Development Level

Tbio 115 | 11,651
Tchem 6 | 1,388
Tclin 6 | 612
Tdark 3 | 6,593

IMPC Phenotype

decreased T cell number 1 | 15
decreased heart weight 1 | 27
decreased monocyte cell number 1 | 8
decreased vertical activity 1 | 208
increased CD4-positive, alpha ... 1 | 4
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32

Disease

Cancer 90 | 2,499
diabetes mellitus 80 | 1,728
Hypersensitivity reaction type II disease 75 | 253
Ankylosing spondylitis 71 | 140
Behcet's disease 70 | 89
psoriasis 69 | 6,694
Juvenile rheumatoid arthritis 65 | 111
Rheumatoid arthritis 65 | 1,191
Arthritis 63 | 290
Uveitis 62 | 103
Acquired immunodeficiency syndrome 61 | 197
Herpes zoster 58 | 68
Human immunodeficiency virus infectious disease 57 | 138
Psoriatic arthritis 53 | 86
Stevens-Johnson syndrome 52 | 92
Carcinoma 49 | 11,493
Dermatitis 45 | 157
Multiple Sclerosis 42 | 540
dermatomyositis 41 | 966
Behcet's syndrome 37 | 50
tuberculosis 37 | 2,010
Hepatitis B 36 | 108
Nephritis 36 | 51
Synovitis 36 | 78
Congenital adrenal hyperplasia 35 | 73
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
Anemia 30 | 365
Kidney disease 28 | 430
Leprosy 28 | 73
Liver disease 28 | 237
Primary immunodeficiency disease 28 | 54
Skin disease 23 | 66
Hemochromatosis 22 | 54
Birdshot chorioretinopathy 21 | 23
lung cancer 21 | 4,740
lung carcinoma 20 | 2,843
sarcoidosis 20 | 370
Systemic lupus erythematosus 18 | 194
Berylliosis 16 | 28
Narcolepsy 16 | 72
glioblastoma 16 | 5,792
ovarian cancer 16 | 8,520
Human immunodeficiency virus type 1, susceptibility to 15 | 26
Pre-Eclampsia 15 | 68
osteosarcoma 15 | 7,950
Asthma 14 | 385
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
Psoriasis susceptibility 1 14 | 14
cutaneous lupus erythematosus 14 | 1,057
interstitial cystitis 14 | 2,312
Astrocytoma, Pilocytic 13 | 3,081
Diffuse cutaneous systemic sclerosis 13 | 17
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
Schizophrenia 13 | 1,160
follicular lymphoma 13 | 20
limited scleroderma 13 | 19
subependymal giant cell astrocytoma 13 | 2,287
Vasculitis 12 | 80
Fatigue 11 | 182
Influenza 11 | 142
invasive ductal carcinoma 11 | 2,951
non-small cell lung cancer 11 | 2,890
Autoimmune Diseases 10 | 67
Type 1 diabetes mellitus 10 | 109
active Crohn's disease 10 | 922
adult high grade glioma 10 | 3,801
breast carcinoma 10 | 1,638
primary Sjogren syndrome 10 | 735
Allergic hypersensitivity disease 9 | 126
Celiac disease 9 | 116
Graves' disease 9 | 24
Inflammatory bowel disease 9 | 151
Weight decreased 9 | 103
juvenile dermatomyositis 9 | 1,187
Arthritis, Rheumatoid 8 | 174
Autistic Disorder 8 | 364
Autoimmune thyroiditis 8 | 27
Diarrhea 8 | 253
Duchenne muscular dystrophy 8 | 601
Fever 8 | 138
Hepatitis 8 | 67
Hypersensitivity 8 | 63
Leukopenia 8 | 72
Tetanus 8 | 68
Thrombocytopenia 8 | 197
Urticaria 8 | 67
active ulcerative colitis 8 | 764
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
malignant mesothelioma 8 | 3,232
ulcerative colitis 8 | 1,819
Bipolar Disorder 7 | 666
Leishmaniasis 7 | 47
Multiple myeloma 7 | 1,332
astrocytoma 7 | 1,146
head and neck cancer and chronic obstructive pulmonary disease 7 | 239

Tissue

Blood and immune system 36 | 16,909
Liver and Pancreas 35 | 16,750
Digestive Tract 34 | 17,369
Female tissues 34 | 17,400
Male tissues 34 | 17,142
Skin and soft tissues 34 | 17,230
Endocrine System 33 | 18,159
Respiratory system 33 | 16,393
Urinary Tract 33 | 16,678
Cardiovascular System 29 | 15,192
Nervous System 29 | 16,725

Target Family

Non-IDG 127 | 12,091
Enzyme 2 | 4,145
GPCR 1 | 408

KEGG Pathway

Autoimmune thyroid disease 130 | 130
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

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