Development Level

Tbio 67 | 11,445
Tchem 22 | 1,598
Tclin 9 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

increased heart weight 6 | 62
increased startle reflex 6 | 112
abnormal bone structure 4 | 187
decreased total body fat amoun... 4 | 207
preweaning lethality, complete... 4 | 979
decreased circulating amylase ... 3 | 28
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular hem... 3 | 50
increased neutrophil cell numb... 3 | 46
abnormal behavior 2 | 298
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 39
increased or absent threshold ... 2 | 101
persistence of hyaloid vascula... 2 | 33
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
shortened RR interval 2 | 17
small superior vagus ganglion 2 | 74
vertebral fusion 2 | 23
abnormal cecum morphology 1 | 7
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
male infertility 1 | 123

Disease

Carcinoma 74 | 11,493
ovarian cancer 58 | 8,520
psoriasis 58 | 6,694
lung cancer 51 | 4,740
glioblastoma 47 | 5,792
Cancer 46 | 2,499
medulloblastoma, large-cell 40 | 6,241
lung carcinoma 38 | 2,843
pancreatic cancer 37 | 2,398
Breast cancer 36 | 3,578
Kidney cancer 36 | 2,613
malignant mesothelioma 36 | 3,232
atypical teratoid / rhabdoid tumor 35 | 5,112
ependymoma 35 | 4,679
Astrocytoma, Pilocytic 34 | 3,081
ulcerative colitis 34 | 1,819
interstitial cystitis 32 | 2,312
osteosarcoma 32 | 7,950
cystic fibrosis 30 | 1,696
adult high grade glioma 29 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
tuberculosis 28 | 2,010
Schizophrenia 27 | 1,160
invasive ductal carcinoma 27 | 2,951
lung adenocarcinoma 27 | 2,716
non-small cell lung cancer 27 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
diabetes mellitus 25 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
subependymal giant cell astrocytoma 24 | 2,287
Kidney disease 23 | 430
Autosomal recessive predisposition 22 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
primitive neuroectodermal tumor 22 | 3,035
Liver Cirrhosis, Experimental 21 | 769
colon cancer 21 | 1,478
group 3 medulloblastoma 21 | 4,104
nasopharyngeal carcinoma 21 | 1,058
oligodendroglioma 21 | 2,850
cutaneous lupus erythematosus 20 | 1,057
juvenile dermatomyositis 20 | 1,187
Asthma 19 | 385
pituitary cancer 19 | 1,972
Melanoma 18 | 711
Arthritis 17 | 290
Hypertensive disease 17 | 292
Inflammatory bowel disease 17 | 151
Rheumatoid arthritis 17 | 1,191
active ulcerative colitis 17 | 764
breast carcinoma 17 | 1,638
gastric carcinoma 17 | 807
Duchenne muscular dystrophy 16 | 601
active Crohn's disease 16 | 922
astrocytoma 16 | 1,146
ductal carcinoma in situ 16 | 1,745
Liver cancer 15 | 604
Multiple Sclerosis 15 | 540
dermatomyositis 15 | 966
esophageal adenocarcinoma 15 | 737
Pneumonia 14 | 174
Skin cancer 14 | 469
periodontitis 14 | 293
Atopic dermatitis 13 | 952
Hypersensitivity reaction type II disease 13 | 253
Hypertension 13 | 396
Obesity 13 | 678
Reperfusion Injury 13 | 86
Seizures 13 | 596
adrenocortical carcinoma 13 | 1,428
astrocytic glioma 13 | 2,597
Anemia 12 | 365
Dermatitis 12 | 157
Osteoporosis 12 | 363
Prostatic Neoplasms 12 | 495
Pulmonary Fibrosis 12 | 106
group 4 medulloblastoma 12 | 1,855
Abortion, Spontaneous 11 | 109
Atherosclerosis 11 | 291
Bipolar Disorder 11 | 666
Depressive disorder 11 | 409
Endometriosis 11 | 540
Epilepsy 11 | 792
Fever 11 | 138
Heart disease 11 | 306
Inflammation 11 | 120
Liver disease 11 | 237
Lung disease 11 | 142
Meningitis 11 | 67
Myopia 11 | 176
Pick disease 11 | 1,894
Spontaneous abortion 11 | 113
Vasculitis 11 | 80
primary pancreatic ductal adenocarcinoma 11 | 1,109
Coronary artery disease 10 | 268
Crohn's disease 10 | 321
Influenza 10 | 142
Leishmaniasis 10 | 47
Liver carcinoma 10 | 240
Lung Neoplasms 10 | 232
Malaria 10 | 160

Tissue

Endocrine System 93 | 18,159
Liver and Pancreas 92 | 16,750
Blood and immune system 91 | 16,909
Digestive Tract 91 | 17,369
Female tissues 91 | 17,400
Male tissues 91 | 17,142
Skin and soft tissues 91 | 17,230
Urinary Tract 91 | 16,678
Respiratory system 89 | 16,393
Nervous System 87 | 16,725
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 67 | 12,091
Enzyme 18 | 4,145
Kinase 11 | 634
Transcription Factor 2 | 1,400

KEGG Pathway

Amoebiasis 98 | 98
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Arginase-2, mitochondrial ARG2 Tchem Enzyme -2.46702 275.2 245
Mucin-2 MUC2 Tbio Non-IDG -2.89417 752.2 0
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Leukocyte elastase inhibitor SERPINB1 Tbio Enzyme -2.55345 336.3 370
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248