Development Level

Tbio 19 | 10,625
Tdark 5 | 7,003
Tchem 2 | 1,890
Tclin 2 | 602

IMPC Term

increased circulating chloride... 2 | 43
abnormal behavior 1 | 226
abnormal body wall morphology 1 | 7
abnormal embryo size 1 | 112
abnormal retinal inner nuclear... 1 | 5
decreased prepulse inhibition 1 | 52
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 93
increased vertical activity 1 | 18
male infertility 1 | 62
preweaning lethality, complete... 1 | 633

Disease

pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
ovarian cancer 11 | 8,484
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
ulcerative colitis 10 | 2,087
atypical teratoid / rhabdoid tumor 9 | 4,369
interstitial cystitis 9 | 2,299
medulloblastoma, large-cell 9 | 6,234
oligodendroglioma 9 | 2,849
psoriasis 9 | 6,685
colon cancer 8 | 1,475
glioblastoma 8 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
osteosarcoma 8 | 7,933
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
lung carcinoma 7 | 2,844
Pick disease 6 | 1,893
ductal carcinoma in situ 6 | 1,745
invasive ductal carcinoma 6 | 2,950
malignant mesothelioma 6 | 3,162
primitive neuroectodermal tumor 6 | 3,031
Epilepsy 5 | 346
adrenocortical carcinoma 5 | 1,427
astrocytoma 5 | 1,493
ependymoma 5 | 2,514
lung cancer 5 | 4,466
nephrosclerosis 5 | 329
pediatric high grade glioma 5 | 2,712
Hypoglycemia 4 | 81
Succinic semialdehyde dehydrogenase deficiency 4 | 16
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 918
astrocytic glioma 4 | 2,241
non-small cell lung cancer 4 | 2,798
pilocytic astrocytoma 4 | 3,086
Multiple myeloma 3 | 1,327
Obesity 3 | 616
Schizophrenia 3 | 501
Seizures 3 | 95
adult high grade glioma 3 | 2,148
cystic fibrosis 3 | 1,665
diabetes mellitus 3 | 1,663
gastric carcinoma 3 | 832
group 4 medulloblastoma 3 | 1,875
lung adenocarcinoma 3 | 2,713
sonic hedgehog group medulloblastoma 3 | 1,482
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 644
Autistic Disorder 2 | 320
Breast cancer 2 | 3,094
Cerebellar Ataxia 2 | 72
Cocaine-Related Disorders 2 | 88
Epilepsy characterized by intractable complex partial seizures 2 | 28
Hydrolethalus syndrome 2 | 128
Hyperinsulinemic hypoglycemia 2 | 17
Hyperinsulinism 2 | 63
Intellectual disability 2 | 573
L-2-hydroxyglutaric aciduria 2 | 7
Maple syrup urine disease 2 | 25
Myocardial Ischemia 2 | 169
Reye syndrome 2 | 11
Stiff-Person syndrome 2 | 11
beta-ketothiolase deficiency 2 | 13
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
group 3 medulloblastoma 2 | 2,254
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
non primary Sjogren syndrome sicca 2 | 840
pancreatic cancer 2 | 2,300
posterior fossa group A ependymoma 2 | 1,511
posterior fossa group B ependymoma 2 | 1,530
2-hydroxyglutaric aciduria 1 | 5
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency 1 | 1
3-methylglutaconic aciduria 1 | 29
Bipolar Disorder 1 | 266
Cardiomyopathy 1 | 110
Cholestasis 1 | 93
Chronic Lymphocytic Leukemia 1 | 242
Cleft palate 1 | 125
Colitis 1 | 46
Colonic Neoplasms 1 | 126
Degenerative polyarthritis 1 | 93
Disseminated intravascular coagulation 1 | 32
Dyskinesia, Drug-Induced 1 | 15
Gastroesophageal reflux disease 1 | 37
Gaucher disease type 1 1 | 171
Gonorrhea 1 | 14
Gout 1 | 93
Hepatic vein thrombosis 1 | 8
Lactic acidosis 1 | 42
Lung Neoplasms 1 | 171
Neurodegenerative disease 1 | 383
Osteoporosis 1 | 257
Parkinson's disease 1 | 364
Placental abruption 1 | 15
Substance-Related Disorders 1 | 114
Zellweger Syndrome 1 | 38
atypical teratoid/rhabdoid tumor 1 | 1,095
facioscapulohumeral dystrophy 1 | 286

Tissue

Blood and immune system 28 | 17,995
Cardiovascular System 28 | 17,958
Digestive Tract 28 | 18,473
Endocrine System 28 | 18,512
Female tissues 28 | 18,647
Liver and Pancreas 28 | 18,136
Nervous System 28 | 18,561
Respiratory system 28 | 17,484
Skin and soft tissues 28 | 18,115
Urinary Tract 28 | 18,444
Male tissues 27 | 17,969

Target Family

Enzyme 26 | 4,146
Non-IDG 2 | 11,971

KEGG Pathway

Butanoate metabolism 28 | 28
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

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