Development Level

Tbio 24 | 11,651
Tclin 16 | 612
Tchem 12 | 1,388

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal bone structure 5 | 187
increased startle reflex 5 | 112
increased heart weight 4 | 62
decreased body weight 2 | 161
decreased circulating sodium l... 2 | 22
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal neural tube closure 1 | 46
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened QRS complex duration 1 | 1
tremors 1 | 39

Disease

Carcinoma 45 | 11,493
Schizophrenia 32 | 1,160
glioblastoma 29 | 5,792
atypical teratoid / rhabdoid tumor 26 | 5,112
psoriasis 26 | 6,694
Parkinson's disease 24 | 392
medulloblastoma, large-cell 24 | 6,241
ovarian cancer 23 | 8,520
Bipolar Disorder 21 | 666
ependymoma 21 | 4,679
Astrocytoma, Pilocytic 20 | 3,081
Depressive disorder 19 | 409
osteosarcoma 19 | 7,950
Alcoholic Intoxication, Chronic 18 | 289
Mental Depression 18 | 333
Toxic encephalopathy 18 | 141
adult high grade glioma 18 | 3,801
oligodendroglioma 18 | 2,850
group 3 medulloblastoma 17 | 4,104
lung cancer 17 | 4,740
primitive neuroectodermal tumor 17 | 3,035
Cancer 15 | 2,499
Major Depressive Disorder 14 | 301
Mood Disorders 14 | 184
lung carcinoma 14 | 2,843
Kidney cancer 13 | 2,613
pituitary cancer 13 | 1,972
Alzheimer's disease 12 | 658
Epilepsy 12 | 792
Breast cancer 11 | 3,578
Obesity 11 | 678
Unipolar Depression 11 | 250
astrocytic glioma 11 | 2,597
group 4 medulloblastoma 11 | 1,855
Alcohol dependence 10 | 107
Attention deficit hyperactivity disorder 10 | 278
Cocaine-Related Disorders 10 | 92
Huntington's disease 10 | 76
Parkinsonism 10 | 18
Postencephalitic parkinsonism 10 | 12
Substance Withdrawal Syndrome 10 | 55
astrocytoma 10 | 1,146
diabetes mellitus 10 | 1,728
invasive ductal carcinoma 10 | 2,951
pancreatic cancer 10 | 2,398
ulcerative colitis 10 | 1,819
General anesthesia 9 | 53
Local anesthesia 9 | 40
Pick disease 9 | 1,894
Substance abuse 9 | 59
breast carcinoma 9 | 1,638
colon cancer 9 | 1,478
Alcoholism 8 | 45
Cocaine Dependence 8 | 51
Dementia 8 | 175
Intellectual disability 8 | 1,016
Parkinson Disease 8 | 64
subependymal giant cell astrocytoma 8 | 2,287
Amphetamine-Related Disorders 7 | 74
Arteriosclerotic Parkinsonism 7 | 8
Autistic Disorder 7 | 364
Extrapyramidal disease 7 | 8
Hypotension 7 | 82
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Nerve Degeneration 7 | 121
Seizures 7 | 596
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
pediatric high grade glioma 7 | 1,064
Amyotrophic lateral sclerosis 6 | 451
Brain Ischemia 6 | 110
Brain disease 6 | 96
Carney complex 6 | 25
Dyskinesia, Drug-Induced 6 | 15
Heroin dependence 6 | 30
Hypertension 6 | 396
Hypertensive disease 6 | 292
Opiate dependence 6 | 29
Parkinsonian Disorders 6 | 56
Polycystic ovary syndrome 6 | 360
Rheumatoid arthritis 6 | 1,191
aldosterone-producing adenoma 6 | 665
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
malignant mesothelioma 6 | 3,232
substance-related disorder 6 | 162
Acromegaly 5 | 51
Adenoma 5 | 167
Autosomal recessive predisposition 5 | 1,442
Cerebrovascular disease 5 | 238
Cognitive delay 5 | 608
Cushing's syndrome 5 | 48
Kidney disease 5 | 430
Mental and motor retardation 5 | 608
Pituitary adenoma 5 | 38
Psychotic Disorders 5 | 151
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
tuberculosis 5 | 2,010

Tissue

Endocrine System 49 | 18,159
Digestive Tract 47 | 17,369
Female tissues 47 | 17,400
Skin and soft tissues 47 | 17,230
Blood and immune system 46 | 16,909
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Liver and Pancreas 44 | 16,750
Urinary Tract 44 | 16,678
Respiratory system 42 | 16,393
Cardiovascular System 36 | 15,192

Target Family

Transcription Factor 14 | 1,400
Non-IDG 12 | 12,091
Ion Channel 8 | 344
Enzyme 7 | 4,145
GPCR 4 | 408
Kinase 4 | 634
Transporter 3 | 473

KEGG Pathway

Cocaine addiction 52 | 52
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Protein fosB FOSB Tbio Transcription Factor -2.66286 432.2 328
Cyclic AMP-dependent transcription factor ATF-2 ATF2 Tbio Transcription Factor -2.23104 170.7 1819
Cyclic AMP-dependent transcription factor ATF-6 beta ATF6B Tbio Transcription Factor -1.03459 8.22 6
Cyclic AMP-responsive element-binding protein 5 CREB5 Tbio Transcription Factor -0.88055 7.80 164
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Guanine nucleotide-binding protein G(i) subunit alpha-1 GNAI1 Tbio Non-IDG -0.63224 3.23 220
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS Tbio Non-IDG -2.63356 1389.7 509
D(2) dopamine receptor DRD2 Tclin GPCR -3.28700 1882.2 264