Development Level

Tbio 69 | 10,625
Tclin 33 | 602
Tdark 26 | 7,003
Tchem 17 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal bone structure 6 | 131
abnormal bone mineralization 5 | 55
increased heart weight 4 | 37
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
decreased bone mineral content 3 | 157
decreased lean body mass 3 | 195
increased circulating alkaline... 3 | 119
decreased body length 2 | 108
decreased bone mineral density 2 | 126
hypoactivity 2 | 89
increased blood urea nitrogen ... 2 | 44
preweaning lethality, complete... 2 | 633
abnormal cervical vertebrae mo... 1 | 4
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
cataract 1 | 26
convulsive seizures 1 | 11
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
hyperactivity 1 | 108
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased circulating HDL chol... 1 | 63
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
rib fusion 1 | 2
short tibia 1 | 82
small kidney 1 | 10
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

ovarian cancer 60 | 8,484
glioblastoma 58 | 5,572
psoriasis 57 | 6,685
medulloblastoma, large-cell 54 | 6,234
osteosarcoma 52 | 7,933
Cancer 44 | 2,346
atypical teratoid / rhabdoid tumor 42 | 4,369
lung cancer 41 | 4,466
pilocytic astrocytoma 40 | 3,086
pediatric high grade glioma 38 | 2,712
Breast cancer 37 | 3,094
primitive neuroectodermal tumor 35 | 3,031
invasive ductal carcinoma 32 | 2,950
Multiple myeloma 31 | 1,327
lung adenocarcinoma 30 | 2,713
oligodendroglioma 29 | 2,849
subependymal giant cell astrocytoma 27 | 2,287
breast carcinoma 26 | 1,614
ependymoma 26 | 2,514
Parkinson's disease 24 | 364
Schizophrenia 24 | 501
pancreatic cancer 24 | 2,300
Pick disease 23 | 1,893
astrocytoma 23 | 1,493
malignant mesothelioma 23 | 3,162
astrocytic glioma 22 | 2,241
ductal carcinoma in situ 22 | 1,745
lung carcinoma 22 | 2,844
non-small cell lung cancer 22 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
pituitary cancer 21 | 1,972
group 3 medulloblastoma 20 | 2,254
medulloblastoma 20 | 1,524
ulcerative colitis 19 | 2,087
group 4 medulloblastoma 18 | 1,875
Carcinoma 17 | 2,147
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
Cocaine-Related Disorders 16 | 88
Obesity 16 | 616
Toxic encephalopathy 16 | 131
atypical teratoid/rhabdoid tumor 16 | 1,095
posterior fossa group A ependymoma 16 | 1,511
colon cancer 15 | 1,475
cystic fibrosis 15 | 1,665
Bipolar Disorder 14 | 266
Intellectual disability 14 | 573
diabetes mellitus 14 | 1,663
interstitial cystitis 14 | 2,299
Alzheimer's disease 13 | 644
Epilepsy 13 | 346
Rheumatoid Arthritis 13 | 1,160
non-small cell lung carcinoma 13 | 413
Alcohol dependence 12 | 107
Huntington's disease 12 | 72
Substance Withdrawal Syndrome 12 | 52
cutaneous lupus erythematosus 12 | 1,056
Major Depressive Disorder 11 | 106
Peripheral T-cell lymphoma 11 | 24
Primary cutaneous T-cell lymphoma 11 | 24
hepatocellular carcinoma 11 | 532
sonic hedgehog group medulloblastoma 11 | 1,482
Parkinsonism 10 | 19
Postencephalitic parkinsonism 10 | 12
Substance abuse 10 | 55
Waldenstrons macroglobulinemia 10 | 765
adult high grade glioma 10 | 2,148
juvenile dermatomyositis 10 | 1,189
pancreatic carcinoma 10 | 567
tuberculosis 10 | 1,557
Adenoma 9 | 165
Autistic Disorder 9 | 320
Noonan Syndrome 9 | 33
Vascular disease 9 | 281
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
posterior fossa group B ependymoma 9 | 1,530
Endometriosis 8 | 535
General anesthesia 8 | 53
Hypotension 8 | 53
Local anesthesia 8 | 40
Mammary Neoplasms 8 | 410
Nerve Degeneration 8 | 73
Parkinson Disease 8 | 102
Seizures 8 | 95
Arteriosclerotic Parkinsonism 7 | 8
Attention deficit hyperactivity disorder 7 | 156
Cerebrovascular disease 7 | 231
Depressive disorder 7 | 48
Extrapyramidal disease 7 | 8
Hyperactive behavior 7 | 31
Kidney cancer 7 | 118
active Crohn's disease 7 | 918
acute myeloid leukemia 7 | 780
aldosterone-producing adenoma 7 | 664
dermatomyositis 7 | 933
esophageal adenocarcinoma 7 | 737
gastric cancer 7 | 430
nasopharyngeal carcinoma 7 | 1,056
non primary Sjogren syndrome sicca 7 | 840
primary pancreatic ductal adenocarcinoma 7 | 1,271

Tissue

Female tissues 143 | 18,647
Male tissues 142 | 17,969
Endocrine System 141 | 18,512
Nervous System 141 | 18,561
Urinary Tract 141 | 18,444
Blood and immune system 140 | 17,995
Cardiovascular System 140 | 17,958
Digestive Tract 140 | 18,473
Liver and Pancreas 140 | 18,136
Respiratory system 137 | 17,484
Skin and soft tissues 129 | 18,115

Target Family

Non-IDG 83 | 11,971
Enzyme 13 | 4,146
Epigenetic 12 | 242
Kinase 11 | 634
Transcription Factor 11 | 1,400
Ion Channel 7 | 341
GPCR 4 | 406
Transporter 4 | 473

KEGG Pathway

Alcoholism 145 | 145
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Cyclic AMP-responsive element-binding protein 3 CREB3 Tbio Transcription Factor -1.61736 42.0 159
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -2.99303 933.5 424
Histone H4 HIST2H4A Tbio Non-IDG -2.57230 138.5 770
Histone H2B type 1-C/E/F/G/I HIST1H2BC Tbio Non-IDG -1.35785 22.1 103
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 GNB2 Tbio Non-IDG -0.43889 2.98 102
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 Tbio Non-IDG -1.15715 18.1 144