Development Level

Tbio 48 | 11,445
Tchem 36 | 1,598
Tclin 9 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
decreased body weight 3 | 161
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased circulating LDL chol... 2 | 38
decreased circulating creatini... 2 | 39
decreased total body fat amoun... 2 | 207
increased circulating LDL chol... 2 | 13
increased circulating alkaline... 2 | 122
increased grip strength 2 | 41
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
preweaning lethality, incomple... 2 | 499
thrombocytosis 2 | 27
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal hair growth 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal stomach morphology 1 | 10
decreased blood urea nitrogen ... 1 | 51
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hyperactivity 1 | 148
increased bone mineral content 1 | 108
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
short tibia 1 | 97

Disease

Carcinoma 78 | 11,493
osteosarcoma 57 | 7,950
ovarian cancer 54 | 8,520
glioblastoma 47 | 5,792
Cancer 45 | 2,499
psoriasis 45 | 6,694
medulloblastoma, large-cell 41 | 6,241
atypical teratoid / rhabdoid tumor 40 | 5,112
lung cancer 38 | 4,740
Breast cancer 36 | 3,578
ependymoma 32 | 4,679
group 3 medulloblastoma 30 | 4,104
invasive ductal carcinoma 27 | 2,951
malignant mesothelioma 27 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
adult high grade glioma 25 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
lung adenocarcinoma 24 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
pancreatic cancer 23 | 2,398
Astrocytoma, Pilocytic 22 | 3,081
Kidney cancer 22 | 2,613
non-small cell lung cancer 22 | 2,890
primitive neuroectodermal tumor 22 | 3,035
interstitial cystitis 21 | 2,312
lung carcinoma 21 | 2,843
Schizophrenia 20 | 1,160
oligodendroglioma 20 | 2,850
Epilepsy 18 | 792
Pick disease 18 | 1,894
breast carcinoma 18 | 1,638
ductal carcinoma in situ 18 | 1,745
Intellectual disability 17 | 1,016
astrocytic glioma 17 | 2,597
group 4 medulloblastoma 17 | 1,855
subependymal giant cell astrocytoma 17 | 2,287
cystic fibrosis 16 | 1,696
pituitary cancer 16 | 1,972
Breast Neoplasms 15 | 445
Mammary Neoplasms 15 | 425
Seizures 15 | 596
colon cancer 15 | 1,478
diabetes mellitus 15 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
ulcerative colitis 15 | 1,819
Dull intelligence 14 | 645
Low intelligence 14 | 645
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Poor school performance 14 | 645
Rheumatoid arthritis 14 | 1,191
adrenocortical carcinoma 14 | 1,428
Obesity 13 | 678
Stomach Neoplasms 13 | 300
Orbital separation excessive 12 | 244
astrocytoma 12 | 1,146
juvenile dermatomyositis 12 | 1,187
tuberculosis 12 | 2,010
Autosomal recessive predisposition 11 | 1,442
Blepharoptosis 11 | 231
Carcinoma, Hepatocellular 11 | 228
Cognitive delay 11 | 608
Depressive disorder 11 | 409
Downward slant of palpebral fissure 11 | 158
Global developmental delay 11 | 608
Hepatomegaly 11 | 285
Hypoplastic mandible condyle 11 | 275
Liver carcinoma 11 | 240
Lung Neoplasms 11 | 232
Mandibular hypoplasia 11 | 275
Mental and motor retardation 11 | 608
Micrognathism 11 | 275
Vascular disease 11 | 319
Acquired scoliosis 10 | 281
Bipolar Disorder 10 | 666
Byzanthine arch palate 10 | 194
Concave bridge of nose 10 | 195
Curvature of spine 10 | 282
Depressed nasal bridge 10 | 195
Depressed nasal root/bridge 10 | 195
High forehead 10 | 102
Kidney disease 10 | 430
Liver Cirrhosis, Experimental 10 | 769
Major Depressive Disorder 10 | 301
Muscle hypotonia 10 | 571
Neoplasm Metastasis 10 | 168
Renal Cell Carcinoma 10 | 214
Tall forehead 10 | 102
primary pancreatic ductal adenocarcinoma 10 | 1,109
Increased head circumference 9 | 147
Increased size of cranium 9 | 147
Increased size of skull 9 | 147
Melanoma 9 | 711
Parkinson's disease 9 | 392
Pectus excavatum 9 | 100
Short stature 9 | 531
Unipolar Depression 9 | 250
esophageal adenocarcinoma 9 | 737
pancreatic carcinoma 9 | 562
spina bifida 9 | 1,074

Tissue

Endocrine System 98 | 18,159
Digestive Tract 97 | 17,369
Female tissues 97 | 17,400
Male tissues 97 | 17,142
Skin and soft tissues 97 | 17,230
Nervous System 96 | 16,725
Liver and Pancreas 95 | 16,750
Urinary Tract 95 | 16,678
Blood and immune system 94 | 16,909
Respiratory system 94 | 16,393
Cardiovascular System 93 | 15,192

Target Family

Enzyme 33 | 4,145
Kinase 33 | 634
Non-IDG 17 | 12,091
Transporter 11 | 473
Transcription Factor 4 | 1,400

KEGG Pathway

Choline metabolism in cancer 98 | 98
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Diacylglycerol kinase eta DGKH Tbio Kinase -1.45863 29.5 92
Choline-phosphate cytidylyltransferase B PCYT1B Tbio Enzyme -1.46937 28.8 40
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Cholinephosphotransferase 1 CHPT1 Tbio Enzyme -1.42313 23.5 80
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Cytosolic phospholipase A2 gamma PLA2G4C Tchem Enzyme -1.27690 20.9 63
Choline transporter-like protein 4 SLC44A4 Tbio Transporter -1.67656 44.1 28
Choline-phosphate cytidylyltransferase A PCYT1A Tbio Enzyme -2.39713 242.7 191
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574