Development Level

Tchem 18 | 1,598
Tbio 13 | 11,445
Tclin 11 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal lens morphology 3 | 81
cataract 3 | 92
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal lung morphology 2 | 26
decreased circulating insulin ... 2 | 76
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal liver morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased circulating aspartat... 1 | 34
decreased circulating magnesiu... 1 | 13
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating glucose ... 1 | 24
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality 1 | 28
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Cancer 37 | 2,499
Carcinoma 33 | 11,493
ovarian cancer 30 | 8,520
glioblastoma 28 | 5,792
lung cancer 28 | 4,740
atypical teratoid / rhabdoid tumor 25 | 5,112
osteosarcoma 25 | 7,950
Breast cancer 24 | 3,578
psoriasis 23 | 6,694
malignant mesothelioma 22 | 3,232
Breast Neoplasms 20 | 445
Mammary Neoplasms 20 | 425
medulloblastoma, large-cell 20 | 6,241
Stomach Neoplasms 19 | 300
Lung Neoplasms 17 | 232
pancreatic cancer 17 | 2,398
Kidney cancer 16 | 2,613
Neoplasm Metastasis 16 | 168
Carcinoma, Hepatocellular 15 | 228
Liver carcinoma 15 | 240
ependymoma 15 | 4,679
Bladder Neoplasm 14 | 112
Carcinoma, Non-Small-Cell Lung 14 | 107
Prostatic Neoplasms 14 | 495
Urinary Bladder Neoplasms 14 | 114
non-small cell lung carcinoma 14 | 317
oligodendroglioma 14 | 2,850
Adenoma 13 | 167
Astrocytoma, Pilocytic 13 | 3,081
Carcinoma, Squamous Cell 13 | 110
Colorectal Neoplasms 13 | 243
Melanoma 13 | 711
Squamous cell carcinoma 13 | 129
Vascular disease 13 | 319
adult high grade glioma 13 | 3,801
diabetes mellitus 13 | 1,728
group 3 medulloblastoma 13 | 4,104
interstitial cystitis 13 | 2,312
ulcerative colitis 13 | 1,819
Adenocarcinoma 12 | 122
Colonic Neoplasms 12 | 142
Short stature 12 | 531
Stomach cancer 12 | 30
astrocytic glioma 12 | 2,597
primitive neuroectodermal tumor 12 | 3,035
Autosomal recessive predisposition 11 | 1,442
Endometriosis 11 | 540
Neoplasm Invasiveness 11 | 161
Renal Cell Carcinoma 11 | 214
breast carcinoma 11 | 1,638
cystic fibrosis 11 | 1,696
ductal carcinoma in situ 11 | 1,745
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
nasopharyngeal carcinoma 11 | 1,058
subependymal giant cell astrocytoma 11 | 2,287
Blepharoptosis 10 | 231
Cell Transformation, Neoplastic 10 | 97
Heart disease 10 | 306
Immune system cancer 10 | 140
Kidney disease 10 | 430
Lymphoid leukemia 10 | 160
Neoplasms, Experimental 10 | 40
Neoplastic Cell Transformation 10 | 89
Orbital separation excessive 10 | 244
Pancreatic Neoplasm 10 | 85
Pancreatic Neoplasms 10 | 85
non-small cell lung cancer 10 | 2,890
Dull intelligence 9 | 645
Intellectual disability 9 | 1,016
Liver Neoplasms, Experimental 9 | 59
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Multiple myeloma 9 | 1,332
Muscle hypotonia 9 | 571
Papilloma 9 | 44
Poor school performance 9 | 645
Schizophrenia 9 | 1,160
Upper respiratory tract disease 9 | 15
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
tuberculosis 9 | 2,010
Arthritis 8 | 290
Byzanthine arch palate 8 | 194
Cognitive delay 8 | 608
Hypoplastic mandible condyle 8 | 275
Liver neoplasms 8 | 130
Mental and motor retardation 8 | 608
Rheumatoid arthritis 8 | 1,191
Skin cancer 8 | 469
Strabismus 8 | 270
acute quadriplegic myopathy 8 | 1,158
adrenocortical carcinoma 8 | 1,428
colon cancer 8 | 1,478
hepatocellular carcinoma 8 | 547
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
juvenile dermatomyositis 8 | 1,187
lung carcinoma 8 | 2,843
pituitary cancer 8 | 1,972
primary pancreatic ductal adenocarcinoma 8 | 1,109

Tissue

Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Cardiovascular System 39 | 15,192

Target Family

Kinase 16 | 634
Non-IDG 11 | 12,091
Enzyme 10 | 4,145
Transcription Factor 5 | 1,400

KEGG Pathway

Bladder cancer 42 | 42
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Death-associated protein kinase 2 DAPK2 Tchem Kinase -1.39206 28.7 440
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Death-associated protein kinase 3 DAPK3 Tchem Kinase -1.64668 50.7 291
Fibroblast growth factor receptor 3 FGFR3 Tclin Kinase -3.00731 1050.1 479
Transcription factor E2F2 E2F2 Tbio Transcription Factor -2.10245 108.0 267
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150
Cadherin-1 CDH1 Tbio Non-IDG -3.85201 6324.3 1880