Development Level

Tchem 31 | 1,890
Tbio 20 | 10,625
Tclin 16 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
decreased body weight 3 | 174
abnormal gait 2 | 51
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating creatini... 2 | 31
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
increased circulating LDL chol... 2 | 15
increased circulating choleste... 2 | 53
increased mean corpuscular hem... 2 | 93
abnormal bone mineralization 1 | 55
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal glucose homeostasis 1 | 5
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal seminal vesicle morph... 1 | 47
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased lactate dehydrogenas... 1 | 14
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
increased blood urea nitrogen ... 1 | 44
increased circulating alkaline... 1 | 119
increased circulating triglyce... 1 | 24
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased respiratory quotient 1 | 12
small testis 1 | 37
thrombocytosis 1 | 23

Disease

Cancer 45 | 2,346
ovarian cancer 42 | 8,484
osteosarcoma 37 | 7,933
lung cancer 32 | 4,466
psoriasis 31 | 6,685
Carcinoma 29 | 2,147
glioblastoma 27 | 5,572
medulloblastoma, large-cell 26 | 6,234
Breast cancer 24 | 3,094
invasive ductal carcinoma 22 | 2,950
non-small cell lung cancer 22 | 2,798
pancreatic cancer 22 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
atypical teratoid / rhabdoid tumor 20 | 4,369
oligodendroglioma 20 | 2,849
Renal Cell Carcinoma 17 | 199
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
Mammary Neoplasms 16 | 410
breast carcinoma 16 | 1,614
interstitial cystitis 16 | 2,299
lung adenocarcinoma 16 | 2,713
malignant mesothelioma 16 | 3,162
pilocytic astrocytoma 16 | 3,086
ulcerative colitis 16 | 2,087
Lung Neoplasms 15 | 171
astrocytic glioma 15 | 2,241
diabetes mellitus 15 | 1,663
juvenile dermatomyositis 15 | 1,189
subependymal giant cell astrocytoma 15 | 2,287
ductal carcinoma in situ 14 | 1,745
Stomach Neoplasms 13 | 282
group 3 medulloblastoma 13 | 2,254
lung carcinoma 13 | 2,844
medulloblastoma 13 | 1,524
non-small cell lung carcinoma 13 | 413
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
pediatric high grade glioma 13 | 2,712
Liver carcinoma 12 | 217
Obesity 12 | 616
Prostatic Neoplasms 12 | 471
Squamous cell carcinoma 12 | 94
adrenocortical carcinoma 12 | 1,427
ovarian neoplasm 12 | 97
pituitary cancer 12 | 1,972
tuberculosis 12 | 1,557
Intellectual disability 11 | 573
Pick disease 11 | 1,893
Vascular disease 11 | 281
colon cancer 11 | 1,475
nasopharyngeal carcinoma 11 | 1,056
primary pancreatic ductal adenocarcinoma 11 | 1,271
primitive neuroectodermal tumor 11 | 3,031
Adenoma 10 | 165
Schizophrenia 10 | 501
cutaneous lupus erythematosus 10 | 1,056
dermatomyositis 10 | 933
ependymoma 10 | 2,514
Adenocarcinoma 9 | 115
Glioma 9 | 65
Heart disease 9 | 279
Kidney cancer 9 | 118
Multiple myeloma 9 | 1,327
Neoplasm Metastasis 9 | 138
Papillary thyroid carcinoma 9 | 37
acute quadriplegic myopathy 9 | 1,157
astrocytoma 9 | 1,493
Colorectal Neoplasms 8 | 217
Diarrhea 8 | 155
Neoplasm Invasiveness 8 | 127
atypical teratoid/rhabdoid tumor 8 | 1,095
cystic fibrosis 8 | 1,665
group 4 medulloblastoma 8 | 1,875
Carcinoma of thyroid 7 | 17
Exanthem 7 | 39
Neuroblastoma 7 | 78
Neurofibromatosis 7 | 37
adult high grade glioma 7 | 2,148
posterior fossa group A ependymoma 7 | 1,511
Alzheimer's disease 6 | 644
Animal Mammary Neoplasms 6 | 136
Autistic Disorder 6 | 320
Bladder Neoplasm 6 | 109
Cholangiocarcinoma 6 | 32
Colonic Neoplasms 6 | 126
Diabetes Mellitus, Non-Insulin-Dependent 6 | 157
Disease Progression 6 | 125
Endometrial cancer 6 | 25
Endometriosis 6 | 535
IGA Glomerulonephritis 6 | 454
Immune system cancer 6 | 38
Mammary Neoplasms, Experimental 6 | 150
Melanoma 6 | 261
Metabolic syndrome X 6 | 155
Neutropenia 6 | 78
Parkinson's disease 6 | 364
Rheumatoid Arthritis 6 | 1,160
Skin cancer 6 | 37
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
gastric carcinoma 6 | 832

Tissue

Blood and immune system 67 | 17,995
Cardiovascular System 67 | 17,958
Digestive Tract 67 | 18,473
Endocrine System 67 | 18,512
Female tissues 67 | 18,647
Liver and Pancreas 67 | 18,136
Male tissues 67 | 17,969
Nervous System 67 | 18,561
Urinary Tract 67 | 18,444
Respiratory system 66 | 17,484
Skin and soft tissues 66 | 18,115

Target Family

Kinase 37 | 634
Enzyme 19 | 4,146
Transporter 5 | 473
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Non-IDG 1 | 11,971

KEGG Pathway

Central carbon metabolism in c... 67 | 67
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
Pyruvate kinase PKM PKM Tchem Kinase -3.09101 1313.5 672
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.16453 144.3 98
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600
L-lactate dehydrogenase A chain LDHA Tchem Enzyme -2.99664 983.0 487
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.78634 57.0 688
Monocarboxylate transporter 4 SLC16A3 Tchem Transporter -1.28824 17.3 145
ATP-dependent 6-phosphofructokinase, platelet type PFKP Tbio Kinase -1.89344 74.7 268
Glutaminase kidney isoform, mitochondrial GLS Tchem Enzyme -2.84808 716.9 224