Development Level

Tbio 23 | 11,445
Tchem 18 | 1,598
Tclin 9 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased circulating triglyce... 2 | 79
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cataract 1 | 92
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 50
enlarged epididymis 1 | 31
hyperactivity 1 | 148
increased basophil cell number 1 | 7
increased bone mineral content 1 | 108
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
male infertility 1 | 123
small testis 1 | 58

Disease

glioblastoma 31 | 5,792
Carcinoma 29 | 11,493
medulloblastoma, large-cell 28 | 6,241
psoriasis 27 | 6,694
Cancer 25 | 2,499
ovarian cancer 25 | 8,520
atypical teratoid / rhabdoid tumor 24 | 5,112
Schizophrenia 22 | 1,160
osteosarcoma 22 | 7,950
Toxic encephalopathy 21 | 141
adult high grade glioma 21 | 3,801
ependymoma 21 | 4,679
lung cancer 20 | 4,740
Alzheimer's disease 19 | 658
Astrocytoma, Pilocytic 19 | 3,081
oligodendroglioma 17 | 2,850
Depressive disorder 16 | 409
Parkinson's disease 14 | 392
group 3 medulloblastoma 14 | 4,104
Bipolar Disorder 13 | 666
Brain Ischemia 13 | 110
Vascular disease 13 | 319
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
malignant mesothelioma 13 | 3,232
primitive neuroectodermal tumor 13 | 3,035
subependymal giant cell astrocytoma 13 | 2,287
Amyotrophic lateral sclerosis 12 | 451
Mental Depression 12 | 333
Pick disease 12 | 1,894
astrocytic glioma 12 | 2,597
diabetes mellitus 12 | 1,728
group 4 medulloblastoma 12 | 1,855
lung carcinoma 12 | 2,843
Diabetes Mellitus, Experimental 11 | 108
Nerve Degeneration 10 | 121
Rheumatoid arthritis 10 | 1,191
adrenocortical carcinoma 10 | 1,428
tuberculosis 10 | 2,010
Diabetes Mellitus, Non-Insulin-Dependent 9 | 145
Diabetes Mellitus, Type 2 9 | 142
Epilepsy 9 | 792
Kidney cancer 9 | 2,613
Kidney disease 9 | 430
Hypertension 8 | 396
Major Depressive Disorder 8 | 301
Multiple myeloma 8 | 1,332
Myocardial Infarction 8 | 151
Neurodegenerative disease 8 | 414
Obesity 8 | 678
colon cancer 8 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung adenocarcinoma 8 | 2,716
Autistic Disorder 7 | 364
Breast cancer 7 | 3,578
General anesthesia 7 | 53
Local anesthesia 7 | 40
Melanoma 7 | 711
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
AMYOTROPHIC LATERAL SCLEROSIS 1 6 | 49
Alcoholic Intoxication, Chronic 6 | 289
Brain disease 6 | 96
Breast Neoplasms 6 | 445
Cerebrovascular disease 6 | 238
Edema 6 | 81
Hypersensitivity reaction type II disease 6 | 253
Hypertensive disease 6 | 292
Mammary Neoplasms 6 | 425
Myocardial Reperfusion Injury 6 | 37
Prostatic Neoplasms 6 | 495
Reperfusion Injury 6 | 86
Status Epilepticus 6 | 98
Unipolar Depression 6 | 250
aldosterone-producing adenoma 6 | 665
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Carcinoma, Hepatocellular 5 | 228
Cardiomyopathies 5 | 110
Colonic Neoplasms 5 | 142
Heart disease 5 | 306
Heart failure 5 | 162
Huntington's disease 5 | 76
Hypersensitivity 5 | 63
Liver carcinoma 5 | 240
Lung Neoplasms 5 | 232
Lung disease 5 | 142
Multiple Sclerosis 5 | 540
Neuropathy 5 | 261
Parkinson Disease 5 | 64
Parkinsonism 5 | 18
Seizures 5 | 596
Skin cancer 5 | 469
Stomach Neoplasms 5 | 300
Waldenstrons macroglobulinemia 5 | 765
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
medulloblastoma 5 | 720
non-small cell lung cancer 5 | 2,890
ulcerative colitis 5 | 1,819

Tissue

Endocrine System 50 | 18,159
Digestive Tract 49 | 17,369
Nervous System 49 | 16,725
Skin and soft tissues 49 | 17,230
Blood and immune system 48 | 16,909
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Respiratory system 47 | 16,393
Urinary Tract 47 | 16,678
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 15 | 4,145
Ion Channel 7 | 344
Kinase 7 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

KEGG Pathway

Amyotrophic lateral sclerosis ... 51 | 51
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Derlin-1 DERL1 Tbio Non-IDG -1.88253 69.7 178
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Calcineurin subunit B type 1 PPP3R1 Tbio Non-IDG -2.60752 391.4 125
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Mitochondrial import receptor subunit TOM40B TOMM40L Tdark Non-IDG 0.04 0.80 55
Copper chaperone for superoxide dismutase CCS Tbio Enzyme -1.76183 50.7 209
Dual specificity mitogen-activated protein kinase kinase 3 MAP2K3 Tchem Kinase -2.35301 190.9 1060
Glutathione peroxidase 1 GPX1 Tbio Enzyme -2.94289 886.7 350
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565