Development Level

Tbio 34 | 10,625
Tchem 32 | 1,890
Tclin 23 | 602
Tdark 8 | 7,003

Collection

Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

abnormal bone mineralization 6 | 55
abnormal behavior 5 | 226
abnormal bone structure 5 | 131
preweaning lethality, incomple... 5 | 260
increased heart weight 4 | 37
abnormal spleen morphology 3 | 36
hyperactivity 3 | 108
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
impaired righting response 2 | 19
increased circulating alkaline... 2 | 119
increased startle reflex 2 | 38
preweaning lethality, complete... 2 | 633
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pancreas morphology 1 | 6
abnormal retinal blood vessel ... 1 | 18
abnormal retinal outer nuclear... 1 | 5
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal thoracic vertebrae mo... 1 | 16
abnormal urinary bladder morph... 1 | 2
abnormal vocalization 1 | 21
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased vertical activity 1 | 22
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
limb grasping 1 | 35
male infertility 1 | 62
small epididymis 1 | 3
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small superior vagus ganglion 1 | 20
thick ventricular wall 1 | 7
thrombocytopenia 1 | 46

Disease

medulloblastoma, large-cell 59 | 6,234
glioblastoma 57 | 5,572
psoriasis 47 | 6,685
atypical teratoid / rhabdoid tumor 45 | 4,369
ovarian cancer 45 | 8,484
osteosarcoma 44 | 7,933
primitive neuroectodermal tumor 44 | 3,031
pilocytic astrocytoma 39 | 3,086
lung carcinoma 34 | 2,844
pediatric high grade glioma 33 | 2,712
Carcinoma 32 | 2,147
oligodendroglioma 31 | 2,849
subependymal giant cell astrocytoma 31 | 2,287
ependymoma 28 | 2,514
Pick disease 27 | 1,893
Breast cancer 26 | 3,094
astrocytic glioma 25 | 2,241
lung cancer 25 | 4,466
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,988
lung adenocarcinoma 22 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
pituitary cancer 21 | 1,972
invasive ductal carcinoma 20 | 2,950
non-small cell lung cancer 20 | 2,798
Schizophrenia 19 | 501
group 3 medulloblastoma 19 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,289
malignant mesothelioma 19 | 3,162
Epilepsy 18 | 346
adult high grade glioma 18 | 2,148
medulloblastoma 18 | 1,524
pancreatic cancer 18 | 2,300
ulcerative colitis 18 | 2,087
colon cancer 17 | 1,475
astrocytoma 16 | 1,493
Substance Withdrawal Syndrome 15 | 52
group 4 medulloblastoma 15 | 1,875
posterior fossa group A ependymoma 14 | 1,511
posterior fossa group B ependymoma 14 | 1,530
Obesity 13 | 616
Parkinson's disease 13 | 364
interstitial cystitis 13 | 2,299
Cancer 12 | 2,346
atypical teratoid/rhabdoid tumor 12 | 1,095
breast carcinoma 12 | 1,614
Alzheimer's disease 11 | 644
Toxic encephalopathy 11 | 131
cystic fibrosis 11 | 1,665
diabetes mellitus 11 | 1,663
Cocaine-Related Disorders 10 | 88
Intellectual disability 10 | 573
Rheumatoid Arthritis 10 | 1,160
ductal carcinoma in situ 10 | 1,745
sonic hedgehog group medulloblastoma 10 | 1,482
General anesthesia 9 | 53
Local anesthesia 9 | 40
juvenile dermatomyositis 9 | 1,189
Autistic Disorder 8 | 320
Bipolar Disorder 8 | 266
Major Depressive Disorder 8 | 106
primary Sjogren syndrome 8 | 789
Amyotrophic Lateral Sclerosis 7 | 431
Hyperalgesia 7 | 71
Hypertensive disorder 7 | 58
Kidney cancer 7 | 118
Kidney disease 7 | 396
adrenocortical carcinoma 7 | 1,427
aldosterone-producing adenoma 7 | 664
gastric carcinoma 7 | 832
primary pancreatic ductal adenocarcinoma 7 | 1,271
tuberculosis and treatment for 3 months 7 | 327
Acquired metabolic disease 6 | 267
Adenoma 6 | 165
Alcohol dependence 6 | 107
Angina pectoris 6 | 21
Carney complex 6 | 23
Cerebrovascular disease 6 | 231
Crohn's disease 6 | 304
Duchenne muscular dystrophy 6 | 602
Heart disease 6 | 279
Hypertension 6 | 287
Hypertensive disease 6 | 193
Lennox-Gastaut syndrome 6 | 34
Morphine dependence 6 | 19
Neurodegenerative disease 6 | 383
Simple partial seizure 6 | 26
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,157
chronic rhinosinusitis 6 | 512
non primary Sjogren syndrome sicca 6 | 840
sarcoidosis 6 | 358
Cushing's syndrome 5 | 47
Juvenile arthritis 5 | 124
Prostatic Neoplasms 5 | 471
acute myeloid leukemia 5 | 780
cutaneous lupus erythematosus 5 | 1,056
esophageal adenocarcinoma 5 | 737
non-small cell lung carcinoma 5 | 413
progressive supranuclear palsy 5 | 674
spina bifida 5 | 1,064

Tissue

Digestive Tract 96 | 18,473
Endocrine System 96 | 18,512
Liver and Pancreas 96 | 18,136
Nervous System 96 | 18,561
Urinary Tract 96 | 18,444
Cardiovascular System 95 | 17,958
Female tissues 95 | 18,647
Blood and immune system 94 | 17,995
Male tissues 94 | 17,969
Skin and soft tissues 93 | 18,115
Respiratory system 92 | 17,484

Target Family

Non-IDG 34 | 11,971
Ion Channel 23 | 341
Enzyme 20 | 4,146
Kinase 15 | 634
GPCR 3 | 406
Transcription Factor 2 | 1,400

KEGG Pathway

Circadian entrainment 97 | 97
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.76384 47.5 542
Period circadian protein homolog 2 PER2 Tchem Non-IDG -2.62596 424.2 213
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.58202 42.2 123
Period circadian protein homolog 1 PER1 Tbio Non-IDG -1.79100 61.2 150
G protein-activated inward rectifier potassium channel 4 KCNJ5 Tchem Ion Channel -2.24687 186.6 114
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.31340 205.5 237
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 GNB2 Tbio Non-IDG -0.43889 2.98 102
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 Tbio Non-IDG -1.15715 18.1 144
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.09236 133.4 142