Development Level

Tclin 15 | 613
Tchem 12 | 1,598
Tbio 8 | 11,445
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased circulating creatini... 2 | 39
preweaning lethality, incomple... 2 | 499
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
absent startle reflex 1 | 24
decreased body weight 1 | 161
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101

Disease

Carcinoma 25 | 11,493
psoriasis 23 | 6,694
ovarian cancer 22 | 8,520
medulloblastoma, large-cell 21 | 6,241
atypical teratoid / rhabdoid tumor 19 | 5,112
glioblastoma 19 | 5,792
Breast cancer 16 | 3,578
Cancer 16 | 2,499
Hypertension 16 | 396
lung cancer 16 | 4,740
adult high grade glioma 15 | 3,801
osteosarcoma 15 | 7,950
Hypertensive disease 13 | 292
interstitial cystitis 13 | 2,312
ependymoma 12 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
invasive ductal carcinoma 12 | 2,951
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 12 | 3,035
cystic fibrosis 11 | 1,696
diabetes mellitus 11 | 1,728
Autosomal recessive predisposition 10 | 1,442
Failure to gain weight 10 | 365
Kidney cancer 10 | 2,613
Kidney disease 10 | 430
Pediatric failure to thrive 10 | 365
ductal carcinoma in situ 10 | 1,745
group 3 medulloblastoma 10 | 4,104
malignant mesothelioma 10 | 3,232
Astrocytoma, Pilocytic 9 | 3,081
Atrial Fibrillation 9 | 124
Chronic heart failure 9 | 46
Congestive heart failure 9 | 113
Diarrhea 9 | 253
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Cognitive delay 8 | 608
Epilepsy 8 | 792
Global developmental delay 8 | 608
Hyperaldosteronism 8 | 35
Mental and motor retardation 8 | 608
Poisoning by digitalis glycoside 8 | 8
juvenile dermatomyositis 8 | 1,187
lung carcinoma 8 | 2,843
non-small cell lung cancer 8 | 2,890
oligodendroglioma 8 | 2,850
Adenoma 7 | 167
Bipolar Disorder 7 | 666
Depressive disorder 7 | 409
Hyperglycemia 7 | 137
Intellectual disability 7 | 1,016
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
Seizures 7 | 596
astrocytic glioma 7 | 2,597
breast carcinoma 7 | 1,638
subependymal giant cell astrocytoma 7 | 2,287
Dehydration 6 | 40
Dull intelligence 6 | 645
Endometriosis 6 | 540
Hypokalemia 6 | 52
Low Birth Weights 6 | 69
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Metabolic acidosis 6 | 90
Obesity 6 | 678
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
Short stature 6 | 531
Small for gestational age (disorder) 6 | 69
adrenocortical carcinoma 6 | 1,428
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
pancreatic cancer 6 | 2,398
Alzheimer's disease 5 | 658
Arthritis 5 | 290
Constipation 5 | 181
Dyschezia 5 | 135
Feeding difficulties in infancy 5 | 175
Frontal bossing 5 | 157
Heart disease 5 | 306
Hyperalgesia 5 | 83
Infantile onset 5 | 238
Intrauterine retardation 5 | 176
Muscle Weakness 5 | 170
Neoplasm Metastasis 5 | 168
Parkinson's disease 5 | 392
Polycystic ovary syndrome 5 | 360
Recurrent respiratory infections 5 | 141
Stomach Neoplasms 5 | 300
Vomiting 5 | 116
nasopharyngeal carcinoma 5 | 1,058
nephrosclerosis 5 | 333
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074
ulcerative colitis 5 | 1,819

Tissue

Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Nervous System 37 | 16,725
Skin and soft tissues 37 | 17,230
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Blood and immune system 35 | 16,909
Respiratory system 35 | 16,393
Urinary Tract 35 | 16,678
Cardiovascular System 33 | 15,192

Target Family

Kinase 12 | 634
Transporter 9 | 473
Enzyme 6 | 4,145
Ion Channel 5 | 344
Non-IDG 4 | 12,091
Nuclear Receptor 1 | 48

KEGG Pathway

Aldosterone-regulated sodium r... 37 | 37
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.24223 170.0 132
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.12480 136.2 116
ATP-sensitive inward rectifier potassium channel 1 KCNJ1 Tchem Ion Channel -2.50371 327.8 188
FXYD domain-containing ion transport regulator 4 FXYD4 Tdark Ion Channel -0.81692 5.29 14
Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 Tclin Transporter -1.68777 43.2 399
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435