Development Level

Tbio 47 | 11,651
Tchem 20 | 1,388
Tclin 9 | 612
Tdark 3 | 6,593

IMPC Phenotype

hyperactivity 3 | 148
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
enlarged heart 1 | 210
increased IgA level 1 | 1
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56

Disease

Carcinoma 48 | 11,493
psoriasis 45 | 6,694
Cancer 37 | 2,499
Prostatic Neoplasms 25 | 495
ovarian cancer 25 | 8,520
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
glioblastoma 19 | 5,792
osteosarcoma 19 | 7,950
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
medulloblastoma, large-cell 18 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Chemical and Drug Induced Liver Injury 17 | 195
lung carcinoma 17 | 2,843
malignant mesothelioma 17 | 3,232
Schizophrenia 15 | 1,160
non-small cell lung cancer 15 | 2,890
Liver disease 14 | 237
lung cancer 14 | 4,740
tuberculosis 14 | 2,010
Alcoholic Intoxication, Chronic 13 | 289
Breast cancer 13 | 3,578
interstitial cystitis 13 | 2,312
lung adenocarcinoma 13 | 2,716
adrenocortical carcinoma 11 | 1,428
atypical teratoid / rhabdoid tumor 11 | 5,112
diabetes mellitus 11 | 1,728
invasive ductal carcinoma 11 | 2,951
nasopharyngeal carcinoma 11 | 1,058
ulcerative colitis 11 | 1,819
ependymoma 10 | 4,679
esophageal adenocarcinoma 10 | 737
pancreatic cancer 10 | 2,398
Hypertension 9 | 396
Lung Neoplasms 9 | 232
Sickle Cell Anemia 9 | 53
group 3 medulloblastoma 9 | 4,104
head and neck cancer and chronic obstructive pulmonary disease 9 | 239
oligodendroglioma 9 | 2,850
pituitary cancer 9 | 1,972
Alcohol dependence 8 | 107
Anemia 8 | 365
Carcinoma, Hepatocellular 8 | 228
Colorectal Neoplasms 8 | 243
Drug-Related Side Effects and Adverse Reactions 8 | 62
Liver Cirrhosis, Experimental 8 | 769
Liver carcinoma 8 | 240
Melanoma 8 | 711
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
subependymal giant cell astrocytoma 8 | 2,287
Adverse reaction to drug 7 | 61
Bilirubin metabolic disorder 7 | 41
Bladder Neoplasm 7 | 112
Pericholangitis 7 | 8
Urinary Bladder Neoplasms 7 | 114
adult high grade glioma 7 | 3,801
colon cancer 7 | 1,478
primitive neuroectodermal tumor 7 | 3,035
Acute kidney injury 6 | 70
Alcohol abuse 6 | 50
Attention deficit hyperactivity disorder 6 | 278
Autosomal recessive predisposition 6 | 1,442
Breast Neoplasms 6 | 445
Chromosome Aberrations 6 | 16
Contact Dermatitis 6 | 81
Dermatitis, Contact 6 | 71
Endometriosis 6 | 540
Epilepsy 6 | 792
Hypertensive disease 6 | 292
Mammary Neoplasms 6 | 425
Neurodegenerative Diseases 6 | 38
Neurodegenerative Disorders 6 | 79
Non-alcoholic Fatty Liver Disease 6 | 42
Obesity 6 | 678
Precursor Cell Lymphoblastic Leukemia Lymphoma 6 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 6 | 49
Rheumatoid arthritis 6 | 1,191
aldosterone-producing adenoma 6 | 665
breast carcinoma 6 | 1,638
non primary Sjogren syndrome sicca 6 | 891
Asthma 5 | 385
Astrocytoma, Pilocytic 5 | 3,081
Cholestasis 5 | 155
Chronic obstructive pulmonary disease 5 | 184
Depressive disorder 5 | 409
Esophageal Squamous Cell Carcinoma 5 | 77
Major Depressive Disorder 5 | 301
Mental Depression 5 | 333
Mouth Neoplasms 5 | 55
Multiple myeloma 5 | 1,332
Pick disease 5 | 1,894
Squamous cell carcinoma of esophagus 5 | 77
Unipolar Depression 5 | 250
Vascular disease 5 | 319
Xeroderma pigmentosum group D 5 | 33
acute myeloid leukemia 5 | 783
astrocytic glioma 5 | 2,597
cutaneous lupus erythematosus 5 | 1,057
gastric carcinoma 5 | 807

Tissue

Liver and Pancreas 75 | 16,750
Digestive Tract 73 | 17,369
Skin and soft tissues 72 | 17,230
Urinary Tract 71 | 16,678
Female tissues 69 | 17,400
Endocrine System 67 | 18,159
Male tissues 67 | 17,142
Blood and immune system 63 | 16,909
Respiratory system 61 | 16,393
Nervous System 55 | 16,725
Cardiovascular System 43 | 15,192

Target Family

Enzyme 68 | 4,145
Non-IDG 10 | 12,091
Transcription Factor 1 | 1,400

KEGG Pathway

Chemical carcinogenesis 79 | 79
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 Tchem Enzyme -2.12624 141.3 310
Microsomal glutathione S-transferase 2 MGST2 Tbio Enzyme -1.15686 13.6 120
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.54987 3641.5 384
Aryl hydrocarbon receptor nuclear translocator ARNT Tbio Transcription Factor -2.53687 261.2 474
Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 Tclin Enzyme -2.90022 890.0 302
Glutathione S-transferase theta-2B GSTT2B Tbio Enzyme -1.34935 21.5 93
Glutathione S-transferase theta-1 GSTT1 Tbio Enzyme -2.93405 876.1 0
Glutathione S-transferase kappa 1 GSTK1 Tchem Enzyme -1.09202 13.0 253
Sulfotransferase 1A2 SULT1A2 Tbio Enzyme -1.83327 67.4 60