Development Level

Tbio 75 | 11,445
Tclin 35 | 613
Tdark 21 | 6,588
Tchem 16 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal bone structure 6 | 187
increased startle reflex 6 | 112
preweaning lethality, incomple... 6 | 499
increased heart weight 4 | 62
abnormal behavior 2 | 298
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body length 2 | 101
decreased bone mineral content 2 | 151
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged spleen 1 | 41
hyperactivity 1 | 148
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
male infertility 1 | 123
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
shortened QRS complex duration 1 | 1
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 79 | 11,493
ovarian cancer 64 | 8,520
glioblastoma 63 | 5,792
psoriasis 58 | 6,694
medulloblastoma, large-cell 55 | 6,241
atypical teratoid / rhabdoid tumor 53 | 5,112
osteosarcoma 53 | 7,950
lung cancer 49 | 4,740
Cancer 47 | 2,499
Breast cancer 44 | 3,578
Schizophrenia 44 | 1,160
ependymoma 43 | 4,679
group 3 medulloblastoma 41 | 4,104
Astrocytoma, Pilocytic 38 | 3,081
primitive neuroectodermal tumor 36 | 3,035
Multiple myeloma 32 | 1,332
adult high grade glioma 32 | 3,801
invasive ductal carcinoma 32 | 2,951
lung adenocarcinoma 30 | 2,716
oligodendroglioma 30 | 2,850
Depressive disorder 29 | 409
Mental Depression 28 | 333
subependymal giant cell astrocytoma 28 | 2,287
astrocytic glioma 27 | 2,597
breast carcinoma 27 | 1,638
malignant mesothelioma 25 | 3,232
pancreatic cancer 25 | 2,398
Parkinson's disease 24 | 392
Pick disease 24 | 1,894
non-small cell lung cancer 24 | 2,890
Bipolar Disorder 23 | 666
Alcoholic Intoxication, Chronic 22 | 289
Epilepsy 22 | 792
ductal carcinoma in situ 22 | 1,745
group 4 medulloblastoma 22 | 1,855
lung carcinoma 22 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
pituitary cancer 21 | 1,972
Intellectual disability 19 | 1,016
diabetes mellitus 19 | 1,728
Mood Disorders 18 | 184
Obesity 18 | 678
Toxic encephalopathy 18 | 141
astrocytoma 18 | 1,146
Kidney cancer 17 | 2,613
Major Depressive Disorder 17 | 301
Seizures 17 | 596
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
ulcerative colitis 17 | 1,819
Cocaine-Related Disorders 16 | 92
Unipolar Depression 16 | 250
pediatric high grade glioma 16 | 1,064
Alzheimer's disease 15 | 658
Substance Withdrawal Syndrome 15 | 55
colon cancer 15 | 1,478
cystic fibrosis 15 | 1,696
Short stature 14 | 531
interstitial cystitis 14 | 2,312
Rheumatoid arthritis 13 | 1,191
Alcohol dependence 12 | 107
Blepharoptosis 12 | 231
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Huntington's disease 12 | 76
Mental and motor retardation 12 | 608
cutaneous lupus erythematosus 12 | 1,057
Attention deficit hyperactivity disorder 11 | 278
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Peripheral T-cell lymphoma 11 | 25
Poor school performance 11 | 645
Primary cutaneous T-cell lymphoma 11 | 29
hepatocellular carcinoma 11 | 547
Cerebrovascular disease 10 | 238
Hypertension 10 | 396
Melanoma 10 | 711
Muscle hypotonia 10 | 571
Parkinsonism 10 | 18
Postencephalitic parkinsonism 10 | 12
Substance abuse 10 | 59
Waldenstrons macroglobulinemia 10 | 765
juvenile dermatomyositis 10 | 1,187
non-small cell lung carcinoma 10 | 317
pancreatic carcinoma 10 | 562
tuberculosis 10 | 2,010
Adenoma 9 | 167
Alcoholism 9 | 45
Cryptorchidism 9 | 296
Downward slant of palpebral fissure 9 | 158
Dysarthria 9 | 192
Hypoplastic mandible condyle 9 | 275
Hypotension 9 | 82
Mandibular hypoplasia 9 | 275
Micrognathism 9 | 275
Noonan syndrome 9 | 34
Vascular disease 9 | 319
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962

Tissue

Endocrine System 144 | 18,159
Digestive Tract 141 | 17,369
Female tissues 141 | 17,400
Skin and soft tissues 140 | 17,230
Blood and immune system 139 | 16,909
Nervous System 137 | 16,725
Liver and Pancreas 136 | 16,750
Male tissues 135 | 17,142
Respiratory system 132 | 16,393
Urinary Tract 132 | 16,678
Cardiovascular System 125 | 15,192

Target Family

Non-IDG 85 | 12,091
Enzyme 13 | 4,145
Epigenetic 12 | 242
Kinase 11 | 634
Transcription Factor 11 | 1,400
Ion Channel 7 | 344
GPCR 4 | 408
Transporter 4 | 473

KEGG Pathway

Alcoholism 147 | 147
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A.J H2AFJ Tdark Non-IDG -0.00172 0.83 99
Histone H2A type 1-A HIST1H2AA Tbio Non-IDG -0.84480 8.19 69
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Histone H2B type 1-N HIST1H2BN Tbio Non-IDG -1.51422 30.2 60
Histone H2B type 1-L HIST1H2BL Tdark Non-IDG 0.35 0.40 48
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Histone H2B type 1-M HIST1H2BM Tdark Non-IDG 0.17 0.33 21
Amine oxidase [flavin-containing] B MAOB Tclin Enzyme -3.40865 2530.3 252
Histone H2A type 1-J HIST1H2AJ Tdark Non-IDG -0.13212 1.19 16
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448