Development Level

Tbio 109 | 10,625
Tchem 11 | 1,890
Tclin 6 | 602
Tdark 4 | 7,003

IMPC Term

decreased T cell number 1 | 31
decreased heart weight 1 | 44
decreased monocyte cell number 1 | 28
increased CD4-positive, alpha ... 1 | 15
increased leukocyte cell numbe... 1 | 37

Disease

Cancer 88 | 2,346
diabetes mellitus 78 | 1,663
Hypersensitivity reaction type II disease 75 | 235
Ankylosing spondylitis 71 | 138
psoriasis 67 | 6,685
Juvenile rheumatoid arthritis 62 | 104
Acquired immunodeficiency syndrome 61 | 164
Arthritis 61 | 248
Uveitis 61 | 103
Behcet's disease 56 | 74
Psoriatic arthritis 53 | 83
Rheumatoid Arthritis 53 | 1,160
Multiple Sclerosis 44 | 498
Stevens-Johnson syndrome 39 | 78
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Takayasu's arteritis 35 | 52
Hepatitis B 33 | 103
Anemia 28 | 252
Kidney disease 28 | 396
Leprosy 28 | 77
Liver disease 28 | 219
Primary immunodeficiency disease 26 | 52
Skin disease 23 | 65
Hemochromatosis 22 | 55
Human immunodeficiency virus infectious disease 21 | 92
lung cancer 20 | 4,466
lung carcinoma 20 | 2,844
glioblastoma 16 | 5,572
ovarian cancer 16 | 8,484
Asthma 15 | 349
osteosarcoma 15 | 7,933
pre-eclampsia 15 | 67
tuberculosis 15 | 1,557
cutaneous lupus erythematosus 14 | 1,056
interstitial cystitis 14 | 2,299
pilocytic astrocytoma 13 | 3,086
primary Sjogren syndrome 13 | 789
subependymal giant cell astrocytoma 13 | 2,287
Dermatitis 11 | 107
Influenza 11 | 142
invasive ductal carcinoma 11 | 2,950
non-small cell lung cancer 11 | 2,798
Type 1 diabetes mellitus 10 | 101
active Crohn's disease 10 | 918
breast carcinoma 10 | 1,614
dermatomyositis 10 | 933
Allergic hypersensitivity disease 9 | 123
Celiac disease 9 | 112
Graves' disease 9 | 25
astrocytoma 9 | 1,493
juvenile dermatomyositis 9 | 1,189
posterior fossa group A ependymoma 9 | 1,511
sarcoidosis 9 | 358
Autistic Disorder 8 | 320
Autoimmune thyroiditis 8 | 24
Duchenne muscular dystrophy 8 | 602
Hepatitis 8 | 61
Hypersensitivity 8 | 63
Inflammatory bowel disease 8 | 142
Tetanus 8 | 66
adult high grade glioma 8 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
ulcerative colitis 8 | 2,087
Hepatitis B, Chronic 7 | 15
Hepatitis C 7 | 90
Leishmaniasis 7 | 49
Multiple myeloma 7 | 1,327
Vasculitis 7 | 64
active ulcerative colitis 7 | 477
head and neck cancer and chronic obstructive pulmonary disease 7 | 237
malignant mesothelioma 7 | 3,162
Addison's disease 6 | 29
Adult T-Cell Lymphoma/Leukemia 6 | 30
Diabetes Mellitus, Insulin-Dependent 6 | 76
Diarrhea 6 | 155
Drug allergy 6 | 36
Drug-Induced Liver Injury 6 | 118
Eosinophilia 6 | 65
Hypothyroidism 6 | 89
Leukopenia 6 | 42
Lupus Erythematosus, Systemic 6 | 73
Narcolepsy 6 | 58
Thrombocytopenia 6 | 105
Thyrotoxicosis 6 | 38
colon cancer 6 | 1,475
esophageal adenocarcinoma 6 | 737
limb girdle muscular dystrophy 2I 6 | 56
Encephalitis 5 | 54
HIV Infections 5 | 100
Liver Cirrhosis 5 | 101
Lung disease 5 | 132
Malaria 5 | 140
Melanoma 5 | 261
Schistosomiasis 5 | 38
Urticaria 5 | 53
adrenocortical carcinoma 5 | 1,427
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
medulloblastoma, large-cell 5 | 6,234
pituitary cancer 5 | 1,972

Tissue

Nervous System 58 | 18,561
Female tissues 57 | 18,647
Digestive Tract 56 | 18,473
Urinary Tract 56 | 18,444
Blood and immune system 52 | 17,995
Endocrine System 52 | 18,512
Cardiovascular System 50 | 17,958
Liver and Pancreas 49 | 18,136
Respiratory system 49 | 17,484
Male tissues 47 | 17,969
Skin and soft tissues 44 | 18,115

Target Family

Non-IDG 127 | 11,971
Enzyme 2 | 4,146
GPCR 1 | 406

KEGG Pathway

Autoimmune thyroid disease 130 | 130
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

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