Development Level

Tbio 30 | 11,445
Tchem 25 | 1,598
Tclin 17 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

increased startle reflex 8 | 112
increased circulating HDL chol... 6 | 80
abnormal behavior 5 | 298
increased circulating choleste... 5 | 66
abnormal bone structure 4 | 187
increased heart weight 4 | 62
decreased mean corpuscular vol... 3 | 79
hyperactivity 3 | 148
decreased body weight 2 | 161
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
enlarged heart 1 | 210
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased IgA level 1 | 1
increased body weight 1 | 25
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased circulating unsatura... 1 | 1
increased kidney weight 1 | 6
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Carcinoma 62 | 11,493
lung cancer 30 | 4,740
ovarian cancer 30 | 8,520
Cancer 25 | 2,499
Kidney cancer 25 | 2,613
medulloblastoma, large-cell 24 | 6,241
osteosarcoma 24 | 7,950
Cholestasis 23 | 155
glioblastoma 23 | 5,792
psoriasis 23 | 6,694
atypical teratoid / rhabdoid tumor 21 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
lung carcinoma 20 | 2,843
pancreatic cancer 20 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
Autosomal recessive predisposition 17 | 1,442
adult high grade glioma 17 | 3,801
ependymoma 17 | 4,679
lung adenocarcinoma 17 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
interstitial cystitis 16 | 2,312
invasive ductal carcinoma 16 | 2,951
malignant mesothelioma 16 | 3,232
non-small cell lung cancer 16 | 2,890
Astrocytoma, Pilocytic 14 | 3,081
Breast cancer 14 | 3,578
Obesity 14 | 678
group 3 medulloblastoma 14 | 4,104
oligodendroglioma 14 | 2,850
pituitary cancer 14 | 1,972
primitive neuroectodermal tumor 14 | 3,035
diabetes mellitus 13 | 1,728
Epilepsy 12 | 792
Liver disease 12 | 237
astrocytic glioma 12 | 2,597
Liver Cirrhosis, Experimental 11 | 769
Rheumatoid arthritis 11 | 1,191
active Crohn's disease 11 | 922
active ulcerative colitis 11 | 764
ductal carcinoma in situ 11 | 1,745
ulcerative colitis 11 | 1,819
Hypertension 10 | 396
cystic fibrosis 10 | 1,696
group 4 medulloblastoma 10 | 1,855
Atrial Fibrillation 9 | 124
Bipolar Disorder 9 | 666
Diarrhea 9 | 253
Liver cancer 9 | 604
Liver carcinoma 9 | 240
subependymal giant cell astrocytoma 9 | 2,287
Carcinoma, Hepatocellular 8 | 228
Chronic heart failure 8 | 46
Colorectal Neoplasms 8 | 243
Congestive heart failure 8 | 113
Depressive disorder 8 | 409
Failure to gain weight 8 | 365
Hypertensive disease 8 | 292
Kidney disease 8 | 430
Pediatric failure to thrive 8 | 365
Pick disease 8 | 1,894
Poisoning by digitalis glycoside 8 | 8
colon cancer 8 | 1,478
Adenoma 7 | 167
Biliary cirrhosis 7 | 45
Bilirubin metabolic disorder 7 | 41
Coronary artery disease 7 | 268
Cushing's syndrome 7 | 48
Prostatic Neoplasms 7 | 495
astrocytoma 7 | 1,146
mucosa-associated lymphoid tissue lymphoma 7 | 484
tuberculosis 7 | 2,010
Atherosclerosis 6 | 291
Carney complex 6 | 25
Chemical and Drug Induced Liver Injury 6 | 195
Cholelithiasis 6 | 33
Down syndrome 6 | 499
Duchenne muscular dystrophy 6 | 601
Fatty liver disease 6 | 103
Icterus 6 | 82
Lipid metabolism disorder 6 | 114
Liver Cirrhosis, Biliary 6 | 33
Mental Depression 6 | 333
Metabolic acidosis 6 | 90
Osteoporosis 6 | 363
Schizophrenia 6 | 1,160
Substance Withdrawal Syndrome 6 | 55
adrenocortical carcinoma 6 | 1,428
cutaneous lupus erythematosus 6 | 1,057
hepatocellular carcinoma 6 | 547
primary pancreatic ductal adenocarcinoma 6 | 1,109
Arthritis, Rheumatoid 5 | 174
Hepatomegaly 5 | 285
Polycystic ovary syndrome 5 | 360
aldosterone-producing adenoma 5 | 665
breast carcinoma 5 | 1,638
chronic rhinosinusitis 5 | 512
gastric carcinoma 5 | 807
nephrosclerosis 5 | 333
pancreatic carcinoma 5 | 562

Tissue

Endocrine System 69 | 18,159
Liver and Pancreas 69 | 16,750
Digestive Tract 68 | 17,369
Urinary Tract 66 | 16,678
Skin and soft tissues 65 | 17,230
Female tissues 64 | 17,400
Male tissues 64 | 17,142
Blood and immune system 63 | 16,909
Nervous System 61 | 16,725
Respiratory system 57 | 16,393
Cardiovascular System 54 | 15,192

Target Family

Transporter 36 | 473
Enzyme 19 | 4,145
Non-IDG 10 | 12,091
Kinase 3 | 634
Nuclear Receptor 3 | 48
Ion Channel 2 | 344
GPCR 1 | 408

KEGG Pathway

Bile secretion 74 | 74
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Electrogenic sodium bicarbonate cotransporter 1 SLC4A4 Tbio Transporter -2.63743 436.2 124
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Solute carrier family 22 member 7 SLC22A7 Tbio Transporter -2.14673 131.0 76
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Sodium/bile acid cotransporter SLC10A1 Tchem Transporter -2.69150 476.1 163
Organic solute transporter subunit beta SLC51B Tbio Transporter -1.41741 22.6 42
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Bile acyl-CoA synthetase SLC27A5 Tbio Transporter -2.32176 196.8 181
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64