Development Level

Tbio 105 | 11,445
Tchem 55 | 1,598
Tclin 19 | 613
Tdark 4 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, incomple... 9 | 499
decreased total body fat amoun... 6 | 207
preweaning lethality, complete... 6 | 979
increased circulating alkaline... 5 | 122
abnormal retina morphology 4 | 71
decreased vertical activity 4 | 208
increased mean corpuscular hem... 4 | 96
thrombocytopenia 4 | 56
abnormal gait 3 | 69
decreased body weight 3 | 161
decreased circulating insulin ... 3 | 76
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased neutrophil cell numb... 3 | 46
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
decreased circulating creatini... 2 | 39
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
hydrometra 2 | 53
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal optic disc morphology 1 | 10
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
edema 1 | 59
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged RR interval 1 | 8
small kidney 1 | 16
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 104 | 11,493
ovarian cancer 100 | 8,520
Cancer 99 | 2,499
osteosarcoma 91 | 7,950
psoriasis 90 | 6,694
glioblastoma 76 | 5,792
lung cancer 70 | 4,740
medulloblastoma, large-cell 70 | 6,241
interstitial cystitis 64 | 2,312
lung carcinoma 59 | 2,843
ependymoma 58 | 4,679
atypical teratoid / rhabdoid tumor 57 | 5,112
Breast cancer 54 | 3,578
adult high grade glioma 52 | 3,801
malignant mesothelioma 49 | 3,232
invasive ductal carcinoma 48 | 2,951
non-small cell lung cancer 47 | 2,890
ulcerative colitis 45 | 1,819
tuberculosis 44 | 2,010
lung adenocarcinoma 43 | 2,716
Kidney cancer 39 | 2,613
Rheumatoid arthritis 39 | 1,191
Astrocytoma, Pilocytic 38 | 3,081
cutaneous lupus erythematosus 38 | 1,057
group 3 medulloblastoma 37 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,989
pancreatic cancer 36 | 2,398
subependymal giant cell astrocytoma 36 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,955
Asthma 34 | 385
cystic fibrosis 34 | 1,696
oligodendroglioma 33 | 2,850
diabetes mellitus 32 | 1,728
breast carcinoma 31 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
primitive neuroectodermal tumor 31 | 3,035
Arthritis 28 | 290
Multiple Sclerosis 27 | 540
Pick disease 27 | 1,894
colon cancer 27 | 1,478
astrocytic glioma 26 | 2,597
ductal carcinoma in situ 26 | 1,745
juvenile dermatomyositis 26 | 1,187
Pneumonia 24 | 174
Schizophrenia 24 | 1,160
primary Sjogren syndrome 24 | 735
Lung disease 23 | 142
group 4 medulloblastoma 23 | 1,855
Hypersensitivity 22 | 63
astrocytoma 21 | 1,146
Hypersensitivity reaction type II disease 20 | 253
Hypertension 20 | 396
Liver Cirrhosis, Experimental 20 | 769
Multiple myeloma 20 | 1,332
Vascular disease 20 | 319
pituitary cancer 20 | 1,972
Autosomal recessive predisposition 19 | 1,442
Bipolar Disorder 19 | 666
Breast Neoplasms 19 | 445
Mammary Neoplasms 19 | 425
Inflammatory bowel disease 18 | 151
active Crohn's disease 18 | 922
active ulcerative colitis 18 | 764
Atherosclerosis 17 | 291
Depressive disorder 17 | 409
Dermatitis 17 | 157
Kidney disease 17 | 430
Obesity 17 | 678
adrenocortical carcinoma 17 | 1,428
nasopharyngeal carcinoma 17 | 1,058
Prostatic Neoplasms 16 | 495
Short stature 16 | 531
hepatocellular carcinoma 16 | 547
sarcoidosis 16 | 370
Atopic dermatitis 15 | 952
Waldenstrons macroglobulinemia 15 | 765
periodontitis 15 | 293
primary pancreatic ductal adenocarcinoma 15 | 1,109
Brain Ischemia 14 | 110
Heart disease 14 | 306
Human immunodeficiency virus infectious disease 14 | 138
Intellectual disability 14 | 1,016
Melanoma 14 | 711
Mental Depression 14 | 333
dermatomyositis 14 | 966
head and neck cancer 14 | 271
mucosa-associated lymphoid tissue lymphoma 14 | 484
spina bifida 14 | 1,074
Acquired scoliosis 13 | 281
Byzanthine arch palate 13 | 194
Curvature of spine 13 | 282
Epilepsy 13 | 792
Hypertensive disease 13 | 292
Influenza 13 | 142
Orbital separation excessive 13 | 244
Seizures 13 | 596
esophageal adenocarcinoma 13 | 737
gastric carcinoma 13 | 807
head and neck cancer and chronic obstructive pulmonary disease 13 | 239
pediatric high grade glioma 13 | 1,064

Tissue

Endocrine System 183 | 18,159
Blood and immune system 181 | 16,909
Digestive Tract 181 | 17,369
Female tissues 179 | 17,400
Male tissues 179 | 17,142
Skin and soft tissues 179 | 17,230
Liver and Pancreas 178 | 16,750
Respiratory system 177 | 16,393
Urinary Tract 177 | 16,678
Nervous System 172 | 16,725
Cardiovascular System 163 | 15,192

Target Family

Non-IDG 92 | 12,091
Kinase 42 | 634
Enzyme 24 | 4,145
GPCR 18 | 408
Transcription Factor 7 | 1,400

KEGG Pathway

Chemokine signaling pathway 183 | 183
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
C-C motif chemokine 3-like 1 CCL3L1 Tbio Non-IDG -1.80717 51.3 142
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
C-C motif chemokine 13 CCL13 Tbio Non-IDG -2.02640 99.2 264
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Rhodopsin kinase GRK7 Tchem Kinase -1.83396 45.0 180
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
C-X-C chemokine receptor type 2 CXCR2 Tchem GPCR -2.87313 723.9 643
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.48051 278.1 378