Development Level

Tbio 133 | 11,651
Tchem 13 | 1,388
Tdark 9 | 6,593
Tclin 1 | 612

IMPC Phenotype

embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
short tibia 2 | 97
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74

Disease

Cancer 100 | 2,499
diabetes mellitus 83 | 1,728
psoriasis 81 | 6,694
Ankylosing spondylitis 75 | 140
Behcet's disease 72 | 89
Hypersensitivity reaction type II disease 66 | 253
Carcinoma 65 | 11,493
Juvenile rheumatoid arthritis 64 | 111
Rheumatoid arthritis 64 | 1,191
Arthritis 63 | 290
Uveitis 60 | 103
Acquired immunodeficiency syndrome 59 | 197
Herpes zoster 57 | 68
Human immunodeficiency virus infectious disease 53 | 138
Psoriatic arthritis 53 | 86
Stevens-Johnson syndrome 51 | 92
dermatomyositis 49 | 966
ovarian cancer 41 | 8,520
tuberculosis 39 | 2,010
Dermatitis 38 | 157
Multiple Sclerosis 36 | 540
Synovitis 36 | 78
Takayasu's arteritis 36 | 53
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
osteosarcoma 34 | 7,950
glioblastoma 33 | 5,792
lung cancer 31 | 4,740
Hepatitis B 29 | 108
Liver disease 28 | 237
Kidney disease 26 | 430
Leprosy 26 | 73
Anemia 25 | 365
Hemochromatosis 24 | 54
lung carcinoma 24 | 2,843
subependymal giant cell astrocytoma 24 | 2,287
Primary immunodeficiency disease 23 | 54
juvenile dermatomyositis 23 | 1,187
Astrocytoma, Pilocytic 21 | 3,081
Birdshot chorioretinopathy 21 | 23
Skin disease 21 | 66
medulloblastoma, large-cell 20 | 6,241
cutaneous lupus erythematosus 19 | 1,057
interstitial cystitis 18 | 2,312
sarcoidosis 18 | 370
Narcolepsy 17 | 72
Schizophrenia 17 | 1,160
invasive ductal carcinoma 17 | 2,951
Berylliosis 16 | 28
Human immunodeficiency virus type 1, susceptibility to 16 | 26
active Crohn's disease 16 | 922
adult high grade glioma 16 | 3,801
Pre-Eclampsia 15 | 68
breast carcinoma 15 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
primary Sjogren syndrome 15 | 735
Duchenne muscular dystrophy 14 | 601
Multiple Sclerosis, Susceptibility to 14 | 15
Multiple myeloma 14 | 1,332
Narcolepsy-cataplexy 14 | 21
Psoriasis susceptibility 1 14 | 14
Systemic lupus erythematosus 14 | 194
astrocytoma 14 | 1,146
non-small cell lung cancer 14 | 2,890
Diffuse cutaneous systemic sclerosis 13 | 17
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
ependymoma 13 | 4,679
follicular lymphoma 13 | 20
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
limited scleroderma 13 | 19
active ulcerative colitis 12 | 764
atypical teratoid / rhabdoid tumor 12 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
pancreatic cancer 12 | 2,398
Bipolar Disorder 11 | 666
Breast cancer 11 | 3,578
esophageal adenocarcinoma 11 | 737
malignant mesothelioma 11 | 3,232
cystic fibrosis 10 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung adenocarcinoma 10 | 2,716
ulcerative colitis 10 | 1,819
Autosomal recessive predisposition 9 | 1,442
HIV Infections 9 | 102
Waldenstrons macroglobulinemia 9 | 765
group 3 medulloblastoma 9 | 4,104
Hypersensitivity 8 | 63
Proteinuria 8 | 144
Vasculitis 8 | 80
group 4 medulloblastoma 8 | 1,855
Asthma 7 | 385
Becker muscular dystrophy 7 | 191
acute quadriplegic myopathy 7 | 1,158
adrenocortical carcinoma 7 | 1,428
oligodendroglioma 7 | 2,850

Tissue

Blood and immune system 61 | 16,909
Respiratory system 60 | 16,393
Digestive Tract 59 | 17,369
Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Liver and Pancreas 59 | 16,750
Skin and soft tissues 59 | 17,230
Male tissues 58 | 17,142
Urinary Tract 58 | 16,678
Nervous System 55 | 16,725
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 145 | 12,091
Enzyme 6 | 4,145
Transcription Factor 5 | 1,400

KEGG Pathway

Antigen processing and present... 156 | 156
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0