Development Level

Tbio 32 | 11,445
Tchem 17 | 1,598
Tclin 2 | 613

IMPC Phenotype

increased circulating choleste... 4 | 66
preweaning lethality, incomple... 4 | 499
increased circulating alkaline... 3 | 122
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
decreased bone mineral density 2 | 126
decreased circulating serum al... 2 | 82
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
preweaning lethality, complete... 2 | 979
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal tooth morphology 1 | 24
absent optic nerve 1 | 2
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased circulating unsatura... 1 | 1
increased exploration in new e... 1 | 8
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pallor 1 | 34
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small adrenal glands 1 | 16
thin ventricular wall 1 | 24

Disease

Atherosclerosis 31 | 291
Carcinoma 31 | 11,493
ovarian cancer 28 | 8,520
Coronary artery disease 26 | 268
psoriasis 24 | 6,694
Lipid metabolism disorder 23 | 114
glioblastoma 20 | 5,792
diabetes mellitus 19 | 1,728
osteosarcoma 19 | 7,950
Autosomal recessive predisposition 18 | 1,442
Obesity 18 | 678
atypical teratoid / rhabdoid tumor 18 | 5,112
Cardiovascular system disease 16 | 246
invasive ductal carcinoma 16 | 2,951
lung cancer 16 | 4,740
medulloblastoma, large-cell 16 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Hypercholesterolemia, Familial 14 | 23
ependymoma 14 | 4,679
Astrocytoma, Pilocytic 13 | 3,081
Hypercholesterolemia 13 | 44
ductal carcinoma in situ 13 | 1,745
malignant mesothelioma 13 | 3,232
adult high grade glioma 12 | 3,801
Kidney cancer 11 | 2,613
astrocytic glioma 11 | 2,597
oligodendroglioma 11 | 2,850
subependymal giant cell astrocytoma 11 | 2,287
Breast cancer 10 | 3,578
Hyperlipoproteinemia Type II 10 | 12
Serum cholesterol raised 10 | 22
group 3 medulloblastoma 10 | 4,104
lung adenocarcinoma 10 | 2,716
lung carcinoma 10 | 2,843
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
Alzheimer's disease 9 | 658
Cerebrovascular disease 9 | 238
Hyperlipidemia 9 | 43
Hypertension 9 | 396
Kidney disease 9 | 430
Liver Cirrhosis, Experimental 9 | 769
Splenomegaly 9 | 190
adrenocortical carcinoma 9 | 1,428
cystic fibrosis 9 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Cancer 8 | 2,499
Dyslipidemias 8 | 27
Hepatomegaly 8 | 285
Hypertensive disease 8 | 292
Myocardial Infarction 8 | 151
breast carcinoma 8 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Arcus Senilis 7 | 11
Cardiovascular Diseases 7 | 59
Down syndrome 7 | 499
Hyperlipoproteinemia Type IIa 7 | 11
Hypertriglyceridemia result 7 | 37
Schizophrenia 7 | 1,160
Type 2 diabetes mellitus 7 | 272
primitive neuroectodermal tumor 7 | 3,035
Cholestasis 6 | 155
Coronary Disease 6 | 25
Coronary heart disease 6 | 16
Heart disease 6 | 306
Hyperlipidemias 6 | 17
Low density lipoprotein increased 6 | 8
Vascular disease 6 | 319
Xanthomatosis 6 | 12
active Crohn's disease 6 | 922
active ulcerative colitis 6 | 764
interstitial cystitis 6 | 2,312
pediatric high grade glioma 6 | 1,064
tuberculosis 6 | 2,010
Amyloidosis 5 | 67
Angina Pectoris 5 | 32
Cholelithiasis 5 | 33
Epilepsy 5 | 792
Fatty liver disease 5 | 103
Hypercholesterolemia, Autosomal Dominant, Type B 5 | 5
Hypertriglyceridemia 5 | 17
Liver disease 5 | 237
Metabolic syndrome X 5 | 52
Sitosterolemia 5 | 9
astrocytoma 5 | 1,146
group 4 medulloblastoma 5 | 1,855
juvenile dermatomyositis 5 | 1,187
mucosa-associated lymphoid tissue lymphoma 5 | 484
ulcerative colitis 5 | 1,819
Anemia 4 | 365
Duchenne muscular dystrophy 4 | 601
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
fibroadenoma 4 | 559
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
pancreatic carcinoma 4 | 562
spina bifida 4 | 1,074

Tissue

Digestive Tract 50 | 17,369
Liver and Pancreas 50 | 16,750
Endocrine System 49 | 18,159
Female tissues 48 | 17,400
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678
Male tissues 47 | 17,142
Blood and immune system 45 | 16,909
Nervous System 43 | 16,725
Respiratory system 42 | 16,393
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 34 | 12,091
Enzyme 13 | 4,145
Transporter 4 | 473

KEGG Pathway

Cholesterol metabolism 51 | 51
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative peripheral benzodiazepine receptor-related protein TSPO Tchem Non-IDG -3.08695 2284.2 212
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.84388 738.4 199
Lysosomal acid lipase/cholesteryl ester hydrolase LIPA Tchem Enzyme -2.80202 616.3 170
Cholesterol 7-alpha-monooxygenase CYP7A1 Tbio Enzyme -2.70498 494.6 94
Voltage-dependent anion-selective channel protein 2 VDAC2 Tchem Non-IDG -1.89704 78.1 209
Cholesteryl ester transfer protein CETP Tchem Non-IDG -3.20658 1755.9 264
ATP-binding cassette sub-family G member 5 ABCG5 Tbio Transporter -2.29380 189.0 123