Development Level

Tbio 38 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 3 | 278
abnormal retina morphology 2 | 71
increased circulating potassiu... 2 | 29
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
hydrometra 1 | 53
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 26 | 11,493
osteosarcoma 23 | 7,950
ovarian cancer 19 | 8,520
lung cancer 16 | 4,740
Photosensitive trichothiodystrophy 11 | 30
Cockayne syndrome 10 | 60
psoriasis 10 | 6,694
Xeroderma pigmentosum group B 9 | 20
Intellectual disability 8 | 1,016
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
Kidney cancer 7 | 2,613
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
Cancer 6 | 2,499
Pick disease 6 | 1,894
Xeroderma pigmentosum group D 6 | 33
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
oligodendroglioma 6 | 2,850
Dull intelligence 5 | 645
Epidermodysplasia verruciformis 5 | 21
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Muscle Spasticity 5 | 195
Poor school performance 5 | 645
Small head 5 | 374
Xeroderma pigmentosum 5 | 43
astrocytic glioma 5 | 2,597
malignant mesothelioma 5 | 3,232
primitive neuroectodermal tumor 5 | 3,035
Arthralgia 4 | 90
Autosomal recessive predisposition 4 | 1,442
Hyperreflexia 4 | 209
Multiple myeloma 4 | 1,332
Sensorineural Hearing Loss (disorder) 4 | 284
Short stature 4 | 531
Strabismus 4 | 270
Trichothiodystrophy Syndromes 4 | 6
Xeroderma pigmentosum group G 4 | 16
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
Astrocytoma, Pilocytic 3 | 3,081
Broad flat nasal bridge 3 | 236
Cerebellar Dysmetria 3 | 56
Depressive disorder 3 | 409
Everted lower lip vermilion 3 | 54
Gaucher disease type 1 3 | 180
Hypoplastic mandible condyle 3 | 275
Joint stiffness 3 | 84
Low Vision 3 | 174
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Micrognathism 3 | 275
Muscle hypotonia 3 | 571
Nasal bridge wide 3 | 236
Protruding lower lip 3 | 54
Tremor 3 | 113
Trichothiodystrophy 1, photosensitive 3 | 4
Visual Impairment 3 | 174
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
pituitary cancer 3 | 1,972
Abnormality of the fingernails 2 | 51
Basal cell nevi 2 | 23
Bunion 2 | 26
Colon diverticulum anatomic structure 2 | 15
Congenital anomaly of neck 2 | 19
Deformity of neck 2 | 19
Dental abnormalities 2 | 60
Diverticular disease of colon 2 | 15
Dysgraphia 2 | 20
Erythema 2 | 58
Flatfoot 2 | 73
Flushing 2 | 60
Gait imbalance 2 | 17
Hallux Valgus 2 | 26
High-grade hypermetropia 2 | 24
Hoarseness 2 | 31
Hypercalcemia 2 | 59
Hypercalciuria 2 | 27
Hyperkeratosis 2 | 50
Hyperpigmented macules 2 | 42
Hypertension, Renovascular 2 | 10
Kyphosis deformity of spine 2 | 114
Lordosis 2 | 54
Malformation of the neck 2 | 19
Mitral valve insufficiency 2 | 49
Mixed connective tissue disease 2 | 16
Papilloma 2 | 44
Progressive mental retardation 2 | 37
Pulmonary Stenosis 2 | 45
Sloping shoulders 2 | 21
Supravalvular aortic stenosis 2 | 12
Tooth Abnormalities 2 | 69
hypopigmented skin patch 2 | 59
obsessive-compulsive disorder 2 | 61

Tissue

Endocrine System 44 | 18,159
Blood and immune system 43 | 16,909
Digestive Tract 43 | 17,369
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678
Nervous System 42 | 16,725
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 33 | 12,091
Enzyme 5 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634
Transcription Factor 2 | 1,400

KEGG Pathway

Basal transcription factors 44 | 44
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
General transcription factor II-I repeat domain-containing protein 1 GTF2IRD1 Tbio Transcription Factor -1.74692 0.00000 281
Transcription initiation factor TFIID subunit 9B TAF9B Tbio Non-IDG -1.38372 23.5 105
TFIIA-alpha and beta-like factor GTF2A1L Tbio Non-IDG -0.66901 3.86 222
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -1.32757 20.2 148
Transcription initiation factor TFIID subunit 4 TAF4 Tbio Non-IDG -1.42226 27.6 64
Transcription initiation factor TFIID subunit 4B TAF4B Tbio Non-IDG 0.60 0.22 80
TATA box-binding protein-like protein 2 TBPL2 Tbio Non-IDG -1.52558 32.3 102
Transcription initiation factor TFIID subunit 5 TAF5 Tbio Non-IDG -1.08338 9.03 81
Transcription initiation factor TFIID subunit 7 TAF7 Tbio Non-IDG -1.16026 13.4 138
Transcription initiation factor TFIID subunit 11 TAF11 Tbio Non-IDG -0.83855 7.10 194