosis 4 | 329
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
tuberculosis 4 | 1,557

Tissue

Blood and immune system 51 | 17,995
Cardiovascular System 51 | 17,958
Digestive Tract 51 | 18,473
Endocrine System 51 | 18,512
Female tissues 51 | 18,647
Liver and Pancreas 51 | 18,136
Male tissues 51 | 17,969
Nervous System 51 | 18,561
Respiratory system 51 | 17,484
Urinary Tract 51 | 18,444
Skin and soft tissues 49 | 18,115

Target Family

Transcription Factor 14 | 1,400
Non-IDG 12 | 11,971
Ion Channel 8 | 341
Enzyme 7 | 4,146
GPCR 4 | 406
Kinase 4 | 634
Transporter 3 | 473

KEGG Pathway

Cocaine addiction 52 | 52
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Cyclic AMP-responsive element-binding protein 3 CREB3 Tbio Transcription Factor -1.61736 42.0 159
G-protein-signaling modulator 1 GPSM1 Tbio Non-IDG -1.32467 28.6 99
Cyclic AMP-responsive element-binding protein 3-like protein 2 CREB3L2 Tbio Transcription Factor -2.46118 296.9 147
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.02975 1184.8 589
Guanine nucleotide-binding protein G(i) subunit alpha-2 GNAI2 Tbio Non-IDG -1.23038 16.6 188
Proenkephalin-B PDYN Tbio Non-IDG -3.47467 2966.3 161
Cyclic AMP-responsive element-binding protein 5 CREB5 Tbio Transcription Factor -0.80829 6.31 141
Glutamate receptor ionotropic, NMDA 2C GRIN2C Tclin Ion Channel -2.18626 145.4 176
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.37979 2431.7 224