Development Level

Tbio 20 | 11,445
Tchem 7 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal retinal inner nuclear... 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased total retina thickne... 1 | 17
increased circulating alkaline... 1 | 122
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 19 | 11,493
Cancer 17 | 2,499
group 3 medulloblastoma 17 | 4,104
osteosarcoma 16 | 7,950
ovarian cancer 15 | 8,520
psoriasis 14 | 6,694
lung cancer 13 | 4,740
malignant mesothelioma 13 | 3,232
medulloblastoma, large-cell 13 | 6,241
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
primitive neuroectodermal tumor 9 | 3,035
Breast cancer 8 | 3,578
non-small cell lung cancer 8 | 2,890
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
Colorectal Neoplasms 6 | 243
Malignant tumor of ovary 6 | 25
Waldenstrons macroglobulinemia 6 | 765
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
oligodendroglioma 6 | 2,850
Autosomal recessive predisposition 5 | 1,442
Multiple myeloma 5 | 1,332
Cockayne syndrome 4 | 60
Colonic Neoplasms 4 | 142
Kidney cancer 4 | 2,613
Lynch syndrome 4 | 35
Malignant tumor of peritoneum 4 | 6
Neurodegenerative disease 4 | 414
Prostatic Neoplasms 4 | 495
Xeroderma pigmentosum group G 4 | 16
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Bloom syndrome 3 | 29
Carcinoma in situ of fallopian tube 3 | 4
Epithelial tumor of ovary 3 | 3
Familial adenomatous polyposis 3 | 32
Heart disease 3 | 306
Malignant epithelial tumor of ovary 3 | 5
Stomach Neoplasms 3 | 300
Xeroderma pigmentosum group D 3 | 33
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
Acute lymphoid leukemia 2 | 25
Acute myeloid leukemia, disease 2 | 30
Adenocarcinoma 2 | 122
Adenocarcinoma of lung 2 | 142
Adenoma 2 | 167
Adenomatous Polyposis Coli 2 | 16
Alzheimer's disease 2 | 658
Arthritis 2 | 290
Arts syndrome 2 | 26
Atherosclerosis 2 | 291
Bladder Neoplasm 2 | 112
Brain Injuries 2 | 65
Cerebrovascular disease 2 | 238
Colorectal adenoma 2 | 15
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Esophageal Squamous Cell Carcinoma 2 | 77
Heart Diseases 2 | 43
Immunologic Deficiency Syndromes 2 | 113
Inflammation 2 | 120
Insulin Resistance 2 | 72
Kyphosis deformity of spine 2 | 114
Lipodystrophy 2 | 40
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Melanoma 2 | 711
Meningeal Leukemia 2 | 7
Metastatic Breast Carcinoma 2 | 21
Myocardial Infarction 2 | 151
Nerve Degeneration 2 | 121
Osteoporosis 2 | 363
Pancreatitis 2 | 123
Pick disease 2 | 1,894
Pulmonary Fibrosis 2 | 106
Short stature 2 | 531
Squamous cell carcinoma of esophagus 2 | 77
Urinary Bladder Neoplasms 2 | 114
Werner syndrome 2 | 29
Xeroderma pigmentosum 2 | 43
Xeroderma pigmentosum group F 2 | 22
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
gastric carcinoma 2 | 807
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Cardiovascular System 32 | 15,192

Target Family

Enzyme 29 | 4,145
Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400

KEGG Pathway

Base excision repair 33 | 33
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Poly [ADP-ribose] polymerase 4 PARP4 Tchem Enzyme -1.45503 26.0 123
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.86910 750.8 255
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
DNA polymerase delta subunit 4 POLD4 Tbio Enzyme -0.84887 7.32 24
Single-strand selective monofunctional uracil DNA glycosylase SMUG1 Tbio Enzyme -4.31831 20587.4 199
Uracil-DNA glycosylase UNG Tbio Enzyme -2.82957 680.9 352
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.26147 1834.9 293
Methyl-CpG-binding domain protein 4 MBD4 Tbio Transcription Factor -1.99625 98.6 183
Endonuclease 8-like 2 NEIL2 Tbio Enzyme -1.74921 49.0 107