Development Level

Tbio 129 | 10,625
Tchem 16 | 1,890
Tdark 10 | 7,003
Tclin 1 | 602

IMPC Term

decreased body length 2 | 108
decreased total body fat amoun... 2 | 186
abnormal head morphology 1 | 10
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased circulating insulin ... 1 | 75
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
male infertility 1 | 62
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
shortened head 1 | 2

Disease

Cancer 98 | 2,346
diabetes mellitus 82 | 1,663
psoriasis 79 | 6,685
Ankylosing spondylitis 75 | 138
Hypersensitivity reaction type II disease 66 | 235
Juvenile rheumatoid arthritis 63 | 104
Arthritis 61 | 248
Acquired immunodeficiency syndrome 60 | 164
Uveitis 59 | 103
Behcet's disease 58 | 74
Psoriatic arthritis 53 | 83
Rheumatoid Arthritis 53 | 1,160
ovarian cancer 41 | 8,484
Stevens-Johnson syndrome 38 | 78
Multiple Sclerosis 37 | 498
Takayasu's arteritis 36 | 52
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
osteosarcoma 34 | 7,933
glioblastoma 33 | 5,572
lung cancer 31 | 4,466
Liver disease 27 | 219
Kidney disease 26 | 396
Leprosy 26 | 77
Hepatitis B 25 | 103
Anemia 24 | 252
Hemochromatosis 24 | 55
lung carcinoma 24 | 2,844
subependymal giant cell astrocytoma 24 | 2,287
Primary immunodeficiency disease 23 | 52
juvenile dermatomyositis 23 | 1,189
Skin disease 21 | 65
pilocytic astrocytoma 21 | 3,086
medulloblastoma, large-cell 20 | 6,234
astrocytoma 19 | 1,493
cutaneous lupus erythematosus 19 | 1,056
dermatomyositis 18 | 933
interstitial cystitis 18 | 2,299
Human immunodeficiency virus infectious disease 17 | 92
invasive ductal carcinoma 17 | 2,950
primary Sjogren syndrome 17 | 789
active Crohn's disease 16 | 918
breast carcinoma 15 | 1,614
pre-eclampsia 15 | 67
Duchenne muscular dystrophy 14 | 602
Multiple myeloma 14 | 1,327
non-small cell lung cancer 14 | 2,798
tuberculosis 14 | 1,557
adult high grade glioma 13 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
posterior fossa group A ependymoma 13 | 1,511
ulcerative colitis 13 | 2,087
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
pancreatic cancer 12 | 2,300
atypical teratoid / rhabdoid tumor 11 | 4,369
esophageal adenocarcinoma 11 | 737
cystic fibrosis 10 | 1,665
group 4 medulloblastoma 10 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
lung adenocarcinoma 10 | 2,713
malignant mesothelioma 10 | 3,162
Breast cancer 9 | 3,094
HIV Infections 9 | 100
Waldenstrons macroglobulinemia 9 | 765
active ulcerative colitis 9 | 477
pediatric high grade glioma 9 | 2,712
Asthma 8 | 349
Hypersensitivity 8 | 63
sarcoidosis 8 | 358
Down syndrome 7 | 548
Narcolepsy 7 | 58
Type 1 diabetes mellitus 7 | 101
acute quadriplegic myopathy 7 | 1,157
adrenocortical carcinoma 7 | 1,427
colon cancer 7 | 1,475
limb girdle muscular dystrophy 2I 7 | 56
oligodendroglioma 7 | 2,849
Becker muscular dystrophy 6 | 187
Diabetes Mellitus, Insulin-Dependent 6 | 76
Drug-Induced Liver Injury 6 | 118
IGA Glomerulonephritis 6 | 454
Proteinuria 6 | 63
Vascular disease 6 | 281
ependymoma 6 | 2,514
pancreatic carcinoma 6 | 567
pituitary cancer 6 | 1,972
tuberculosis and treatment for 3 months 6 | 327
Alzheimer's disease 5 | 644
Chagas disease 5 | 34
Heart disease 5 | 279
Lung disease 5 | 132
Mammary Neoplasms 5 | 410
Myocardial Ischemia 5 | 169
Parkinson's disease 5 | 364
Prostatic Neoplasms 5 | 471
Vasculitis 5 | 64
acute myeloid leukemia 5 | 780
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
primary pancreatic ductal adenocarcinoma 5 | 1,271

Tissue

Blood and immune system 83 | 17,995
Digestive Tract 77 | 18,473
Female tissues 77 | 18,647
Liver and Pancreas 77 | 18,136
Nervous System 77 | 18,561
Respiratory system 76 | 17,484
Urinary Tract 76 | 18,444
Endocrine System 75 | 18,512
Cardiovascular System 74 | 17,958
Male tissues 74 | 17,969
Skin and soft tissues 64 | 18,115

Target Family

Non-IDG 145 | 11,971
Enzyme 6 | 4,146
Transcription Factor 5 | 1,400

KEGG Pathway

Antigen processing and present... 156 | 156
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

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