Development Level

Tchem 38 | 1,890
Tbio 29 | 10,625
Tclin 9 | 602
Tdark 3 | 7,003

IMPC Term

abnormal coat/hair pigmentatio... 1 | 54
abnormal heart left ventricle ... 1 | 20
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
absent vibrissae 1 | 14
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating triglyce... 1 | 83
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased spleen weight 1 | 13
increased IgA level 1 | 1
increased circulating potassiu... 1 | 31
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
preweaning lethality, incomple... 1 | 260
thrombocytopenia 1 | 46

Disease

psoriasis 45 | 6,685
Cancer 36 | 2,346
Prostatic Neoplasms 25 | 471
ovarian cancer 25 | 8,484
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
glioblastoma 19 | 5,572
osteosarcoma 19 | 7,933
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
medulloblastoma, large-cell 18 | 6,234
lung carcinoma 17 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,795
malignant mesothelioma 16 | 3,162
non-small cell lung cancer 14 | 2,798
tuberculosis 14 | 1,557
Drug-Induced Liver Injury 13 | 118
Liver disease 13 | 219
interstitial cystitis 13 | 2,299
lung adenocarcinoma 13 | 2,713
lung cancer 13 | 4,466
ulcerative colitis 12 | 2,087
Breast cancer 11 | 3,094
adrenocortical carcinoma 11 | 1,427
atypical teratoid / rhabdoid tumor 11 | 4,369
invasive ductal carcinoma 11 | 2,950
nasopharyngeal carcinoma 11 | 1,056
Lung Neoplasms 10 | 171
diabetes mellitus 10 | 1,663
esophageal adenocarcinoma 10 | 737
pancreatic cancer 10 | 2,300
oligodendroglioma 9 | 2,849
pituitary cancer 9 | 1,972
Alcohol dependence 8 | 107
Anemia 8 | 252
Colorectal Neoplasms 8 | 217
Liver carcinoma 8 | 217
cystic fibrosis 8 | 1,665
ductal carcinoma in situ 8 | 1,745
head and neck cancer and chronic obstructive pulmonary disease 8 | 237
subependymal giant cell astrocytoma 8 | 2,287
Adverse reaction to drug 7 | 54
Bilirubin metabolic disorder 7 | 39
Bladder Neoplasm 7 | 109
Pericholangitis 7 | 7
colon cancer 7 | 1,475
primitive neuroectodermal tumor 7 | 3,031
Acute kidney injury 6 | 65
Attention deficit hyperactivity disorder 6 | 156
Chromosome Aberrations 6 | 15
Contact Dermatitis 6 | 80
Endometriosis 6 | 535
Hypertensive disease 6 | 193
Liver Cirrhosis, Experimental 6 | 108
Mammary Neoplasms 6 | 410
Neurodegenerative Disorders 6 | 37
Obesity 6 | 616
Precursor Cell Lymphoblastic Leukemia Lymphoma 6 | 42
Rheumatoid Arthritis 6 | 1,160
aldosterone-producing adenoma 6 | 664
breast carcinoma 6 | 1,614
non primary Sjogren syndrome sicca 6 | 840
non-small cell lung carcinoma 6 | 413
pediatric high grade glioma 6 | 2,712
Asthma 5 | 349
Epilepsy 5 | 346
Micronuclei, Chromosome-Defective 5 | 19
Mouth Neoplasms 5 | 42
Multiple myeloma 5 | 1,327
Pancreatitis 5 | 97
Peripheral Neuropathy 5 | 303
Pick disease 5 | 1,893
Squamous cell carcinoma of esophagus 5 | 82
acute myeloid leukemia 5 | 780
astrocytic glioma 5 | 2,241
cutaneous lupus erythematosus 5 | 1,056
ependymoma 5 | 2,514
gastric carcinoma 5 | 832
group 3 medulloblastoma 5 | 2,254
pilocytic astrocytoma 5 | 3,086
primary pancreatic ductal adenocarcinoma 5 | 1,271
Adenoma 4 | 165
Amphetamine-Related Disorders 4 | 74
Atherosclerosis 4 | 275
Atopic dermatitis 4 | 944
Autistic Disorder 4 | 320
Chronic obstructive pulmonary disease 4 | 146
Colonic Neoplasms 4 | 126
Coronary artery disease 4 | 240
Drug allergy 4 | 36
Hypertension 4 | 287
Myocardial Ischemia 4 | 169
Pain agnosia 4 | 99
Schizophrenia 4 | 501
Stomach Neoplasms 4 | 282
active Crohn's disease 4 | 918
adrenocortical adenoma 4 | 134
adult high grade glioma 4 | 2,148
fibroadenoma 4 | 557
sonic hedgehog group medulloblastoma 4 | 1,482
substance-related disorder 4 | 105

Tissue

Digestive Tract 79 | 18,473
Liver and Pancreas 79 | 18,136
Urinary Tract 79 | 18,444
Blood and immune system 76 | 17,995
Endocrine System 74 | 18,512
Female tissues 74 | 18,647
Nervous System 73 | 18,561
Skin and soft tissues 72 | 18,115
Male tissues 70 | 17,969
Cardiovascular System 67 | 17,958
Respiratory system 67 | 17,484

Target Family

Enzyme 68 | 4,146
Non-IDG 10 | 11,971
Transcription Factor 1 | 1,400

KEGG Pathway

Chemical carcinogenesis 79 | 79
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutathione S-transferase A5 GSTA5 Tdark Enzyme -1.03093 10.6 28
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
Alcohol dehydrogenase 1B ADH1B Tclin Enzyme -2.54721 366.0 136
Alcohol dehydrogenase 1C ADH1C Tclin Enzyme 366.0 73
UDP-glucuronosyltransferase 2B10 UGT2B10 Tchem Enzyme -1.11329 16.8 81
Arylamine N-acetyltransferase 2 NAT2 Tchem Enzyme -2.71360 546.9 245
Aryl hydrocarbon receptor nuclear translocator ARNT Tbio Transcription Factor -2.49893 243.3 424
Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 Tclin Enzyme -2.86650 850.3 270
UDP-glucuronosyltransferase 2B15 UGT2B15 Tchem Enzyme -1.76635 60.2 66
Sulfotransferase 1A3 SULT1A3 Tchem Enzyme -2.34317 249.1 106