Development Level

Tbio 28 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 2 | 298
decreased blood urea nitrogen ... 2 | 51
increased mean corpuscular hem... 2 | 96
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating serum al... 1 | 22
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 20 | 11,493
ovarian cancer 19 | 8,520
osteosarcoma 18 | 7,950
psoriasis 14 | 6,694
medulloblastoma, large-cell 13 | 6,241
Cancer 9 | 2,499
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
subependymal giant cell astrocytoma 8 | 2,287
Kidney cancer 7 | 2,613
lung cancer 7 | 4,740
adult high grade glioma 6 | 3,801
Breast cancer 5 | 3,578
astrocytic glioma 5 | 2,597
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
Multiple myeloma 4 | 1,332
Schizophrenia 4 | 1,160
group 4 medulloblastoma 4 | 1,855
tuberculosis 4 | 2,010
Anemia 3 | 365
Granulomatous amebic encephalitis 3 | 8
Lung Neoplasms 3 | 232
Ovarian Neoplasms 3 | 102
Parkinson's disease 3 | 392
Vascular disease 3 | 319
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
gastric cancer 3 | 459
pituitary cancer 3 | 1,972
tuberculosis and treatment for 6 months 3 | 409
Autistic Disorder 2 | 364
Carcinoma, Hepatocellular 2 | 228
Centronuclear myopathy 2 | 27
Connective tissue disease 2 | 62
Globe disease 2 | 67
Intellectual disability 2 | 1,016
Lethargy 2 | 77
Liver carcinoma 2 | 240
Lymphopenia 2 | 67
Malaria 2 | 160
Necrosis 2 | 53
Neurodegenerative disease 2 | 414
Pick disease 2 | 1,894
Renal Cell Carcinoma 2 | 214
Toxic encephalopathy 2 | 141
Vici syndrome 2 | 14
Waldenstrons macroglobulinemia 2 | 765
Weight Loss 2 | 24
Weight decreased 2 | 103
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
posterior fossa group A ependymoma 2 | 468
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
Adenocarcinoma 1 | 122
Breast Neoplasms 1 | 445
Capuchin ears 1 | 17
Carcinoma, Renal Cell 1 | 124
Chemical and Drug Induced Liver Injury 1 | 195
Common variable immunodeficiency 1 | 101
Crohn Disease 1 | 45
Cupped ears (finding) 1 | 17
Downward slant of palpebral fissure 1 | 158
FG syndrome 1 | 16
Hypertrophy of breast 1 | 17
Hypertrophy, Left Ventricular 1 | 24
Left Ventricular Hypertrophy 1 | 47
Mammary Neoplasms 1 | 425
Mucopolysaccharidosis III 1 | 7
Mucositis 1 | 29
Muscular atrophy 1 | 71
Myeloproliferative disease 1 | 16
Myocardial Infarction 1 | 151
Narcolepsy 1 | 72
Neurodegeneration with brain iron accumulation 5 1 | 9
Neuronal ceroid lipofuscinosis 8 northern epilepsy variant 1 | 6
Nicotine dependence 1 | 54
REM sleep behavior disorder 1 | 14
Retrognathia 1 | 54
Seborrheic keratosis 1 | 8
Thrombocytopenia 1 | 197
Uterine Cervical Neoplasm 1 | 25
Uterine Cervical Neoplasms 1 | 26
Visual epilepsy 1 | 4
X- linked recessive 1 | 110
inflammatory breast cancer 1 | 286
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 22 | 12,091
Enzyme 6 | 4,145
Kinase 4 | 634

KEGG Pathway

Autophagy - other 32 | 32
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beclin-2 BECN2 Tbio Non-IDG 0.00000 87
Cysteine protease ATG4A ATG4A Tbio Enzyme -1.07944 9.29 261
Cysteine protease ATG4B ATG4B Tbio Enzyme -1.79492 58.3 416
Gamma-aminobutyric acid receptor-associated protein-like 1 GABARAPL1 Tbio Non-IDG -2.39692 232.7 211
Serine/threonine-protein kinase ULK2 ULK2 Tchem Kinase -1.20211 12.1 391
Autophagy-related protein 2 homolog A ATG2A Tbio Non-IDG -0.69230 5.62 80
Autophagy-related protein 9B ATG9B Tbio Non-IDG 0.00000 142
Autophagy-related protein 16-1 ATG16L1 Tbio Non-IDG -2.26343 183.4 600
Cysteine protease ATG4D ATG4D Tbio Enzyme -0.65555 4.93 376
Immunoglobulin-binding protein 1 IGBP1 Tbio Non-IDG -2.37181 215.8 162