Development Level

Tchem 27 | 1,388
Tbio 24 | 11,651
Tdark 7 | 6,593
Tclin 3 | 612

IMPC Phenotype

increased monocyte cell number 3 | 63
cataract 2 | 92
decreased lymphocyte cell numb... 2 | 83
preweaning lethality, incomple... 2 | 499
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
absent optic nerve 1 | 2
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hydrometra 1 | 53
increased body weight 1 | 25
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

psoriasis 29 | 6,694
Carcinoma 27 | 11,493
lung cancer 27 | 4,740
osteosarcoma 26 | 7,950
ovarian cancer 26 | 8,520
Cancer 22 | 2,499
non-small cell lung cancer 20 | 2,890
medulloblastoma, large-cell 19 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
lung carcinoma 18 | 2,843
pancreatic cancer 18 | 2,398
glioblastoma 17 | 5,792
interstitial cystitis 17 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
lung adenocarcinoma 16 | 2,716
atypical teratoid / rhabdoid tumor 15 | 5,112
Astrocytoma, Pilocytic 14 | 3,081
invasive ductal carcinoma 14 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
adult high grade glioma 13 | 3,801
diabetes mellitus 13 | 1,728
group 3 medulloblastoma 13 | 4,104
Schizophrenia 12 | 1,160
adrenocortical carcinoma 12 | 1,428
ependymoma 12 | 4,679
malignant mesothelioma 12 | 3,232
ulcerative colitis 12 | 1,819
primitive neuroectodermal tumor 11 | 3,035
Bipolar Disorder 10 | 666
Hypertension 10 | 396
cystic fibrosis 10 | 1,696
tuberculosis 10 | 2,010
Asthma 9 | 385
Atherosclerosis 9 | 291
Toxic encephalopathy 9 | 141
active Crohn's disease 9 | 922
colon cancer 9 | 1,478
esophageal adenocarcinoma 9 | 737
oligodendroglioma 9 | 2,850
Cerebrovascular disease 8 | 238
Coronary artery disease 8 | 268
Liver Cirrhosis, Experimental 8 | 769
Prostatic Neoplasms 8 | 495
astrocytoma 8 | 1,146
ductal carcinoma in situ 8 | 1,745
Arthritis 7 | 290
Breast cancer 7 | 3,578
Liver disease 7 | 237
Rheumatoid arthritis 7 | 1,191
breast carcinoma 7 | 1,638
subependymal giant cell astrocytoma 7 | 2,287
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
Depressive disorder 6 | 409
Endometriosis 6 | 540
Obesity 6 | 678
Osteoarthritis 6 | 184
head and neck cancer 6 | 271
pancreatic carcinoma 6 | 562
Breast Neoplasms 5 | 445
Chemical and Drug Induced Liver Injury 5 | 195
Drug-Related Side Effects and Adverse Reactions 5 | 62
Epilepsy 5 | 792
Kidney Failure, Chronic 5 | 46
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Reperfusion Injury 5 | 86
cutaneous lupus erythematosus 5 | 1,057
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
non primary Sjogren syndrome sicca 5 | 891
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
Actinic keratosis 4 | 21
Adverse reaction to drug 4 | 61
Alcoholic Intoxication, Chronic 4 | 289
Arthritis, Rheumatoid 4 | 174
Drug Hypersensitivity 4 | 34
Drug allergy 4 | 36
Duchenne muscular dystrophy 4 | 601
Dysmenorrhea 4 | 21
Fever 4 | 138
Hyperalgesia 4 | 83
Juvenile rheumatoid arthritis 4 | 111
Keshan disease 4 | 17
Lung Neoplasms 4 | 232
Menorrhagia 4 | 25
Mental Depression 4 | 333
Pain 4 | 103
Patent ductus arteriosus 4 | 90
Urticaria 4 | 67
Vascular disease 4 | 319
active ulcerative colitis 4 | 764
group 4 medulloblastoma 4 | 1,855
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
Kidney disease 3 | 430
acute quadriplegic myopathy 3 | 1,158
fibroadenoma 3 | 559
pediatric high grade glioma 3 | 1,064

Tissue

Digestive Tract 59 | 17,369
Male tissues 57 | 17,142
Skin and soft tissues 57 | 17,230
Female tissues 56 | 17,400
Blood and immune system 55 | 16,909
Endocrine System 55 | 18,159
Urinary Tract 55 | 16,678
Liver and Pancreas 54 | 16,750
Respiratory system 52 | 16,393
Nervous System 51 | 16,725
Cardiovascular System 44 | 15,192

Target Family

Enzyme 51 | 4,145
Non-IDG 10 | 12,091

KEGG Pathway

Arachidonic acid metabolism 61 | 61
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Group XIIB secretory phospholipase A2-like protein PLA2G12B Tdark Enzyme -0.46806 3.94 29
Group IID secretory phospholipase A2 PLA2G2D Tchem Enzyme -2.16892 139.3 119
Phospholipase B1, membrane-associated PLB1 Tdark Enzyme -1.65839 46.0 43
HRAS-like suppressor 3 PLA2G16 Tbio Non-IDG -1.96915 96.3 230
Glutathione peroxidase 7 GPX7 Tbio Enzyme -1.44661 30.0 155
Group 3 secretory phospholipase A2 PLA2G3 Tbio Enzyme -0.91137 8.37 128
Prostaglandin-H2 D-isomerase PTGDS Tbio Enzyme -2.58623 410.9 229
Group 10 secretory phospholipase A2 PLA2G10 Tchem Enzyme -2.41226 298.2 57
Glutathione hydrolase 5 proenzyme GGT5 Tbio Enzyme -1.89298 76.6 76
Cytochrome P450 2J2 CYP2J2 Tchem Non-IDG -2.12012 148.8 194