Development Level

Tbio 24 | 10,625
Tchem 18 | 1,890
Tclin 4 | 602
Tdark 2 | 7,003

IMPC Term

abnormal behavior 2 | 226
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased circulating total pr... 2 | 41
decreased circulating triglyce... 2 | 83
decreased lean body mass 2 | 195
decreased startle reflex 2 | 48
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal lens morphology 1 | 73
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating bilirubi... 1 | 14
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating unsatura... 1 | 1
decreased erythrocyte cell num... 1 | 43
decreased food intake 1 | 6
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
female infertility 1 | 34
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased blood urea nitrogen ... 1 | 44
increased circulating insulin ... 1 | 2
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
increased startle reflex 1 | 38
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
thrombocytopenia 1 | 46

Disease

psoriasis 26 | 6,685
ovarian cancer 24 | 8,484
medulloblastoma, large-cell 21 | 6,234
osteosarcoma 21 | 7,933
glioblastoma 18 | 5,572
lung cancer 17 | 4,466
invasive ductal carcinoma 14 | 2,950
lung adenocarcinoma 14 | 2,713
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
Cancer 11 | 2,346
pediatric high grade glioma 11 | 2,712
primitive neuroectodermal tumor 11 | 3,031
atypical teratoid / rhabdoid tumor 10 | 4,369
interstitial cystitis 10 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
non-small cell lung cancer 10 | 2,798
group 3 medulloblastoma 9 | 2,254
oligodendroglioma 9 | 2,849
pancreatic cancer 9 | 2,300
subependymal giant cell astrocytoma 9 | 2,287
Intellectual disability 8 | 573
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
lung carcinoma 8 | 2,844
malignant mesothelioma 8 | 3,162
pituitary cancer 8 | 1,972
Asthma 7 | 349
atypical teratoid/rhabdoid tumor 7 | 1,095
breast carcinoma 7 | 1,614
nephrosclerosis 7 | 329
pilocytic astrocytoma 7 | 3,086
Kidney disease 6 | 396
Myocardial Infarction 6 | 126
Myopathy 6 | 128
Schizophrenia 6 | 501
Succinic semialdehyde dehydrogenase deficiency 6 | 16
astrocytic glioma 6 | 2,241
cutaneous lupus erythematosus 6 | 1,056
cystic fibrosis 6 | 1,665
diabetes mellitus 6 | 1,663
ependymoma 6 | 2,514
esophageal adenocarcinoma 6 | 737
posterior fossa group B ependymoma 6 | 1,530
primary pancreatic ductal adenocarcinoma 6 | 1,271
tuberculosis 6 | 1,557
ulcerative colitis 6 | 2,087
Breast cancer 5 | 3,094
Colonic Neoplasms 5 | 126
Duchenne muscular dystrophy 5 | 602
Liver Cirrhosis, Experimental 5 | 108
acute myeloid leukemia 5 | 780
acute quadriplegic myopathy 5 | 1,157
adult high grade glioma 5 | 2,148
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
dermatomyositis 5 | 933
gastric carcinoma 5 | 832
juvenile dermatomyositis 5 | 1,189
posterior fossa group A ependymoma 5 | 1,511
Alcohol dependence 4 | 107
Alzheimer's disease 4 | 644
Atopic dermatitis 4 | 944
Autistic Disorder 4 | 320
Cutis laxa 4 | 28
Dressler's syndrome 4 | 5
Gyrate atrophy 4 | 8
Leishmaniasis 4 | 49
Multiple myeloma 4 | 1,327
Necrotizing Enterocolitis 4 | 17
Obesity 4 | 616
Primary hyperoxaluria 4 | 15
Secondary progressive multiple sclerosis 4 | 9
fibroadenoma 4 | 557
medulloblastoma 4 | 1,524
sonic hedgehog group medulloblastoma 4 | 1,482
Atherosclerosis 3 | 275
Barrett's esophagus 3 | 183
Brain Ischemia 3 | 87
Cerebrovascular accident 3 | 44
Coronary artery disease 3 | 240
Dementia 3 | 129
Depressive disorder 3 | 48
Endometriosis 3 | 535
Esophageal Neoplasms 3 | 67
Hypertension 3 | 287
Hypertensive disease 3 | 193
Impotence 3 | 45
Necrosis 3 | 51
Parkinson Disease 3 | 102
Pick disease 3 | 1,893
Seizures 3 | 95
Stomach Neoplasms 3 | 282
Toxic encephalopathy 3 | 131
Vascular disease 3 | 281
adrenocortical carcinoma 3 | 1,427
chronic rhinosinusitis 3 | 512
non-inflammatory breast cancer 3 | 208
progressive supranuclear palsy 3 | 674
spina bifida 3 | 1,064

Tissue

Blood and immune system 48 | 17,995
Cardiovascular System 48 | 17,958
Digestive Tract 48 | 18,473
Endocrine System 48 | 18,512
Female tissues 48 | 18,647
Liver and Pancreas 48 | 18,136
Nervous System 48 | 18,561
Skin and soft tissues 48 | 18,115
Urinary Tract 48 | 18,444
Male tissues 47 | 17,969
Respiratory system 47 | 17,484

Target Family

Enzyme 44 | 4,146
Kinase 4 | 634

KEGG Pathway

Arginine and proline metabolis... 48 | 48
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyrroline-5-carboxylate reductase 3 PYCRL Tbio Enzyme 0.14 0.58 97
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.31313 210.4 193
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.11277 1238.0 122
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.32560 2206.3 649
Prolyl 4-hydroxylase subunit alpha-1 P4HA1 Tchem Enzyme -1.17728 13.6 143
Creatine kinase U-type, mitochondrial CKMT1A Tbio Kinase -1.92397 78.6 158
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.21924 1416.9 422
Prolyl 4-hydroxylase subunit alpha-2 P4HA2 Tchem Enzyme -0.86476 8.79 65
Creatine kinase B-type CKB Tbio Kinase -2.06806 117.8 364
Cytosol aminopeptidase LAP3 Tchem Enzyme -2.88198 662.1 140