Development Level

Tbio 16 | 11,445
Tchem 16 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal bone structure 2 | 187
decreased mean corpuscular vol... 2 | 79
hyperactivity 2 | 148
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
absent testes 1 | 6
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased basophil cell number 1 | 7
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Cancer 28 | 2,499
ovarian cancer 20 | 8,520
Carcinoma 18 | 11,493
psoriasis 18 | 6,694
osteosarcoma 16 | 7,950
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
atypical teratoid / rhabdoid tumor 11 | 5,112
lung cancer 11 | 4,740
adult high grade glioma 10 | 3,801
ependymoma 10 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Alzheimer's disease 9 | 658
Vascular disease 9 | 319
group 3 medulloblastoma 9 | 4,104
tuberculosis 9 | 2,010
Astrocytoma, Pilocytic 8 | 3,081
Myocardial Reperfusion Injury 8 | 37
Toxic encephalopathy 8 | 141
invasive ductal carcinoma 8 | 2,951
Brain Ischemia 7 | 110
Breast cancer 7 | 3,578
Schizophrenia 7 | 1,160
adrenocortical carcinoma 7 | 1,428
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
Bipolar Disorder 6 | 666
Breast Neoplasms 6 | 445
Diabetes Mellitus, Type 2 6 | 142
Mammary Neoplasms 6 | 425
Myocardial Infarction 6 | 151
Stomach Neoplasms 6 | 300
hepatocellular carcinoma 6 | 547
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Cerebral Hemorrhage 5 | 42
Colonic Neoplasms 5 | 142
Diabetes Mellitus, Experimental 5 | 108
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Esophageal Neoplasms 5 | 69
Nerve Degeneration 5 | 121
Neurodegenerative disease 5 | 414
Parkinson's disease 5 | 392
Prostatic Neoplasms 5 | 495
Reperfusion Injury 5 | 86
group 4 medulloblastoma 5 | 1,855
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
Amyotrophic lateral sclerosis 4 | 451
Carcinoma, Hepatocellular 4 | 228
Depressive disorder 4 | 409
Edema 4 | 81
Heart disease 4 | 306
Kidney disease 4 | 430
Liver Neoplasms, Experimental 4 | 59
Liver carcinoma 4 | 240
Lung Neoplasms 4 | 232
Pick disease 4 | 1,894
Splenomegaly 4 | 190
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pancreatic carcinoma 4 | 562
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
Alzheimer Disease 3 | 83
Arthritis 3 | 290
Atopic dermatitis 3 | 952
Epilepsy 3 | 792
Eye disease 3 | 62
Fever 3 | 138
Hypersensitivity reaction type II disease 3 | 253
Inflammatory bowel disease 3 | 151
Kidney cancer 3 | 2,613
Leukemia 3 | 104
Liver Cirrhosis, Experimental 3 | 769
Lung disease 3 | 142
Melanoma 3 | 711
Mental Depression 3 | 333
Neuropathy 3 | 261
Retinal Detachment 3 | 51
Status Epilepticus 3 | 98
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 32 | 18,159
Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Digestive Tract 31 | 17,369
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678

Target Family

Non-IDG 24 | 12,091
Enzyme 7 | 4,145
Kinase 3 | 634

KEGG Pathway

Apoptosis - multiple species 34 | 34
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Beclin-2 BECN2 Tbio Non-IDG 0.00000 87
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833
Bcl-2-related ovarian killer protein BOK Tbio Non-IDG -1.64193 42.6 207
Septin-4 SEPT4 Tbio Non-IDG -2.38258 232.7 201
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800
Baculoviral IAP repeat-containing protein 6 BIRC6 Tbio Non-IDG -1.79775 61.4 168