Development Level

Tbio 192 | 11,445
Tchem 14 | 1,598
Tclin 12 | 613
Tdark 7 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
decreased grip strength 5 | 116
decreased fasted circulating g... 4 | 65
decreased lymphocyte cell numb... 4 | 83
abnormal behavior 3 | 298
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
increased circulating triglyce... 3 | 42
increased total body fat amoun... 3 | 134
preweaning lethality, complete... 3 | 979
short tibia 3 | 97
tremors 3 | 39
abnormal bone structure 2 | 187
abnormal locomotor behavior 2 | 24
abnormal sleep behavior 2 | 70
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased pulmonary respirator... 2 | 5
decreased startle reflex 2 | 75
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
male infertility 2 | 123
small thymus 2 | 16
abnormal anxiety-related respo... 1 | 1
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal social-conspecific in... 1 | 3
abnormal tail movements 1 | 12
cataract 1 | 92
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating free fat... 1 | 31
decreased circulating serum al... 1 | 82
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased leukocyte cell numbe... 1 | 73
decreased monocyte cell number 1 | 8
decreased red blood cell distr... 1 | 41
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hemorrhage 1 | 23
hydrometra 1 | 53
hypoactivity 1 | 132
increased CD4-positive, alpha ... 1 | 4
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating glycerol... 1 | 9
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
mydriasis 1 | 6
prolonged ST segment 1 | 36
shortened PR interval 1 | 6
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Cancer 135 | 2,499
Carcinoma 126 | 11,493
psoriasis 125 | 6,694
diabetes mellitus 89 | 1,728
Hypersensitivity reaction type II disease 85 | 253
osteosarcoma 79 | 7,950
Rheumatoid arthritis 77 | 1,191
Ankylosing spondylitis 71 | 140
Behcet's disease 70 | 89
ovarian cancer 70 | 8,520
lung cancer 68 | 4,740
Arthritis 67 | 290
glioblastoma 67 | 5,792
Juvenile rheumatoid arthritis 65 | 111
Human immunodeficiency virus infectious disease 61 | 138
Acquired immunodeficiency syndrome 60 | 197
Uveitis 60 | 103
lung carcinoma 60 | 2,843
Multiple Sclerosis 58 | 540
Herpes zoster 57 | 68
interstitial cystitis 57 | 2,312
medulloblastoma, large-cell 56 | 6,241
invasive ductal carcinoma 55 | 2,951
non-small cell lung cancer 55 | 2,890
Psoriatic arthritis 53 | 86
tuberculosis 53 | 2,010
Stevens-Johnson syndrome 50 | 92
atypical teratoid / rhabdoid tumor 50 | 5,112
dermatomyositis 50 | 966
Dermatitis 47 | 157
Astrocytoma, Pilocytic 46 | 3,081
adult high grade glioma 46 | 3,801
ependymoma 45 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,989
lung adenocarcinoma 40 | 2,716
cutaneous lupus erythematosus 39 | 1,057
malignant mesothelioma 39 | 3,232
subependymal giant cell astrocytoma 39 | 2,287
Breast cancer 38 | 3,578
Synovitis 37 | 78
Kidney disease 36 | 430
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,955
ulcerative colitis 35 | 1,819
Kidney cancer 34 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
Liver disease 32 | 237
Schizophrenia 32 | 1,160
Hepatitis B 31 | 108
group 3 medulloblastoma 31 | 4,104
oligodendroglioma 29 | 2,850
Anemia 28 | 365
ductal carcinoma in situ 28 | 1,745
pituitary cancer 28 | 1,972
cystic fibrosis 27 | 1,696
breast carcinoma 26 | 1,638
Leprosy 25 | 73
Primary immunodeficiency disease 25 | 54
Skin disease 25 | 66
pancreatic cancer 25 | 2,398
primitive neuroectodermal tumor 25 | 3,035
Systemic lupus erythematosus 24 | 194
Hemochromatosis 22 | 54
colon cancer 22 | 1,478
Birdshot chorioretinopathy 21 | 23
adrenocortical carcinoma 21 | 1,428
primary Sjogren syndrome 21 | 735
Duchenne muscular dystrophy 20 | 601
sarcoidosis 20 | 370
Asthma 19 | 385
active Crohn's disease 19 | 922
astrocytic glioma 19 | 2,597
group 4 medulloblastoma 19 | 1,855
juvenile dermatomyositis 19 | 1,187
Autistic Disorder 18 | 364
Autosomal recessive predisposition 18 | 1,442
Bipolar Disorder 18 | 666
astrocytoma 18 | 1,146
primary pancreatic ductal adenocarcinoma 18 | 1,109
Berylliosis 16 | 28
Inflammatory bowel disease 16 | 151
Narcolepsy 16 | 72
esophageal adenocarcinoma 16 | 737
pediatric high grade glioma 16 | 1,064
Multiple Sclerosis, Susceptibility to 15 | 15
Pick disease 15 | 1,894
Pre-Eclampsia 15 | 68
active ulcerative colitis 15 | 764
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Liver cancer 14 | 604
Narcolepsy-cataplexy 14 | 21
Psoriasis susceptibility 1 14 | 14
head and neck cancer and chronic obstructive pulmonary disease 14 | 239
Crohn's disease 13 | 321

Tissue

Digestive Tract 136 | 17,369
Endocrine System 135 | 18,159
Female tissues 135 | 17,400
Liver and Pancreas 133 | 16,750
Skin and soft tissues 133 | 17,230
Blood and immune system 131 | 16,909
Male tissues 131 | 17,142
Respiratory system 130 | 16,393
Urinary Tract 130 | 16,678
Nervous System 126 | 16,725
Cardiovascular System 118 | 15,192

Target Family

Non-IDG 217 | 12,091
Enzyme 8 | 4,145

KEGG Pathway

Cell adhesion molecules (CAMs) 225 | 225
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Claudin-16 CLDN16 Tbio Non-IDG -1.98248 102.4 138
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Neurexin-3 NRXN3 Tbio Non-IDG -1.34072 34.8 172
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
HLA class I histocompatibility antigen, Cw-17 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952