Development Level

Tchem 14 | 1,388
Tbio 13 | 11,651
Tclin 13 | 612
Tdark 2 | 6,593

IMPC Phenotype

decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytosis 1 | 27

Disease

Carcinoma 34 | 11,493
ovarian cancer 20 | 8,520
psoriasis 20 | 6,694
medulloblastoma, large-cell 16 | 6,241
osteosarcoma 16 | 7,950
glioblastoma 15 | 5,792
lung cancer 15 | 4,740
atypical teratoid / rhabdoid tumor 14 | 5,112
diabetes mellitus 14 | 1,728
Kidney cancer 13 | 2,613
group 3 medulloblastoma 12 | 4,104
Autosomal recessive predisposition 11 | 1,442
adult high grade glioma 11 | 3,801
Breast cancer 10 | 3,578
Cancer 10 | 2,499
Epilepsy 10 | 792
lung adenocarcinoma 10 | 2,716
Atrial Fibrillation 9 | 124
Obesity 9 | 678
ependymoma 9 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
Chronic heart failure 8 | 46
Congestive heart failure 8 | 113
Poisoning by digitalis glycoside 8 | 8
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
invasive ductal carcinoma 8 | 2,951
lung carcinoma 8 | 2,843
Astrocytoma, Pilocytic 7 | 3,081
Seizures 7 | 596
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
Adenoma 6 | 167
Bipolar Disorder 6 | 666
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Hyperglycemia 6 | 137
Hypertension 6 | 396
Hypertensive disease 6 | 292
Mental and motor retardation 6 | 608
Parkinson's disease 6 | 392
Schizophrenia 6 | 1,160
Type 2 diabetes mellitus 6 | 272
juvenile dermatomyositis 6 | 1,187
tuberculosis 6 | 2,010
Breast Neoplasms 5 | 445
Diabetes mellitus type 2 5 | 69
Diarrhea 5 | 253
Endometrial cancer 5 | 311
Liver cancer 5 | 604
Mammary Neoplasms 5 | 425
Osteoporosis 5 | 363
Pick disease 5 | 1,894
Skin cancer 5 | 469
Waldenstrons macroglobulinemia 5 | 765
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
nephrosclerosis 5 | 333
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Big calvaria 4 | 147
Cerebellar Ataxia 4 | 304
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Dull intelligence 4 | 645
Failure to gain weight 4 | 365
Hypoglycemia 4 | 152
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Liver carcinoma 4 | 240
Low intelligence 4 | 645
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Metabolic acidosis 4 | 90
Microstomia 4 | 78
Orbital separation excessive 4 | 244
Pediatric failure to thrive 4 | 365
Poor school performance 4 | 645
Rheumatoid arthritis 4 | 1,191
Splenomegaly 4 | 190
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
nasopharyngeal carcinoma 4 | 1,058
pituitary cancer 4 | 1,972
mucosa-associated lymphoid tissue lymphoma 3 | 484

Tissue

Digestive Tract 40 | 17,369
Endocrine System 39 | 18,159
Liver and Pancreas 37 | 16,750
Skin and soft tissues 37 | 17,230
Blood and immune system 36 | 16,909
Female tissues 36 | 17,400
Male tissues 35 | 17,142
Nervous System 34 | 16,725
Urinary Tract 33 | 16,678
Cardiovascular System 32 | 15,192
Respiratory system 32 | 16,393

Target Family

Enzyme 14 | 4,145
Kinase 12 | 634
Transporter 12 | 473
GPCR 2 | 408
Ion Channel 1 | 344
Non-IDG 1 | 12,091

KEGG Pathway

Carbohydrate digestion and abs... 42 | 42
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Alpha-amylase 2B AMY2B Tbio Enzyme -2.04365 112.9 137
Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D Tclin Ion Channel -2.43448 273.2 215
Pancreatic alpha-amylase AMY2A Tclin Enzyme -2.93089 824.2 250
Protein ATP1B4 ATP1B4 Tdark Transporter -0.67056 4.78 35
Hexokinase-3 HK3 Tbio Kinase -1.72467 51.4 355
Sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 Tclin Transporter -1.36427 23.9 176
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.10090 13.3 226
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.25430 179.4 244
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.51919 316.4 758